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비만 중년 여성의 유산소운동에 따른 혈중 렙틴과 비만지표 및 심폐체력의 상관

Correlations of blood leptin and obesity indices and cardiorespiratory fitness according to 12-week aerobic exercise in premenopausal women

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안의수, 이지영, 박수현, 한태경, 강현식. 비만 중년 여성의 유산소운동에 따른 혈중 렙틴과 비만지표 및 심폐체력의 상관성. 운동과학, 제 15권 제3호, 251-258, 2006. 본 연구의 목적은 12주 유산소성 운동에 의한 렙틴의 감소와 비만지표 및 심폐체력의 개선과의 연관성을 분석하여, 렙틴의 감소에 비만지표 및 심폐체력 수준의 개선이 가지는 영향력을 검증하는 것이었다. 본 연구의 연구대상자는 의학적으로 건강한 폐경 전 복부비만 여성 46명으로 하였다. 본 연구 결과, 12주 유산소성 운동에 의해 혈중 렙틴 농도와 비만지표는 유의한 감소를 보이는 것으로 나타났고, 심폐체력은 유의하게 증가하는 것으로 나타났다. 그리고 측정변인들의 변화 값을 이용한 pearson's의 상관분석 결과, 혈중 렙틴의 변화는 모든 변인들과 유의한 상관을 가지는 것으로 나타났으며, 특히 심폐체력과 가장 큰 음의 상관관계를 가지는 것으로 나타났다. 또한 혈중 렙틴 농도 변화에 대한 예측 독립인자 분석을 위한 다중회귀분석에서 심폐체력만이 혈중 렙틴 농도 변화를 설명하는 독립예측인자인 것으로 나타났다. 결론적으로 심폐체력의 개선은 혈중 렙틴 농도 감소와 밀접한 관련을 가지고 있는 것으로 나타났으며, 렙틴 저항의 감소가 체지방의 감소와 관련이 있음을 감안할 때, 심폐체력 개선에 의한 혈중 렙틴 농도의 감소에 의해 비만이 치료될 수 있음을 제시하고 있다고 사료된다.

Abstract

Ann, E.S., Lee, J.Y., Park, S.H., Han, T.K., Kang, H.S. Correlations of blood leptin and obesity indices and cardiorespiratory fitness according to 12-week aerobic exercise in premenopausal women. Exercise Science, 15(3), 251-258, 2006. The purpose of the study was to investigate effect of obesity indices and cardiorespiratory fitness on decrease of blood leptin concentration by analysing correlations of blood leptin concentration, obesity indices, and cardiorespiratory fitness according to 12-week aerobic exercise. A total of 46 apparently healthy premenopausal mid-life women were recruited via fly and local advertise- ment. 12-week aerobic exercise was executed dance exercise to 50-70% of VO2max, 60min/day, and 3 times/week. Paired t-test of variance showed that obesity indices, blood leptin concentration, cardiorespiratory fitness had significant difference according to 12-week aerobic exercise. Also, pearson's correlation of all variance had significant correlations. Especially, decrease of blood leptin concentration had greatest negative correlation with improvement of cardiorespiratory fitness. And a stepwise regression analysis showed that improvement of cardiorespi- ratory fitness independently explained individual variation in decrease of blood leptin concentration. The current findings of the study suggest that improvement of cardiorespiratory fitness have strong relation with decrease of blood leptin concentration, and it may be metabolic process on obesity therapy by improvement of cardiorespiratory fitness.

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