맥문동(Liriope platyphylla) 열매 추출물의 항노화 효과 및 항산화 활성
Anti-aging and Antioxidant Activities of Extracts from Liriope platyphylla Fruits
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Anti-aging and antioxidant activity of extracts from Liriope platyphylla fruits were investigated for availability of cosmetics and beauty industrial materials. The flavonoid and polyphenol compounds of water-soluble extract(WE) were 51.02 mg/g and 163.52 mg/g, those of methanolic extract(ME) were 87.02 mg/g and 92.30 mg/g, respectively. The tyrosinase inhibition rate for a whitening effect was 17.12% in the ME at 1,000 μg/mL. In the analysis of collagenase inhibitory activity, ME showed definitely superior effect to ascorbic acid at all experimental concentrations except in the result of 1,000 μg/mL condition. In the results of elastase inhibition, the activity was increased with an increment of concentration and WE showed the highest activity of 43.23% at 1,000 μg/mL, additionally WE had higher effects than that of ME in all concentrations. In measurements of xanthine oxidase inhibitory activity, WE and ME showed a significantly high inhibition activity of 94.70% and 95.65%, respectively, at 1,000 μg/mL and the activity was increased in proportional to the concentration. The SOD-like activity was the highest as 41.85% in the measurement of ME at 1,000 μg/mL. Electron donating abilities of WE and ME were over 60%, and then ME had excellent effect compare to ascorbic acid. In the analysis of nitrite scavenging ability, WE(97.93%) and ME(96.03%) showed a significantly higher effect at pH 1.2 condition. These results suggest that the extract of L. platyphylla fruits have the potential to be used as whitening, anti-wrinkling agent and antioxidant resources.
Abstract
Anti-aging and antioxidant activity of extracts from Liriope platyphylla fruits were investigated for availability of cosmetics and beauty industrial materials. The flavonoid and polyphenol compounds of water-soluble extract(WE) were 51.02 mg/g and 163.52 mg/g, those of methanolic extract(ME) were 87.02 mg/g and 92.30 mg/g, respectively. The tyrosinase inhibition rate for a whitening effect was 17.12% in the ME at 1,000 μg/mL. In the analysis of collagenase inhibitory activity, ME showed definitely superior effect to ascorbic acid at all experimental concentrations except in the result of 1,000 μg/mL condition. In the results of elastase inhibition, the activity was increased with an increment of concentration and WE showed the highest activity of 43.23% at 1,000 μg/mL, additionally WE had higher effects than that of ME in all concentrations. In measurements of xanthine oxidase inhibitory activity, WE and ME showed a significantly high inhibition activity of 94.70% and 95.65%, respectively, at 1,000 μg/mL and the activity was increased in proportional to the concentration. The SOD-like activity was the highest as 41.85% in the measurement of ME at 1,000 μg/mL. Electron donating abilities of WE and ME were over 60%, and then ME had excellent effect compare to ascorbic acid. In the analysis of nitrite scavenging ability, WE(97.93%) and ME(96.03%) showed a significantly higher effect at pH 1.2 condition. These results suggest that the extract of L. platyphylla fruits have the potential to be used as whitening, anti-wrinkling agent and antioxidant resources.
참고문헌 (54)
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