비접촉경면현미경, 이중샤임플러그 전안부사진기, 초음파각막두께측정계를 이용해 측정한 중심각막두께의 비교
Central Corneal Thickness Measured by Noncontact Specular Microscopy, Dual Rotating Scheimpflug Camera and Ultrasound Pachymetry
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목적: 비접촉경면현미경, 이중샤임플러그전안부 사진기 및 초음파 각막두께측정계를 이용하여 중심각막두께의 측정치를 비교하고자하였다. 대상과 방법: 정상인 70명 70안을 대상으로 비접촉경면현미경, 이중샤임플러그전안부 사진기 그리고 초음파 각막두께측정계로 측정한 중심각막두께를 비교하고 상관관계를 알아보았다. 결과: 비접촉경면현미경, 이중샤임플러그전안부 사진기 및 초음파 각막두께측정계를 이용하여 측정한 중심각막두께는 각각 567.70 ± 31.21 μm, 557.84 ± 26.29 μm, 553.31 ± 29.69 μm로 비접촉경면현미경이 가장 두껍게 측정되었고 초음파 각막두께측정계가 가장얇게 측정되었으며, 각 측정치 사이에 통계적으로 유의한 차이를 보였다(p＜0.05). 이 중 비접촉경면현미경은 초음파 각막두께측정계보다 유의하게 두껍게 측정되었다(p＜0.05). 세 검사는 높은 양의 상관관계를 보였다(r＞0.900, p＜0.001). 결론: 비접촉경면현미경에 의해 측정된 중심각막두께는 초음파각막두께측정계에 의해 측정된 중심각막두께보다 유의하게 두껍게 측정되어 결과 해석 시 이에 대한 고려가 필요할 것으로 생각된다. 또한 이중샤임플러그전안부 사진기로 측정한 중심각막두께가 초음파각막두께측정계로 측정한 값에 좀 더 유사한 값을 나타내며 정상안의 중심각막두께 측정에 이중샤임플러그전안부 사진기가 비접촉경면현미경보다 초음파 각막두께측정계를 대체할 수 있는 좀 더 유용한 방법이라 생각된다.
Abstract
Purpose: To compare central corneal thickness (CCT) as measured using noncontact specular microscopy (NCSM), dual rotating Scheimpflug camera (Galilei®), and ultrasound pachymetry (USP). Methods: The measurements of CCT using NCSM, dual rotating Scheimpflug camera and USP in 70 eyes of 70 healthy subjects were compared. Results: The average measurements of CCT using NCSM, dual rotating Scheimpflug camera, and USP were 567.70 ± 31.21 μm, 557.84 ± 26.29 μm, and 553.31 ± 29.69 μm, respectively. The CCT measurement using NCSM was statistically significantly thicker than when measured using USP (p < 0.05). There was no significant difference between the NCSM and dual rotating Scheimpflug camera (p = 0.138). Additionally, there was no significant difference between the dual rotating Scheimpflug camera and USP (p = 0.656). A significant linear correlation was observed among the NCSM, dual rotating Scheimpflug camera, and USP (r > 0.900, p < 0.001). Conclusions: The results of the 3 methods were significantly correlated but the measurement using NCSM was significantly thicker than when using USP. CCT measurements of healthy eyes using dual rotating Scheimpflug camera were more correlated with USP than NCSM. The CCT measurements using dual rotating Scheimpflug camera is a better alternative for USP than NCSM.
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