기체/액체 분산계에 의한 다공성 CS/PVA 마스크 시트의 제조와 물리적특성
Preparation and Physical Properties of Porous Mask Sheet Prepared by Dispersion System of Gases in Liquids
1
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
The hydrogels being cross-linked polymer have been widely investigated as a cosmetic delivery system. Porous hydrogel of biopolymer comprise an important class of polymeric matters due to their interesting properties for potential applications including cosmetics. Porous hydrogel have a 3D hydrophilic polymeric structure, and their free spaces can be filled with cosmetic fluids. Since hydrogels are the polymers which swell in presence of water and they entrap cosmetic ingredients within their pores. Through this research, we prepared CS/PVA mask sheet by dispersion system of gases in liquids method. The CS/PVA porous hydrogel mask sheet was produced via gas in liquid dispersions with glutaraldehyde as cross-linker. The carbon dioxide gas that used 1% sodium bicarbonate was applied to produce the porous sponge structure. The morphology such as the pore size and porosity was examined via field emission scanning electron microscopy (FE-SEM). The morphology of the sponge structure showed good pore distribution. The comparison of the swelling results showed the pH dependence of the swelling process. The degree of swelling for 5% lactic acid, distilled water,and 5% sodium hydroxide were 2117%, 1047% and 674%, and the degree of swelling of 95% ethanol was only 89%. The porous CS/PVA mask sheet has good response to change in pH of the external environment. These are scientific evidence for the potentiality in delivery of cosmetic active ingredients. All properties of porous CS/PVA mask sheet were found to be enough to for the desired properties of a cosmetic products.
Abstract
The hydrogels being cross-linked polymer have been widely investigated as a cosmetic delivery system. Porous hydrogel of biopolymer comprise an important class of polymeric matters due to their interesting properties for potential applications including cosmetics. Porous hydrogel have a 3D hydrophilic polymeric structure, and their free spaces can be filled with cosmetic fluids. Since hydrogels are the polymers which swell in presence of water and they entrap cosmetic ingredients within their pores. Through this research, we prepared CS/PVA mask sheet by dispersion system of gases in liquids method. The CS/PVA porous hydrogel mask sheet was produced via gas in liquid dispersions with glutaraldehyde as cross-linker. The carbon dioxide gas that used 1% sodium bicarbonate was applied to produce the porous sponge structure. The morphology such as the pore size and porosity was examined via field emission scanning electron microscopy (FE-SEM). The morphology of the sponge structure showed good pore distribution. The comparison of the swelling results showed the pH dependence of the swelling process. The degree of swelling for 5% lactic acid, distilled water,and 5% sodium hydroxide were 2117%, 1047% and 674%, and the degree of swelling of 95% ethanol was only 89%. The porous CS/PVA mask sheet has good response to change in pH of the external environment. These are scientific evidence for the potentiality in delivery of cosmetic active ingredients. All properties of porous CS/PVA mask sheet were found to be enough to for the desired properties of a cosmetic products.
참고문헌 (21)
- 김계용, , 13, pp.454~460 (1989)
- 김공수, "다공성 키토산 섬유의 제조 및 흡수 특성", 한국키틴키토산학회지, 5, pp.144~151 (2000)
- 김용희, "고분자과학과 기술", pp.544~549 (1994), 한국고분자학회
- 손채영, "화장품 소재로서의 Chitosan", PVA Hydrogel Mask Sheet 제조와 특성평가, 을지대학교 보건대학원, pp.피부관리학과, 2013
- 임재길, "아가로즈-셀룰로오스 하이브리드 신소재의 물리화학적 특성과 의학 및 생활 보건의 적용", 대한구강악안면병리학회지, 32(3), pp.143~160 (2008), 대한구강악안면병리학회
- 호병균, "Chitosan을 이용한 Silymarin의 방출제어", 한국약제학회지, 25, pp.37~46 (1995)
- Chu C, "pH-Sensitive Swelling of a Polyelectrolyte Complex Gel Prepared from Xanthan and Chitosan", Biosci. Biotech. Biochem, 59, pp.717~719 (1995)
- Comoglu T, "Microsponge Delivery Systems", J. Faculty Pharm. Ankara. Univ, 29, pp.75~86 (2002)
- Gammal C, "Anatomy or the skin surface, In Bioengineering of the skin", pp.3~19 (1997), Boca Raton CRC Press
- Khang G, "Natural scaffold biomaterials for tissue regeneration", Tissue. E ng. Regen. Med, 1, pp.9~11 (2004)
- Jelvehgari, M, "Nokhodchi A. The microsponge delivery system of benzoyl peroxide: preparation, characterization and release studies", Int. J. Pharm, 308, pp.124~132 (2006)
- Jenquin MR, "Characterization of acrylic resin matrix films and mechanism of drug", polymer interaction, 1994, pp.101, 23~34
- Jamea JH, "The use of Op-site, a vapor permeable dressing on skin graft donor sites", J . Plast. Surg, 28, pp.107~108 (1975)
- Kang DY, "Swelling Kinetics and Release Characteristics of Crosslinked Chitosan", Chitin. Chitosan, 32, pp.1213~1223 (1994)
- Kanto TG, "Ketoprofen; A review of its pharmacological and clinical properties", Pharmacotherapy, 6, pp.93~103 (1986)
- Kawamura Y, "Adsorption of Metal Ions on Polyaminated Highly Porous Chitosan Chelating Resin", Ind. Eng. Chem. Res, 32, pp.386~391 (1993)
- Kawashima Y, "Role of the solvent-diffuse rate modifier in a new emulsion solvent diffusion method for preparation of ketoprofen microspheres, Microencapsulation", Pharmacotherapy, 10, pp.329~340 (1993)
- Kost J, "Responsive Polymer Systems for Controlled Delivery of Therapeutics", TIBTECH, 10, pp.127~131 (1992)
- Lee AH, "Chitosan, a natural regulator in plant-fungal pathogen interactions, increases for crop yields, In", pp.291~302 (1984), Aca. Press Inc
- Peng, T, "Structural Changes of pH-Sensitive Chitosan", Polyether Hydrogels in Different pH Solution, 1994, pp.32, 591~596
- Sundaram G, "Swelling of pH-sensitive Chitosan-poly (vinyl alcohol) Hydrogels", J. App. Poly. Sci, 102, pp.4665~4671 (2006)
