Antioxidant Capacity, Anti-Wrinkle and Whitening Efficacies of Dystaenia takeshimana Methanol Extract in a Cell-free System
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The aims of the current study were to examine the antioxidant capacity and the anti-wrinkle and whitening efficacies of Dystaenia takeshimana methanol extract (DTME) in a cell-free system. According to the results, total polyphenolics and flavonoids in DTME were 383.9 TAE mg/g and 275.8 RE mg/g, respectively. The electrondonating ability of DTME at a concentration of 1,000 μg/mL was 96.1% and the results of calculation showed that the IC50 value of free radical was 257.4 μg/mL. Inhibition of collagenase, elastase, and tyrosinase activity by DTME at 1,000 μg/mL was 65.0%, 60.3%, and 71.0%, respectively. The results of calculation showed that the IC50 values of collagenase, elastase, and tyrosinase activities were 496.4 μg/mL, 758.0 μg/mL, and 138.3 μg/mL, respectively, similar to or even superior to that of the ascorbic acid or arbutin positive control (448.3 μg/mL, over 1,000 μg/mL, and 175.3 μg/mL, respectively).
Abstract
The aims of the current study were to examine the antioxidant capacity and the anti-wrinkle and whitening efficacies of Dystaenia takeshimana methanol extract (DTME) in a cell-free system. According to the results, total polyphenolics and flavonoids in DTME were 383.9 TAE mg/g and 275.8 RE mg/g, respectively. The electrondonating ability of DTME at a concentration of 1,000 μg/mL was 96.1% and the results of calculation showed that the IC50 value of free radical was 257.4 μg/mL. Inhibition of collagenase, elastase, and tyrosinase activity by DTME at 1,000 μg/mL was 65.0%, 60.3%, and 71.0%, respectively. The results of calculation showed that the IC50 values of collagenase, elastase, and tyrosinase activities were 496.4 μg/mL, 758.0 μg/mL, and 138.3 μg/mL, respectively, similar to or even superior to that of the ascorbic acid or arbutin positive control (448.3 μg/mL, over 1,000 μg/mL, and 175.3 μg/mL, respectively).
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