Investigation of Red Cell Antiobody Screening Tests Gyeonggi Areas
2
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
Red blood cell (RBC) alloimmunization results from genetic disparity of RBC antigens betweendonor and recipients. The discrepancy of RBC antibody screening test occurs when the results ofred cell tests do not agree with those of the serum test. In order to select the proper blood units fortransfusion, clarification of the cause of discrepancies is essential. The RBC antibody screening testis an easy, quick, and reliable method for detection of clinically significant antibodies. Antibodyscreening and identification is recommended prior to transfusion to determine whether there isblood group incompatibility. We reported that phenotyping for E, D, M, E+c, and C+e antibodyscreening test should be extended. Therefore, these results indicate that anti-D and anti-Ealloantibodies were major risk factors for haemolytic disease of the newborn or delayed haemolytictransfusion reactions in this study population. We suggested that its antibody screening beadapted to blood safety interventions. Targeted screening of selected recipients at risk offers lessvalue than universal antibody screening, and more research is needed to determine the realincidence of this national condition.
Abstract
Red blood cell (RBC) alloimmunization results from genetic disparity of RBC antigens betweendonor and recipients. The discrepancy of RBC antibody screening test occurs when the results ofred cell tests do not agree with those of the serum test. In order to select the proper blood units fortransfusion, clarification of the cause of discrepancies is essential. The RBC antibody screening testis an easy, quick, and reliable method for detection of clinically significant antibodies. Antibodyscreening and identification is recommended prior to transfusion to determine whether there isblood group incompatibility. We reported that phenotyping for E, D, M, E+c, and C+e antibodyscreening test should be extended. Therefore, these results indicate that anti-D and anti-Ealloantibodies were major risk factors for haemolytic disease of the newborn or delayed haemolytictransfusion reactions in this study population. We suggested that its antibody screening beadapted to blood safety interventions. Targeted screening of selected recipients at risk offers lessvalue than universal antibody screening, and more research is needed to determine the realincidence of this national condition.
참고문헌 (18)
- 신정원, "Unexpected red cell antibody detection by conditional combination of LISS", Coombs and NaCl, Blood Research, pp.2013, 48(3)[DOI]
- 이규형, "비예기 항체 선별 검사의 예민도에 영향을 미치는 인자 연구", 대한임상검사과학회지, 30(2), pp.193~198 (1998), 대한임상검사과학회
- 이종숙, "PEG(Polyethylene glycol) antiglobulin test를 이용한 항체선별검사의 평가", 대한임상검사과학회지, 30(2), pp.214~221 (1998), 대한임상검사과학회
- Pathak S, "Type and screen policy in the blood bank : is AHG cross-match still required? a study at a multispeciality corporate hospital in India", Asian J Transfus Sci, 5, pp.153~156 (2011)
- Natukunda B, "Prevalence and specificities of red blood cell alloantibodies in transfused Ugandans with different diseases", Vox Sang, 98, pp.167~171 (2010)
- Enko D, "Frequencies and specificities of"enzyme-only"detected erythrocyte alloantibodies in patients hospitalized in austria : is an enzyme test required for routine red blood cell antibody screening?", J Blood Transfus, 2014, pp.532919~ (2014)
- Yousuf R, "Incidence of red cell alloantibody among the transfusion recipients of universiti Kebangsaan Malaysia medical centre", Indian J Hematol Blood Transfus, 29, pp.65~70 (2013)
- Song DH, "Frequency and distribution of unexpected antibodies of Koreans", Korean J Blood Transfus, 9, pp.191~200 (1998)
- Broadberry RE, "The incidence and significance of anti-"Mia"in Taiwan", Transfusion, 34, pp.349~352 (1994)
- Branch DR, "Solving the dilemma of prevention of red cell alloimmunization", Immunotherapy, 4, pp.903~905 (2012)
- Xu P, "Prevalence, specificity and risk of red blood cell alloantibodies among hospitalised Hubei Han Chinese patients", Blood Transfus, 12, pp.56~60 (2014)
- Winters JL, "RBC alloantibody specificity and antigen potency in Olmsted County, Minnesota", Transfusion, 41, pp.1413~1420 (2001)
- Holusková I, "Erythrocyte alloimmunization in pregnant women, clinical importance and laboratory diagnostics", Ceska Gynekol, 78, pp.89~99 (2013)
- Sood R, "Detection of alloimmunization to ensure safer transfusion practice", Asian J Transfus Sci, 7, pp.135~139 (2013)
- Fayek MH, "Role of gel test and flow cytometry in diagnosis of Coombs' negative autoimmune haemolytic anaemia", Int J Lab Hematol, 34, pp.311~319 (2012)
- Jan RH, "Incidence of alloantibodies in transfused patients in Eastern Taiwan", Tzu Chi Med J, 21, pp.66~69 (2009)
- Heathcote DJ, "Novel antibody screening cells, MUT+Mur kodecytes, created by attaching peptides onto red blood cells", Transfusion, 50, pp.635~641 (2010)
- Wu KH, "Hydrops foetalis caused by anti-Mur in first pregnancy—a case report", Transfus Med, 12, pp.325~327 (2002)