으름(Akebia quinata) 부위별 추출물의 생리활성 평가
Evaluation of physiological activities of extracts from different parts of Akebia quinata
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In this study, we investigated the antioxidant and inhibitory activities of different parts extracts of Akebia quinata. The extraction yield was extract from Akebia quinata fruit by hot water (AFW) slightly highest 25.23±0.21%, in all parts exceeded 20%. Antioxidant activity tests showed superior activity in the leaves, suggesting that total phenolic and flavonoid compounds contributed to this effect. 1,1-Diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azino-bis (3-ethylbenzothiazoline-6- sulfonic acid) (ABTS+) radical scavenging activities, IC50 values of 41.67±0.62 and 36.22±0.10 μ g/mL were determined for the extract from Akebia quinata leaf by 70% ethanol (ALE), respectively. The xanthine oxidase and tyrosinase inhibition effect IC50 values of 371.62±2.06 and 196.16±0.98 μg/mL were determined for the extract from Akebia quinata leaf by hot-water (ALW) and extract from Akebia quinata leaf by 70% ethanol (ALE), respectively. The reducing power showed an increase in effectiveness as the concentration of the extract increased, AFW was the highest with 25.23±0.21%. The results suggest that the Akebia quinata extract possess potent antioxidant properties.
Abstract
In this study, we investigated the antioxidant and inhibitory activities of different parts extracts of Akebia quinata. The extraction yield was extract from Akebia quinata fruit by hot water (AFW) slightly highest 25.23±0.21%, in all parts exceeded 20%. Antioxidant activity tests showed superior activity in the leaves, suggesting that total phenolic and flavonoid compounds contributed to this effect. 1,1-Diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azino-bis (3-ethylbenzothiazoline-6- sulfonic acid) (ABTS+) radical scavenging activities, IC50 values of 41.67±0.62 and 36.22±0.10 μ g/mL were determined for the extract from Akebia quinata leaf by 70% ethanol (ALE), respectively. The xanthine oxidase and tyrosinase inhibition effect IC50 values of 371.62±2.06 and 196.16±0.98 μg/mL were determined for the extract from Akebia quinata leaf by hot-water (ALW) and extract from Akebia quinata leaf by 70% ethanol (ALE), respectively. The reducing power showed an increase in effectiveness as the concentration of the extract increased, AFW was the highest with 25.23±0.21%. The results suggest that the Akebia quinata extract possess potent antioxidant properties.