자귀나무(A. julibrissin) 수피 추출물의 생리활성
The Physiological Activities of Bark Extract of Albizia julibrissin
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초록
Three bark extracts of Albizia julibrissin were prepared using water (AW), 70% (v/v) ethanol (AE), and hot water (AHW). Organic solvent fractions were analyzed for total flavonoids and polyphenols, antioxidant activities, and inhibitory activities against xanthine oxidase. Total flavonoid and polyphenol contents of the AHW extract were 8.57 mg/g and 108.67 mg/g, respectively. The SOD-like activities of all extracts, assayed at 1.0 mg/mL, were 10.46-16.73%. The nitrite-scavenging ability of the AHW extract, assayed at pH 1.2, was 60.82%, and the IC50 value was 770.18 μg/mL. The electron-donating ability of the AHW extract, at 0.3 mg/mL, was 92.30%; the IC50 values of the AW and AHW extracts were 31.31 μg/mL and 36.22 μg/mL, respectively; thus higher than that of ascorbic acid (39.06 μg/mL). Xanthine oxidase inhibition by the AHW extract, at 1.0 mg/mL, was 94.05%. These results indicate that the AHW of A. julibrissin has potential as a natural antioxidant, for addition to foods and nutraceuticals.
Abstract
Three bark extracts of Albizia julibrissin were prepared using water (AW), 70% (v/v) ethanol (AE), and hot water (AHW). Organic solvent fractions were analyzed for total flavonoids and polyphenols, antioxidant activities, and inhibitory activities against xanthine oxidase. Total flavonoid and polyphenol contents of the AHW extract were 8.57 mg/g and 108.67 mg/g, respectively. The SOD-like activities of all extracts, assayed at 1.0 mg/mL, were 10.46-16.73%. The nitrite-scavenging ability of the AHW extract, assayed at pH 1.2, was 60.82%, and the IC50 value was 770.18 μg/mL. The electron-donating ability of the AHW extract, at 0.3 mg/mL, was 92.30%; the IC50 values of the AW and AHW extracts were 31.31 μg/mL and 36.22 μg/mL, respectively; thus higher than that of ascorbic acid (39.06 μg/mL). Xanthine oxidase inhibition by the AHW extract, at 1.0 mg/mL, was 94.05%. These results indicate that the AHW of A. julibrissin has potential as a natural antioxidant, for addition to foods and nutraceuticals.
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