8주간의 유산소운동과 폴리페놀 섭취가 경계성 고혈압자의 안정시와 운동중 심혈관반응과 혈관내피기능에 미치는 영향
Effects of 8-week Aerobic Exercise and Polyphenol Intake on Cardiovascular Response and Vascular Endothelial Function in Pre-hypertensive Men at Rest and during Exercise
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[목적] 이 연구의 목적은 8주간의 유산소운동과 폴리페놀 섭취가 경계성 고혈압자의 신체구성, 안정시와 운동중 심혈관반응, 혈관내피기능, 그리고 체력에 미치는 영향을 규명하는 것이다. [방법] 20~30대 남성 경계성 고혈압자 28명을 유산소운동+폴리페놀 섭취 집단(EX+Polyphenol 집단)과 유산소운동+위약섭취 집단(EX+Placebo 집단)에 14명씩 무선 할당하였다. EX+Polyphenol 집단의 대상자는 8주간 주 3회, 회당 30분, 예비심박수의 65% 강도로 유산소운동을 실시하였고, 처치 기간 중 매일 오전 폴리페놀(포도씨 추출물300mg)을 섭취하였다. EX+Placebo 집단의 대상자는 동일하게 유산소운동을 실시하였고, 폴리페놀 대신 위약을 섭취하였다. 사전검사와 사후검사에서 각 종속변인을 측정한 후 집단 간에, 그리고 시기 간에 비교 분석하였다. [결과] 이 연구의 주요 결과는 다음과 같다. 1) 안정시 EX+Polyphenol 집단의 SBP와 MAP가 유의하게 감소되었고, EX+Placebo 집단의 MAP도 유의하게 감소되었다. 2) 핸드그립 운동중 EX+Polyphenol 집단의 CO가 유의하게 증가되었고, DBP, MAP, 그리고 TPR이 유의하게 감소되었다. 핸드그립 운동중 EX+Placebo 집단의 CO가 유의하게감소되었고, DBP와 TPR이 유의하게 증가되었다. 3) 혈관내피기능과 관련하여 EX+Polyphenol 집단의 %FMD가유의하게 증가되었다. 4) EX+Polyphenol 집단과 EX+Placebo 집단의 윗몸일으키기 기록이 유의하게 증가되었고, EX+Polyphenol 집단의 앉아윗몸앞으로굽히기 기록이 사후검사 시점에서 EX+Placebo 집단에 비하여 유의하게 높았다. [결론] 이상의 결과를 통하여 8주간 실시한 유산소운동이 20~30대 남성 경계성 고혈압자의 신체구성, 안정시와 운동중 심혈관반응, 그리고 체력에 긍정적인 영향을 미쳤으며, 유산소운동과 병행하여 처치한 폴리페놀 섭취가 안정시와운동중 혈압 감소, 그리고 혈관내피기능의 향상에 더 크게 공헌했다고 결론지을 수 있다.
Abstract
PURPOSE The purpose of this study was to investigate the effects of 8-week aerobic exercise and polyphenol intake on body composition, cardiovascular response, vascular endothelial function, and physical fitness at rest and during exercise in prehypertensive men. METHODS The study included twenty-eight males in their 20-30 years of age with prehypertension. Participants in the aerobic exercise + polyphenol intake group (EX + PP; n = 14) performed aerobic exercise three sessions/week, 30 min/session, at 65% of the heart rate reserve, and consumed polyphenol (grape seed extract 300 mg) for 8 weeks. Participants in the aerobic exercise + placebo intake group (EX + PL; n = 14) performed the same aerobic exercise; however, they consumed placebo instead of polyphenol. All independent variables were measured at pre-test and post-test, and the data were analyzed. RESULTS The main results of the study were as follows: 1) SBP and MAP at rest decreased significantly in EX + PP, while MAP decreased significantly in EX + PL group. 2) In the EX + PP group, CO increased significantly, whereas DBP, MAP, and TPR decreased significantly during the hand grip exercise. In contrast, CO decreased significantly, while DBP and TPR increased significantly in the EX + PL group during the hand grip exercise. 3) Regarding vascular endothelial function, % FMD increased significantly in EX + PP group. 4) Sit-up increased significantly in both EX + PP and EX + PL groups; however, sit-and-reach in EX + PP group was significantly higher than that in EX + PL group at post-test. CONCLUSIONS The findings of this study showed that the 8-week aerobic exercise would have positive effects on body composition, cardiovascular response, and physical fitness at rest and during exercise in hypertensive men. Additionally, polyphenol intake would contribute more towards reduction of blood pressure at rest and during exercise and improvement of vascular endothelial function.
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