리보플라빈이 함유된 키토산 마스크팩의 제조 및 특성에 관한 연구
Studies on the Preparation of Chitosan Mask Pack Containing Riboflavin and There Characteristics
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This study was to investigate a preparation and characteristics of a peel-off type mask pack with chitosan, which is biocompatible biopolymer, as a model cosmetic delivery system. Chitosan microbeads having riboflavin for cosmetic delivery system have been obtained using capillary extrusion method. Intermolecular hydrogen bonding bands between ,chitosan molecule and riboflavin were observed at 3,429 cm^(-1) and 1,088 cm^(-1) in FT-IR spectrum. The band shifts may be assigned to a strong interaction due to intermolecular hydrogen bond between two molecules. The prototype formulation of peel-off type mask pack was also prepared by conventional method.The parameters to evaluate cosmetic effects consisted of skin hydration, pH, skin sebum, erythema index, TEWL, L*a*b* values. It was concluded that chitosan microbeads containing of riboflavin considered as a good candidate for the preparation of a functional peel-off type mask pack. The releasing property of riboflavin from chitosan microbeads is not clearly studied and requires further investigation.
Abstract
This study was to investigate a preparation and characteristics of a peel-off type mask pack with chitosan, which is biocompatible biopolymer, as a model cosmetic delivery system. Chitosan microbeads having riboflavin for cosmetic delivery system have been obtained using capillary extrusion method. Intermolecular hydrogen bonding bands between ,chitosan molecule and riboflavin were observed at 3,429 cm^(-1) and 1,088 cm^(-1) in FT-IR spectrum. The band shifts may be assigned to a strong interaction due to intermolecular hydrogen bond between two molecules. The prototype formulation of peel-off type mask pack was also prepared by conventional method.The parameters to evaluate cosmetic effects consisted of skin hydration, pH, skin sebum, erythema index, TEWL, L*a*b* values. It was concluded that chitosan microbeads containing of riboflavin considered as a good candidate for the preparation of a functional peel-off type mask pack. The releasing property of riboflavin from chitosan microbeads is not clearly studied and requires further investigation.
참고문헌 (13)
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