활동적 비디오 게임을 활용한 신체활동이 고지방식이 후혈관기능에 미치는 영향
Effects of an active video game on vascular function after a high fat meal.
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본 연구의 목적은 고지방 식이 섭취 후 활동적 비디오 게임을 이용한 신체활동이 혈관기능에 미치는 영향에 대해 알아보는 데 있다. 피험자는 정상체중의 건강한 성인 16명(남자 9명, 여자 7명, 나이 24±4세, 체질량지수 22.4±2.1 ㎏/㎡)을 대상으로 하였으며 모든 피험자가 신체활동 처치와 통제 처치에 모두 참여하는 cross-over design으로 설계하였다. 고지방식이는 총 1,257 kcal의 햄버거를 섭취하였다. 신체활동은 고지방 식이 섭취 후 30분에 50분간 활동적 비디오 게임(50분)을 실시하였다. 종속변인으로 혈중지질(총 콜레스테롤, 중성지방, 저밀도 지단백 콜레스테롤, 고밀도 지단백 콜레스테롤), 혈압, 혈관기능(상완동맥 혈류 의존성 혈관 이완능, 경동맥-대퇴동맥 맥파전파속도)을 측정하였으며, 측정시기는 고지방 식이 전, 고지방 식이 후 3시간, 고지방 식이 후 5시간으로 하였다. 연구 결과, 일시적 고지방 식이는 활동적 비디오 게임 처치와 통제처치 모두 혈중 중성지방 농도를 유의하게 증가시켰으나(시기 효과, p=0.001) 두 처치 간 유의한 차이는 없었다. 혈관내피세포 기능은 고지방 식이 후 3시간에 통제처치에서는 감소된 반면(사전：9.32±2.86 %, 식후 3시간：8.13±3.56 %), 활동적 비디오 게임 처치에서는 혈관내피세포 기능이 개선되는 경향을 보였으나 통계적으로 유의한 차이는 나타나지 않았다(사전：8.74±3.13 %, 식후 3시간：9.21±3.40 %). 경동맥-대퇴동맥 맥파전파속도는 고지방 식이 후 변화를 보이지 않았으며 처치 간 차이 또한 나타나지 않았다. 본 연구의 결과를 종합해 보면, 고지방 식이 후 활동적 비디오 게임의 실시는 혈중 중성지방 증가를 유의하게 감소시키지 못하였으며, 고지방식이로 인한 혈관내피세포 기능 및 동맥경직도 변화를 개선시키지 못하였다. 따라서 건강한 성인에게 활동적 비디오 게임은 고지방 식이에 따른 혈관 기능 변화에 있어 운동의 보호적 효과를 얻기에 운동강도 및 운동량이 부족한 것으로 사료된다.
Abstract
A high fat meal transiently decreases vascular function, while acute aerobic exercise improves vascular function. Active video games are now highly popular and play a role in promoting physical activity. Although studies suggest that acute aerobic exercise attenuates high fat meal induced vascular dysfunction, but it is not clear whether an active video game could attenuate vascular dysfunction after a high fat meal. We tested the hypothesis that an active video game would partially prevent the unfavorable effect of vascular function by high fat meal in young adults. Using a randomized cross over design, sixteen healthy young subjects (male 9, female 7；age 24±4 yrs, BMI 22.4±2.1 ㎏/㎡) were assigned to both an active video game(AVG：50 minutes) and a seated rest(CON) after a high fat meal. Lipid profiles, blood pressure, and vascular function measured at baseline, 3 and 5 hours after a high fat meal. Vascular function was measured by endothelial function(brachial artery flow mediated dilation；FMD) and arterial stiffness(carotid-femoral pulse wave velocity；C-F PWV). Blood triglyceride levels were significantly increased in two treatment conditions after a high fat meal and did not significantly different between two groups(AVG：74.06±43.36, 160.63±106.20, 126.81±91.41 mg/dl；CON：70.06±38.67, 168.38±85.89, 128.75±87.26 mg/dl, p=0.878). FMD was decreased in the CON (9.32±2.86 to 8.13±3.56 %), but increased in the AVG (8.74±3.13 % to 9.21±3.40 %) at 3 hr after a high fat meal. However, there was no significantly different between two groups (p=0.189). C-F PWV was similarly decreased in two treatment conditions after a high fat meal and did not significantly different between two groups (AVG：6.39±1.12, 6.08±0.94, 6.38±1.07 m/s；CON：6.34±0.85, 6.19±0.89, 6.28±1.01 m/s, p=0.483). These findings show that a high fat meal caused a temporary decrease in endothelial function, but these decreases were not significantly attenuated in the group with active video game compare to the group with seated rest. Therefore, active video game may not have a cardioprotective effect in young healthy adults exposed to acute high fat meal.
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