복분자 추출물의 나노입자화를 통한 항산화 및 미백 효과 증진
Antioxidant Activities and Skin-Whitening Effects of Nano-encapsuled Water Extract from Rubus coreanus Miquel
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Abstract
This study was performed to improve antioxidant activities and skin-whitening effects of Rubus coreanus Miquel extracts by nano-encapsulation. R. coreanus was extracted at 60℃ and encapsulated by lecithin and gelagine. Nanoencapsulated extracts showed highest free radical scavengering effect as 97.62% in adding sample (500 ㎍/㎖), compared to the extracts from conventional processes. It was showed strong inhibition effect on melanin production test by Clone M-3 cells as 55.23%. High inhibitory potency on tyrosinase was also measured as 155.8% by adding nano-sample of 1 ㎎/㎖. The improvement of biological activity was demonstrated by real time confocal microscope. We could consider that the water soluble extracts of R. coreanus could be definitely enhanced by nano-encapsulated as a potent natural resources for antioxidant and skin-whitening agent.
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