Comparison of Morphology and Color Change Based on Chitosan-PVA Hybrid Mask Sheets
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This study investigated the structure and properties of chitosan-PVA hybrid mask sheets prepared with 2% chitosan and 10% PVA. Using FT-IR, their intermolecular interactions in the mixture showed a ratio of 60% and 40%, respectively. To obtain a microporous structure, sodium bicarbonate and glutalaldehyde were applied to the mixture to give cross-linked chitosan-PVA hybrid mask sheets. Glutaraldehyde was used to adjust the strength of the hybrid mask sheets. Hunter L*, a*, and b* values were used for comparison of color differences between the chitosan-PVA hybrid mask sheet and the cross-linked chitosan-PVA mask sheet. A decrease in L* and increase in b* were observed with the increase in the ratio of chitosan to PVA. ΔE values were also increased by chitosan in a concentrationdependent manner. This means that the glutaraldehyde is expected to form the Schiff base upon nucleophilic reaction by the primary amine groups of the chitosan. The morphology of the cross-linked structure showed evenly well distributed micropores with an average size of 10 μm. This unique structure resulted in a large surface area that could hold a large amount of water. Lysozyme as a mucolytic enzyme dissolved the cross-linked chitosan-PVA hybrid mask sheet by hydrolyzing the glycosidic linkage of the chitosan backbone. These highly swellable and enzyme responsible hybrid mask sheets can enable the potential transfer of cosmetic active compounds.
Abstract
This study investigated the structure and properties of chitosan-PVA hybrid mask sheets prepared with 2% chitosan and 10% PVA. Using FT-IR, their intermolecular interactions in the mixture showed a ratio of 60% and 40%, respectively. To obtain a microporous structure, sodium bicarbonate and glutalaldehyde were applied to the mixture to give cross-linked chitosan-PVA hybrid mask sheets. Glutaraldehyde was used to adjust the strength of the hybrid mask sheets. Hunter L*, a*, and b* values were used for comparison of color differences between the chitosan-PVA hybrid mask sheet and the cross-linked chitosan-PVA mask sheet. A decrease in L* and increase in b* were observed with the increase in the ratio of chitosan to PVA. ΔE values were also increased by chitosan in a concentrationdependent manner. This means that the glutaraldehyde is expected to form the Schiff base upon nucleophilic reaction by the primary amine groups of the chitosan. The morphology of the cross-linked structure showed evenly well distributed micropores with an average size of 10 μm. This unique structure resulted in a large surface area that could hold a large amount of water. Lysozyme as a mucolytic enzyme dissolved the cross-linked chitosan-PVA hybrid mask sheet by hydrolyzing the glycosidic linkage of the chitosan backbone. These highly swellable and enzyme responsible hybrid mask sheets can enable the potential transfer of cosmetic active compounds.
참고문헌 (41)
- Abdolmaleki A, "Adsorption of tetracycline from water using glutaraldehyde crosslinked electrospun nanofibers of chitosan", poly (vinyl alcohol), 2018, pp.77, 1324~1335
- Ali N, "The effect of formulation type on the release of benzoyl peroxide from microsponges", Iran J Pharm Sci, 1, pp.131~142 (2005)
- Bahrami SB, "Poly (vinyl alcohol) chitosan blends, preparation, mechanical and physical properties", Iran Polym, 12, pp.139~146 (2003)
- Chandy T, "Prostaglandin E1-immobilized poly (vinyl alcohol) blended chitosan membranes: blood compatibility and permeability properties", J Appl Polym Sci, 44, pp.2145~2156 (1992)
- Chong TF, "Instrumental measurement and control of color", Rev Prog Coloration, 18, pp.47~55 (1988)
- Chuang WY, "Properties of te poly (vinyl alcohol)", chitosan blend and its effect on the culture of fibroblast in vitro, 1999, pp.20, 1479~1487
- Gatenholm P, "Biodegradable natural composite, processing and properties", J Appl Polym Sci, 45, pp.1667~1677 (1992)
- Gunasekaran S, "Swelling of pH-sensitive chitosan-poly (vinyl alcohol) hydrogels", J Appl Polym Sci, 102, pp.4665~4671 (2006)
- Gutha Y, "Antibacterial and wound healing properties of chitoan", poly (vinyl alcohol), Int J Biol Macromol, pp.2017, 103[DOI]
- Hasegawa M, "Characterization of cellulose-chitosan blend films", J Appl Polym Sci, 45, pp.1873~1879 (1992)
- Heller J, "Development of enzymatically degradable protective coatings for use in triggered drug delivery systems : derivatized starch hydrogels", Biomaterials, 11, pp.345~350 (1990)
- Hsieh WC, "Morphology and characterization of 3D micro-porous structured chitosan scaffolds for tissue engineering", Colloids Surf B Biointerfaces, 57, pp.250~255 (2007)
- Huang M, "Investigation of α-PVA", s-PVA hydrogels prepared by freeze thawing method, 2012, pp.13, 955~963
- Khodja AN, "Evaluation of healing activity of PVA", chitosan hydrogels on deep second degree burn : pharmacological and toxicological tests, 2013, pp.39, 98~104
- JH, "Properties and swelling characteristics of cross-linked poly (vinyl alcohol)", chitosan blend, 1992, pp.45, 1711~1717
- Kuma A, "Synthesis of physically cross-linked PVA", chitosan loaded silver nanoparticles hydrogels with tunable mechanical properties and antibacterial effects, 2020, pp.149, 1262~1274
- Li Q, "Heterogeneous N-deacetylation of chitin in alkaline solution", J Bioact Compat Polym, 7, pp.370~397 (1992)
- Lee YM, "Pervaporation of water-ethanol through poly (vinyl alcohol)", chitosan blend membrane, 1992, pp.29, 423~429
- Lee TW, "Hydrogel patches containing triclosan for acne treatment", Eur J Pharm Biopharm, 56, pp.407~412 (2003)
- Maeda R, "Enzymatic hydrolysis reaction of water-soluble chitin derivatives with egg white lysozyme", J Ferment Bioeng, 84, pp.478~479 (1997)
- Mahato KK, "Fabrication of polyvinyl alcohol", chitosan oligosaccharide hydrogel : physicochemical characterizations and in vitro drug release study, 2020, pp.25, 353~361
- Mansu HS, "FTIR spectroscopy characterization of poly (vinyl alcohol) hydrogel with different hydrolysis degree and chemically crosslinked with glutaraldehyde", Mater Sci Eng, 28, pp.539~548 (2008)
- Martin P, "Wound healing-aiming for perfect skin regeneration", Science, 276, pp.76~81 (1997)
- Mathew J, "Study of blood compatible polymer I. Modification of poly (vinyl alcohol)", Polym J, 24, pp.31~41 (1992)
- Ohya Y, "Release behavior of 5-fluorouracil from chitosan-gel microspheres immobilizing 5-fluorouracil derivative coated with polysaccharides and their cell specific recognition", J Microencapsulation, 10, pp.1~9 (1993)
- Olarte A, "Physico-chemical properties of a hybrid biomaterial (PVA", chitosan) reinforced with conductive fillers, 2021, pp.11, 3040~3041
- Paradossi G, "New hydrogels based on poly (vinyl alcohol)", J Polym Sci Polym Chem, 34, pp.3417~3496 (1996)
- Rahul N, "Response surface methodology for the optimization of chitosan microspheres", J Pharm Sci Res, 3, pp.1214~1220 (2011)
- Rieger MM, "Skin moisturizers II-the effects of cosmetic ingredient on human stratum corneum", J Soc Cosmet Chem, 25, pp.253~262 (1974)
- Stasko J, "Poly (vinyl alcohol) hydrogels", Proceed Estonian Acad Sci., 58, pp.63~66 (2009)
- Song Q, "Synthesis of cross-linking chitosan-PVA composite hydrogel and adsorption of Cu(II) ions", Water Sci Tech, 81, pp.1063~1070 (2020)
- Spencer TS, "Dry skin and skin moisturizers", Clin Dermatol, 6, pp.24~28 (1988)
- Swetha A, "Formulation and in vitro evaluation of etodolac entrapped in microsponge based drug delivery system", Int J Pharma, 1, pp.73~80 (2011)
- Tsai HS, "Properties of hydrophilic chitosan network membranes by introducing binary crosslink agents", Polym Bull, 60, pp.103~113 (2008)
- Tripathi S, "Physicochemical and bioactivity of cross-linked chitosan-PVA film for food packaging applications", Int J Biol Macromol, 45, pp.372~376 (2009)
- Venkataprasanna KS, "Fabrication of chitin", PVA, CuO patch for potential wound healing application, pp.Int J Biol Macromol, 2019[DOI]
- Viral S, "Microsponge drug delivery", Int J Res Pharm Sci, 1, pp.212~218 (2010)
- Wang G, "Preparation of CuS", polyvinyl alcohol-chitosan nanocomposites with photocatalysis activity and antibacterial behavior against G+, Int J Biol Macromol, pp.2020, 15[DOI]
- Wehr RF, "Considerations in selecting a moisturizer", Cutis, 39, pp.512~515 (1987)
- Wu MS, "Effect of a skin moisturizer on the water distribution in human stratum corneum", J Invest Dermatol, 81, pp.446~448 (1983)
- Yang W, "Polyvinyl alcohol", chitosan hydrogels with enhanced antioxidant and antibacterial properties induced by lignin nanoparticles, 2018, pp.181, 275~284