이중샤임플러그, 전안부 빛간섭단층촬영계 및 초음파 각막두께측정계를 이용한 각막두께의 비교
Corneal Thickness Measured by Dual Scheimpflug, Anterior Segment Optical Coherence Tomography, and Ultrasound Pachymetry
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목적: 이중샤임플러그 전안부사진기(Galilei), 전안부 빛간섭단층촬영계 및 초음파 각막두께측정계를 이용하여 중심각막두께의 측정치를 비교하고자 한다. 대상과 방법: 정상인 20명 40안을 대상으로 이중샤임플러그, 전안부 빛간섭단층촬영계, 그리고 초음파 각막두께측정계로 측정된 중심각막두께를 비교하고 상관관계를 알아보았다. 결과: 이중샤임플러그, 전안부 빛간섭단층촬영계, 초음파 각막두께측정계를 이용하여 측정한 중심각막두께는 각각 538.10 ± 31.36 μm,536.20 ± 31.21 μm, 541.93 ± 34.93 μm였고 초음파 각막두께측정계가 이중샤임플러그, 전안부 빛간섭단층촬영계보다 유의하게 두껍게 측정되었다(p=0.017, p=0.001). 이중샤임플러그와 전안부 빛간섭단층촬영계에 의해 측정된 중심각막두께는 유의한 차이가 없었다(p=0.054). 세 검사는 유의한 상관관계를 보였다(r˃0.900, p<0.001). 결론: 세 검사 사이에 유의한 상관관계가 있었지만, 초음파 각막두께측정계에 의해 측정된 중심각막두께가 이중샤임플러그, 전안부빛간섭단층촬영계의 의한 측정값보다 유의하게 두껍게 측정되어 결과 해석 시 이에 대한 고려가 필요할 것으로 생각한다.
Abstract
Purpose: To compare central corneal thickness (CCT) as measured by dual rotating Scheimpflug camera (Galilei), anterior segment optical coherence tomography (AS-OCT), and ultrasound pachymetry (USP). Methods: The measurements of CCT using a dual rotating Scheimpflug camera, AS-OCT, and USP in 40 eyes of 20healthy subjects were compared. Results: The average measurements of CCT by dual rotating Scheimpflug camera, AS-OCT, and USP were 538.10 ±31.36 μm, 536.20 ± 31.21 μm, and 541.93 ± 34.93 μm, respectively. The CCT measurement by USP was statistically significantly thicker than by the dual rotating Scheimpflug camera and AS-OCT (p = 0.017, p = 0.001, respectively). There was no significant difference between the dual rotating Scheimpflug camera and AS-OCT (p = 0.054). A significant linear correlation was observed between the dual rotating Scheimpflug camera, the AS-OCT, and the USP (r > 0.900, p < 0.001). Conclusions: The results of the 3 methods have significant correlation with each other, but the measurement by USP was significantly thicker than the dual rotating Scheimpflug camera and AS-OCT. Therefore, CCT should be interpreted in the context of the instrument used.
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