화장료 소재로서 뜰보리수 과실 추출물의 항산화, 항염증 및 항노화 활성
Antioxidant, Anti-inflammatory and Anti-aging Activities of Elaeagnus multiflora Fruit Extracts as a Cosmetic Material
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Elaeagnus multiflora, commonly called cherry silver berry, is used as a medicinal material in China and Korea. The purpose of this study was to investigate the antioxidant and anti-aging properties of the fruit extract of E. multiflora using different solvents, such as hot water extract (HWE), butylene glycol with water and ethanol extract (BGE), and propylene glycol with water and ethanol extract (PGE). In the measurement of the radical scavenging of 2,2’-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 2,2-diphenyl-1-picryl hydrazyl (DPPH), PGE showed the highest scavenging rates of 84.27% and 95.30%, respectively at a concentration of 2 mg/mL. The SOD-like activity was the highest, 39.98%, in HWE at 2.0 mg/mL, xanthine oxidase inhibition showed 44.98% in HWE. In the analysis of anti-aging effect at 2.0 mg/mL, collagenase and elastase showed the highest inhibition activities, viz. 37.83% and 19.78% in HWE, respectively. In the astringent effect analysis, HWE showed about 90% activity at a concentration of 5.0 mg/mL and about 50% at 25 mg/mL. Tyrosinase inhibition activity for whitening effect was the highest (44.24%) in PGE, followed by HWE, 40.07% at 2.0 mg/mL. Results revealed that PGE had excellent antioxidant activity and HWE showed better anti-inflammatory, anti-aging and astringent effects than BGE and PGE. Therefore, E. multiflora fruits seems to be a natural resource that can be used as a cosmetic material.
Abstract
Elaeagnus multiflora, commonly called cherry silver berry, is used as a medicinal material in China and Korea. The purpose of this study was to investigate the antioxidant and anti-aging properties of the fruit extract of E. multiflora using different solvents, such as hot water extract (HWE), butylene glycol with water and ethanol extract (BGE), and propylene glycol with water and ethanol extract (PGE). In the measurement of the radical scavenging of 2,2’-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 2,2-diphenyl-1-picryl hydrazyl (DPPH), PGE showed the highest scavenging rates of 84.27% and 95.30%, respectively at a concentration of 2 mg/mL. The SOD-like activity was the highest, 39.98%, in HWE at 2.0 mg/mL, xanthine oxidase inhibition showed 44.98% in HWE. In the analysis of anti-aging effect at 2.0 mg/mL, collagenase and elastase showed the highest inhibition activities, viz. 37.83% and 19.78% in HWE, respectively. In the astringent effect analysis, HWE showed about 90% activity at a concentration of 5.0 mg/mL and about 50% at 25 mg/mL. Tyrosinase inhibition activity for whitening effect was the highest (44.24%) in PGE, followed by HWE, 40.07% at 2.0 mg/mL. Results revealed that PGE had excellent antioxidant activity and HWE showed better anti-inflammatory, anti-aging and astringent effects than BGE and PGE. Therefore, E. multiflora fruits seems to be a natural resource that can be used as a cosmetic material.
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