음나무(Kalopanax pictus) 수피 추출물의 항산화 활성에 관한 연구
Antioxidant Activities of Bark Extracts from Kalopanax pictus
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초록
This study was carried out to compare the antioxidant activities of Kalopanax pictus bark extract. The flavonoid and polyphenol contents of KBW (K. pictus bark water extract) were 17.13 mg/g and 27.14 mg/g, and KBE (K. pictus bark ethanol extract) were 15.80 mg/g and 21.36 mg/g, respectively. The tyrosinase inhibition of KBE was 16.08% and KBW was 13.15% at 2,000 μg/mL. In the results of xanthine oxidase inhibition, the half maximal inhibitory concentration (IC_50) of KBW (142.59 μg/mL) represents an excellent activity compared to the ascorbic acid (192.50 ㎍/mL)). The 1,1-diphenyl-2-picryl hydrazyl (DPPH) radical scavenging activity, IC_50 of KBW and KBE were 13.62 μg/mL, respectively, and 15.70 μg/mL, it was significantly 2.2∼2.5 higher compared to the ascorbic acid (34.97 μg/mL). The superoxide dismutase (SOD)-like activity of KBW was 63.63% (IC_50 1,554.90 μg/mL). The nitrite scavenging ability of KBW was 74.77% (IC_50 1,000.00 μg/mL) at pH 1.2 and 61.62% (1,264.56 μg/mL) at pH 3.0. This suggest that K. pictus bark can be useful physiological source for the development of cosmetic materials.
Abstract
This study was carried out to compare the antioxidant activities of Kalopanax pictus bark extract. The flavonoid and polyphenol contents of KBW (K. pictus bark water extract) were 17.13 mg/g and 27.14 mg/g, and KBE (K. pictus bark ethanol extract) were 15.80 mg/g and 21.36 mg/g, respectively. The tyrosinase inhibition of KBE was 16.08% and KBW was 13.15% at 2,000 μg/mL. In the results of xanthine oxidase inhibition, the half maximal inhibitory concentration (IC_50) of KBW (142.59 μg/mL) represents an excellent activity compared to the ascorbic acid (192.50 ㎍/mL)). The 1,1-diphenyl-2-picryl hydrazyl (DPPH) radical scavenging activity, IC_50 of KBW and KBE were 13.62 μg/mL, respectively, and 15.70 μg/mL, it was significantly 2.2∼2.5 higher compared to the ascorbic acid (34.97 μg/mL). The superoxide dismutase (SOD)-like activity of KBW was 63.63% (IC_50 1,554.90 μg/mL). The nitrite scavenging ability of KBW was 74.77% (IC_50 1,000.00 μg/mL) at pH 1.2 and 61.62% (1,264.56 μg/mL) at pH 3.0. This suggest that K. pictus bark can be useful physiological source for the development of cosmetic materials.
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