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PEG(Polyethylene glycol) antiglobulin test를 이용한 항체선별검사의 평가

Evaluation of the Polyethylene Glycol Antiglobulin Test for Routine Antibody Screening Test

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주제분류기타자연과학

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Abstract

The polyehylene glycol antiglobulin test for detection of red cell antibodies was compared with a proven, highly sensitive test system using bovine serum albumin(BSA). All specimens recived in the blood bank over 1-year period for transfusion requests or preoperation patients for roution antibody screening test. The sera of 73 of 6734 patients had detected antibodies. Nine clinically significant antibodies (1-anti-Jka, 2-E, 1-E,c, 3-c, 2-Lea) and four antibodies(1 -anti-Jka,Fyb, 1-C, 1-Fyb, 1-warm auto) demonstrated inconclusive PEG method. Eight patients had multiple antibodies. We used polyspecific antihuman globulin serum but 1.23% nonspecific reactions by PEGmethod.

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