Morphological, Physical Characterization of Poly(acrylic acid) Nanogel Prepared by Electron Beam Irradiation
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Nanogels are internally cross-linked particles of sub-micrometer size made of hydrophilicpolymers and are considered a distinct type of macromolecules, compared with linear andbranched polymers or macroscopic gels. In this study, we studied a method of radiation inducedsynthesis of nanogels, which allows us to obtain tailored intra-molecularly crosslinked macromoleculesof independently chosen molecular weight and dimensions. Thus, we report the possibilityof applying the prepared nanogels using poly(acrylic acid) through electron beam irradiationfor potential application as biomaterials. The nanogels were characterized by scanningelectron microscopy (SEM). In addition, the size and zeta-potential of nanogels were measured bya particle size analyzer (PSA). The nanogels were prepared at an approximate size of 180 nm at100 kGy and were spherical in shapes. The size of the nanogels decreased with increasing irradiationdoses, and the absolute value of zeta potential increased with increasing irradiation doses.
Abstract
Nanogels are internally cross-linked particles of sub-micrometer size made of hydrophilicpolymers and are considered a distinct type of macromolecules, compared with linear andbranched polymers or macroscopic gels. In this study, we studied a method of radiation inducedsynthesis of nanogels, which allows us to obtain tailored intra-molecularly crosslinked macromoleculesof independently chosen molecular weight and dimensions. Thus, we report the possibilityof applying the prepared nanogels using poly(acrylic acid) through electron beam irradiationfor potential application as biomaterials. The nanogels were characterized by scanningelectron microscopy (SEM). In addition, the size and zeta-potential of nanogels were measured bya particle size analyzer (PSA). The nanogels were prepared at an approximate size of 180 nm at100 kGy and were spherical in shapes. The size of the nanogels decreased with increasing irradiationdoses, and the absolute value of zeta potential increased with increasing irradiation doses.
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