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일주일간의 간헐적 좌식차단의 혈관기능 개선 효과

Seven Days Breaking Up Prolonged Sitting Improves Systemic Endothelial Function in Sedentary Men

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초록

PURPOSE: To examine the cumulative (7 days) effect of breaking up prolonged sitting on systemic endothelial function in sedentary men. METHODS: Thirty sedentary men (33.93±5.72 year) participated in two randomized 7 days sitting trial (Sit group (control) vs. Breaks group). The protocol of Breaks group is as follows: 4-min of moderate-intensity marching in place (walking) every 1hr during business hour (total: 8 breaks/day). Assessment of brachial artery endothelial function using flow-mediated dilation (FMD) and arterial stiffness indices (augmentation index, arterial pressure and pulse wave velocity) were measured before and after 7 days treatment. RESULTS: Brachial artery FMD significantly increased after 7 days breaking up prolonged sitting treatment (Breaks groups, 9.65±2.61 to 9.62±2.6%) compared with 7 days prolonged sitting (Sit group, 8.37±3.41 to 10.11±3.75%) (interaction effect, p=.004). Arterial pressure (AP) significantly increased after treatment (Breaks group, 2.75±2.19 to 2.38±1.63 mmHg, p=.002) in Sit group but there was no change (Sit group, 1.00±3.18 to 2.50±9.23 mmHg) in Breaks groups (interaction effect, p=.008). CONCLUSIONS: These finding show that 7 days regular breaking up prolonged sitting improve in FMD, compared with prolonged sitting. Therefore, regular breaking up prolonged sitting may improve systemic endothelial vascular function in sedentary men.

Abstract

PURPOSE: To examine the cumulative (7 days) effect of breaking up prolonged sitting on systemic endothelial function in sedentary men. METHODS: Thirty sedentary men (33.93±5.72 year) participated in two randomized 7 days sitting trial (Sit group (control) vs. Breaks group). The protocol of Breaks group is as follows: 4-min of moderate-intensity marching in place (walking) every 1hr during business hour (total: 8 breaks/day). Assessment of brachial artery endothelial function using flow-mediated dilation (FMD) and arterial stiffness indices (augmentation index, arterial pressure and pulse wave velocity) were measured before and after 7 days treatment. RESULTS: Brachial artery FMD significantly increased after 7 days breaking up prolonged sitting treatment (Breaks groups, 9.65±2.61 to 9.62±2.6%) compared with 7 days prolonged sitting (Sit group, 8.37±3.41 to 10.11±3.75%) (interaction effect, p=.004). Arterial pressure (AP) significantly increased after treatment (Breaks group, 2.75±2.19 to 2.38±1.63 mmHg, p=.002) in Sit group but there was no change (Sit group, 1.00±3.18 to 2.50±9.23 mmHg) in Breaks groups (interaction effect, p=.008). CONCLUSIONS: These finding show that 7 days regular breaking up prolonged sitting improve in FMD, compared with prolonged sitting. Therefore, regular breaking up prolonged sitting may improve systemic endothelial vascular function in sedentary men.

참고문헌 (44)

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