비접촉안압계와 초음파 각막두께측정계를 이용하여 측정한 중심각막두께의 비교 분석
Comparison of Central Corneal Thickness Measured by Tono-pachymetry and Ultrasound Pachymetry
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목적: 중심각막두께(central corneal thickness [CCT]) 측정 기능이 탑재된 비접촉안압계(Tono-pachymetry)와 초음파 각막두께측정계(ultrasound pachymetry [USP])를 이용하여 CCT를 측정하고 비교하여 Tono-pachymetry의 유용성에 대해서 알아보고자 하였다. 대상과 방법: 90안을 대상으로 Tono-pachymetry와 USP를 이용하여 측정한 CCT를 비교하고 기기 간 측정값의 상관관계를 분석하였다. CCT에 따라 두 기기 측정값의 차이(△CCT=tono-pachymetry-USP)가 달라지는 것을 보기 위해 전체 대상안을 USP로 측정한 CCT를 기준으로 가장 얇은 환자부터 세 군으로 분류하여 비교 분석하였다. 결과: Tono-pachymetry로 측정한 CCT는 USP를 이용하여 측정한 CCT보다 얇았다(523.26 ± 32.93 vs. 527.08 ± 37.33 μm, p=0.020). 두 결과값은 높은 양의 상관관계를 보였다(r=0.912, p<0.001). 세 군의 분석 결과, Tono-pachymetry와 USP로 측정한 CCT의 차이는 group 1 5.40 ± 12.13 μm, group 2 -6.37 ± 15.07 μm, group 3 -10.50 ± 14.39 μm로 세 군 간의 유의한 차이를 보였다(p<0.001). 결론: Tono-pachymetry로 측정한 CCT는 USP의 측정값에 비해서 평균적으로는 얇게 측정되었으나, 중심각막이 얇을수록 두껍게 측정되고, 중심각막이 두꺼울수록 얇게 측정되는 경향을 보였다.
Abstract
Purpose: We compared the accuracy of central corneal thickness (CCT) measurements according to CCT measured by noncontact Tono-pachymetry and ultrasound pachymetry (USP). Methods: CCT was measured in 90 eyes of 90 subjects by two optometrists. The CCT measurements were compared and the correlations between the measurements were analyzed. To evaluate whether the measurements varied depending on CCT, the subjects were classified into three groups according to CCT (group 1: thin thickness group; group 2: medium thickness group; and group 3: thick thickness group). The differences in CCT obtained by the two devices (△CCT = Tono-pachymetry-USP) were compared and analyzed among the three groups. Results: The average CCT measurements by Tono-pachymetry and USP were 523.26 ± 32.93 μm and 527.08 ± 37.33 μm, respectively. CCT by Tono-pachymetry was significantly thinner than by USP (△CCT= -3.82 ± 15.34, p = 0.020). The two measurements were strongly correlated (r = 0.912, p < 0.001). The △CCT values were 5.40 ± 12.13 μm in group 1, -6.37 ± 15.07 μm in group 2, and -10.50 ± 14.39 μm in group 3 (p < 0.001). Conclusions: CCT measured by tono-pachymetry was thinner on average compared to the value measured by USP and the differences in measurements between the two devices were different according to CCT. The thinner the CCT, the thicker the measurement, and the thicker the CCT, the thinner the measurement. Therefore, this trend should be considered when interpreting tono- pachymetry results in clinical practice.
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