본문 바로가기
KERD
논문KCI 등재

아동용 운동놀이기구를 이용한 일회성 운동 시 산소소비량 및 성장관련 호르몬의 반응

Responses of Oxygen Consumption and Hormones Related Growth to Acute Exercise Using Sporting Equipment

김용진|김광회|김순기|박동호
국민체육진흥공단 한국스포츠과학원 (Korea Institute of Sport Science)|2009.12|체육과학연구 (Korean Journal of Sport Science)|제20권 제4호|pp. 720-733|DOI 10.24985/kjss.2009.20.4.720

0

조회

0

다운로드

1

인용

0

참고문헌

키워드

아동child운동exercise성장성장호르몬IGF-1키GH운동놀이기구IGFBP-3linear growthToyatti
주제분류체육

초록

이 연구는 10명의 아동(4∼5세)를 대상으로 아동용 운동놀이기구(토이아띠)를 이용하여 20분동안 운동 때 소모되는 순수한 산소소비량(VO2ml/kg/min)을 산출함으로써 운동 때 소모되는 칼로리소비량(kcal/kg/min)과 운동 전·후 GH(growth hormone), IGF-1(insulin-like growth factor-1), cortisol, thyroxine(T4), insulin 및 IGFBP-3(Insulin-like growth factor binding protein-3)와 같은 성장관련 호르몬의 변화량에 대한 기초자료를 제공하는데 목적이 있었으며, 그 결과는 다음과 같다. 1. 20분간 놀이기구를 타고 운동할 때의 평균 분당심박수는 174.12±16.52 bpm에 해당하며, 운동강도는 VO2max의 67.33±10.92% 또는 HRmax의 80.87±7.75%에 해당하였다. 이때의 분당칼로리 소비량은 0.1774kcal/kg/min이었다. 2. 아동용 놀이기구를 이용하여 약 67.33±10.92% VO2max의 운동강도로 20분 동안 운동한 후 GH는 378.37%(6.01±2.97 vs 22.74±4.59 ng/ml, p=.008) 그리고 IGF-1은 108.46%(152.44±9.55 vs 165.33±11.76 ng/ml, p=.036) 각각 유의하게 증가한 반면 insulin은 54.52%(14.27±2.34 vs 7.78±2.06 ㎍/dl, p=.016) 감소하였다. 그러나 cortisol, T4, IGFBP-3 및 IGF-1/IGFBP-3의 비율은 유의한 변화를 나타내지 않았다. 3. 운동전·후 일부 관찰변인간의 상관관계에서는, 나이가 증가할수록 몸무게(p= .032)와 체지방률(p= .005)이 유의하게 증가하는데 반하여 키의 성장은 나이와는 유의한 상관관계(p=.077)를 보이지 않았으나 골연령과는 유의한 정상관(p= .043)을 나타내었다. 또한, 호르몬의 경우 안정시 insulin은 안정시 및 운동 후 IGF-1의 농도와 각각 매우 높은 정상관(p=.021, p=.001)을 보였다. 또한, GH는 운동중 VO2가 높을수록 농도가 높아지는 정상관(r= .674, p= .047)을 보인 반면 IGF-1은 운동 중 평균심박수(HR)와는 역상관(r= -.734, p= .024)을 보였다. 이상의 결과를 종합하여 볼 때, 아동용 놀이기구를 이용하여 53∼84% VO2max의 강도로 20분 동안의 운동 시 GH와 IGF-1의 증가 및 isulin의 감소를 유발할 수 있다. 그리고 GH의 농도는 운동강도와 비례하여 증가하는 반면 IGF-1의 운동반응은 혈청 insulin의 농도에 직접적으로 의존하는 것을 알수 있었다.

Abstract

The purpose of this study was to examine the response of oxygen consumption (VO2 ml/kg/min) and hormones related growth to acute exercise using Toyatti in child(six boys and four girls). Ten 4 to 5 years (60.60±6.70 months) old child exercised 20 min using Toyatti at the level of 53∼84% VO2max. We measured VO2 (ml/kg/min) during the exercise to calculate energy expenditure (kcal/kg/min) during exercise. Venous blood samples were obtained before, 5min after exercise for the measurement of serum GH (growth hormone), IGF-1 (insulin-like growth factor-1), cortisol (COR), thyroxine (T4), insulin (INS), and IGFBP-3 (Insulin-like growth factor binding protein-3). As results, average heart rates (HRs), %VO2max, %HRmax, and energy expenditure during 20min exercise using Toyatti were 174.12±16.52 bpm, 67.33±10.92%, 80.87%, and 0.1774 kcal/kg/min respectively. Seconds, Acute exercise did not affect significantly serum IGFBP-3, IGF-1/IGFBP-3 ratio, COR and T4 but GH (↑378.37%, 6.01±2.97 vs 22.74±4.59 ng/ml, p=.008) and IGF-1 (↑108.46%, 152.44±9.55 vs 165.33±11.76 ng/ml, p=.036) were significantly increased after exercise. Third, the age was positively correlated with body weight(r= 0.674, p= .032), % body fat (r= 0.808, p= .005), whereas the growth in height was not significantly correlated with the age (r= 0.582, p= .077) but the bone age (r= 0.648, p= .043). In addition, the basal and post-exercise IGF-1 levels were positively correlated with the basal insulin concentrations (r= .746, p= .021; r= .906, p= .001, respectively). In additioin, average VO2 ml/kg/min during exercise was positively correlated with GH concentration (r= 0.674, p= .047), whereas IGF-1 concentration was negatively correlated with average HR (r= -0.734, p= .024), respectively. In conclusion, 20min exercise at the level of 53 to 84% VO2max using Toyatti might significantly increase in the concentration of GH and IGF-1, and significantly decrease in insulin concentration.

참고문헌 (69)

  1. 2007 세계인구현황보고서 한국어판. 도시성장과 잠재력(Unleashing the Potential of Urban Growth), , 인구보건복지협회, 유엔인구기금, 보건복지부, 1~77 (2007)
  2. 박동호, "규칙적인 운동참여와 형태가 신장 성장, 신체구성 및 2차 성징에 미치는 영향", 체육과학연구, 14(3), pp.11~25 (2003), 국민체육진흥공단 체육과학연구원
  3. 청소년기의 운동이 신장성장에 미치는 영향, "박동호", 국민체육진흥공단 체육과학연구원, 1~82 (2002)
  4. 비만해법 운동이 최선이다, "성봉주", 국민체육진흥공단 체육과학연구원, 1~203 (2002)
  5. 한국의 체육지표, "신승윤", 한국체육과학연구원, 1~312 (1995)
  6. 한국의 체육지표, "유의동", 국민체육진흥공단 체육과학연구원, 1~368 (2007)
  7. ACSM, "ACSM's Guidelines for exercise testing and prescription (5th ed.)" (1995), Lippingcott Williams., & Wilkins
  8. Adiyaman, P., "Alterations in serum growth hormone (GH)", GH dependent ternary complex components (IGF-I, IGFBP-3, ALS, IGF-I, J Pediatr Endocrinol Metab., pp.2004, 17(6)[DOI]
  9. Albertsson-Wikland, K., "Analysis of 24-hour growth hormone profiles in healthy boys and girls of normal stature: relation to puberty", J. Clin. Endocrinol. Metab., 78(5), pp.1195~1201 (1994)
  10. Attanasio, A. F., "Continued growth hormone (GH) treatment after final height is necessary to complete somatic development in childhood-onset GH-deficient patients", J. Clin. Endocrinol. Metab., 89(10), pp.4857~4862 (2004)
  11. Beauville, M., "Effect of long-term rhGH administration in GH-deficient adults on fat cell epinephrine response", Am. J. Physiol., 263(3), pp.E467~E472 (1992)
  12. Berg, U., "Exercise and circulating insulin-like growth factor I", Horm Res., 62(1), pp.50~58 (2004)
  13. Biro, F. M., "Impact of timing of pubertal maturation on growth in black and white female adolescents: The National Heart, Lung, and Blood Institute Growth and Health Study", J. Pediatr., 138(5), pp.636~643 (2001)
  14. Brahm, H., "Net fluxes over working thigh of hormones, growth factors and biomarkers of bone metabolism during short lasting dynamic exercise", Calcif. Tissue Int., 60(2), pp.175~180 (1997)
  15. Cappon, J., "Effect of brief exercise on circulating insulin-like growth factor I", J. Appl. Physiol., 76(6), pp.2490~2496 (1994)
  16. Chrousos, G. P., "Regulation and dysregulation of the hypothalamic-pituitary-adrenal axis. The corticotropinreleasing hormone perspective", Endocrinol. Metab. Clin. North. Am., 21(4), pp.833~858 (1992)
  17. Clemmons, D. R., "Value of insulin-like growth factor system markers in the assessment of growth hormone status", Endocrinol. Metab. Clin. North. Am., 36(1), pp.109~129 (2007)
  18. Deligiannis, A., "Plasma TSH, T3, T4 and cortisol responses to swimming at varying water temperatures", Br. J. Sports Med., 27(4), pp.247~250 (1993)
  19. Di Luigi, L., "Growth hormone and insulin-like growth factor I responses to moderate submaximal acute physical exercise in man: effects of octreotide, a somatostatin analogue, administration", Int. J. Sports Med., 18(4), pp.257~263 (1997)
  20. Dumitrescu, A. M., "A Novel Syndrome Combining Thyroid and Neurological Abnormalities Is Associated with Mutations in a Monocarboxylate Transporter Gene", Am. J. Hum. Genet., 74(1), pp.168~175 (2004)
  21. Eliakim, A., "Reduced exercise-associated response of the GH-IGF-I axis and catecholamines in obese children and adolescents", J. Appl. Physiol., 100(5), pp.1630~1637 (2006)
  22. Felsing, N. E., "Effect of low and high intensity exercise on circulating growth hormone in men", J. Clin. Endocrinol. Metab., 75(1), pp.157~162 (1992)
  23. Frisch, R. E., "Body fat, menarche, fitness and fertility", Hum Reprod., 2(6), pp.521~533 (1987)
  24. Galbo, H., "Catecholamines and pancreatic hormones during autonomic blockade in exercising man", Acta Physiol. Scand., 101(4), pp.428~437 (1977)
  25. Garn, S. M., "Maturational timing as a factor in female fatness and obesity", Am. J. Clin. Nutr., 43(6), pp.879~883 (1986)
  26. Giustina, A., "Pathophysiology of the neuroregulation of growth hormone secretion in experimental animals and the human", Endocr. Rev., 19, pp.717~797 (1998)
  27. Guyton, A. C., "Textbook of Medical Physiology: Overview of the circulation (9th ed)" (1996), Saunders
  28. Hanaire-Broutin, H., "Effect of intraperitoneal insulin delivery on growth hormone binding protein, insulin-like growth factor (IGF)-I, and IGF-binding protein-3 in IDDM", Diabetologia, 39(12), pp.1498~1504 (1996)
  29. He, Q., "BMI in childhood and its association with height gain, timing of puberty, and final height", Pediatr. Res., 49(2), pp.244~251 (2001)
  30. Henriksen, E. J., "Invited review: Effects of acute exercise and exercise training on insulin resistance", J. Appl. Physiol., 93(2), pp.788~796 (2002)
  31. Hopkins, N. J., "Changes in circulating insulin-like growth factor-binding protein-1 (IGFBP-1) during prolonged exercise: effect of carbohydrate feeding", J. Clin. Endocrinol. Metab., 79(6), pp.1887~1890 (1994)
  32. Hulanicka, B., "Relationship between early puberty and the risk of hypertension", overweight at age 50: evidence for a modified Barker hypothesis among Polish youth, 2007, pp.5(1), 48~60
  33. Johannsson, G., "Two years of growth hormone (GH) treatment increase isometric and isokinetic muscle strength in GH-deficient adults", J. Clin. Endocrinol. Metab., 82(9), pp.2877~2884 (1997)
  34. Johannsson, G., "Growth hormone treatment of abdominally obese men reduces abdominal fat mass, improves glucose and lipoprotein metabolism, and reduces diastolic blood pressure", J. Clin. Endocrinol. Metab., 82(3), pp.727~734 (1997)
  35. Kamel, A., "Effects of growth hormone treatment in obese prepubertal boys", J. Clin. Endocrinol. Metab., 85(4), pp.1412~1419 (2000)
  36. Kanaley, J. A., "Obesity attenuates the growth hormone response to exercise", J. Clin. Endocrinol. Metab., 84(9), pp.3156~3161 (1999)
  37. Kaprio, J., "Common genetic influences on BMI and age at menarche", Hum. Biol., 67(5), pp.739~753 (1995)
  38. Kaytor, E. N., "Insulin-responsive nuclear proteins facilitate Sp1 interactions with the insulin-like growth factor-I gene", J. Biol Chem., 276(40), pp.6896~6901 (2001)
  39. Kemper, H. C., "Rate of maturation during the teenage years: nutrient intake and physical activity between ages 12 and 22", Int. J. Sport Nutr., 7, pp.229~240 (1997)
  40. Koistinen, H., "Effect of marathon run on serum IGF-I and IGF-binding protein 1 and 3 levels", J. Appl. Physiol., 80(3), pp.760~764 (1996)
  41. Kraemer, W. J., "Hormonal responses and adaptations to resistance exercise and training", Sports Med., 35(4), pp.339~361 (2005)
  42. Lanzi, R., "Time course and mechanism of growth hormone's negative feedback effect on its own spontaneous release", Endocrinology, 130(2), pp.780~788 (1992)
  43. Lei, J., "Thyroid hormone stimulates Na-K-ATPase activity and its plasma membrane insertion in rat alveolar epithelial cells", Am. J. Physiol. Lung. Cell. Mol. Physiol., 285(3), pp.L762~L772 (2003)
  44. LeRoith, D., "The insulin-like growth factor family of peptides, binding proteins and receptors: their potential role in tissue regeneration", Adv. Exp. Med. Biol., 321, pp.21~28 (1992)
  45. Mauras, N., "Augmentation of growth hormone secretion during puberty: evidence for a pulse amplitude-modulated phenomenon", J. Clin. Endocrinol. Metab., 64(3), pp.596~601 (1987)
  46. Näveri, H., "Metabolic and hormonal changes in moderate and intense long-term running exercises", Int. J. Sports. Med., 6(5), pp.276~281 (1985)
  47. Nemet, D., "Effect of intense exercise on inflammatory cytokines and growth mediators in adolescent boys", Pediatrics, 110(4), pp.681~689 (2002)
  48. Nindl, B. C., "Overnight responses of the circulating IGF-I system after acute, heavy-resistance exercise", J. Appl. Physiol., 90(4), pp.1319~1326 (2001)
  49. O'Connell, M., "Changes in serum concentrations of 3,3',5'-triiodothyronine and 3,5,3'-triiodothyronine during prolonged moderate exercise", J. Clin. Endocrinol. Metab., 49(2), pp.242~246 (1979)
  50. Petridou, E., "Determinants of age at menarche as early life predictors of breast cancer risk", Int. J. Cancer, 68(2), pp.193~198 (1996)
  51. Pomerants, T., "Impact of acute exercise on bone turnover and growth hormone", insulin-like growth factor axis in boys, 2008, pp.48(2), 266~271
  52. Post, G. B., "Nutrient intake and biological maturation during adolescence. The Amsterdam growth and health longitudinal study", Eur. J. Clin. Nutr., 47(6), pp.400~408 (1993)
  53. Pritzlaff, C. J., "Catecholimine release, growth hormone secretion, and energy expenditure during exercise vs. recovery in men", J. Appl. physiol., 89, pp.937~946 (2000)
  54. Pritzlaff, C. J., "Impact of acute exercise intensity on pulsatile growth hormone release in men", J. Appl. Physiol., 87(2), pp.498~504 (1999)
  55. Raastad, T., "Hormonal responses to high- and moderate-intensity strength exercise", Eur J Appl Physiol., 82(1), pp.121~128 (2000)
  56. Rahkila, P., "Beta-endorphin and corticotropin release is dependent on a threshold intensity of running exercise in male endurance athletes", Life Sci., 43(6), pp.551~558 (1988)
  57. Russell-Jones, D. L., "The effect of growth hormone replacement on serum lipids, lipoproteins, apolipoproteins and cholesterol precursors in adult growth hormone deficient patients", Clin. Endocrinol (Oxf), 41(3), pp.345~350 (1994)
  58. Schwarz, A. J., "Acute effect of brief low- and high-intensity exercise on circulating insulin-like growth factor (IGF) I, II, and IGF-binding protein-3 and its proteolysis in young healthy men", J. Clin. Endocrinol. Metab., 81(10), pp.3492~3497 (1996)
  59. Serdula, M. K., "Do obese children become obese adults? A review of the literature", Prev. Med., 22(2), pp.167~177 (1993)
  60. Stunkard, A. J., "Behavior modification in the treatment of obesity. The problem of maintaining weight loss", Arch. Gen. Psychiatry, 36(7), pp.801~806 (1979)
  61. Treloar, S. A., "Age at menarche as a fitness trait: nonadditive genetic variance detected in a large twin sample", Am. J. Hum. Genet., 47(1), pp.137~148 (1990)
  62. Turcotte, L. P., "Skeletal muscle insulin resistance: roles of fatty acid metabolism and exercise", Phys. Ther., 88(11), pp.1279~1296 (2008)
  63. Ubertini, G., "Young elite athletes of different sport disciplines present with an increase in pulsatile secretion of growth hormone compared with non-elite athletes and sedentary subjects", J. Endocrinol. Invest., 31(2), pp.138~145 (2008)
  64. Vahl, N., "Abdominal adiposity rather than age and sex predicts mass and regularity of GH secretion in healthy adults", Am. J. Physiol., 272, pp.E1108~E1116 (1997)
  65. van Lenthe, F. J., "Rapid maturation in adolescence results in greater obesity in adulthood: the Amsterdam Growth and Health Study", Am. J. Clin. Nutr., 64(1), pp.18~24 (1996)
  66. Weltman, A., "Endurance training amplifies the pulsatile release of growth hormone: effects of training intensity", J. Appl. Physiol., 72(6), pp.2188~2196 (1992)
  67. Westermark, K., "Growth factors and the thyroid: effects of treatment for hyper-and hypothyroidism on serum IGF-I and urinary epidermal growth factor concentrations", Acta Endocrinol (Copenh), 118(3), pp.415~421 (1988)
  68. Wuster, C., "Growth hormone and bone metabolism", Acta Endocrinol (Copenh), 128(2), pp.14~18 (1993)
  69. Yakar, S., "Circulating levels of IGF-1 directly regulate bone growth and density", J. Clin. Invest., 110(6), pp.771~781 (2002)

관련 논문AI추천

비만아동의 태권도 수련이 hs-CRP, Growth hormone, Insulin-like growth factor-1에 미치는 영향김문희국민체육진흥공단 한국스포츠과학원 · 체육과학연구2005 · 제16권 제2호태권도 수련이 사춘기 이전 아동의 혈중지질 및 성장관련인자에 미치는 영향김인애, 양윤권국기원 · 국기원 태권도연구2017 · 제8권 제2호12주간 걷기와 놀이운동이 초등학교 비만여학생의 대사증후군위험인자와 성장호르몬에 미치는 영향백운효, 이경렬대한체육학회 · 대한체육학회지2022 · 제20권 제1호12주간 연속 및 비연속 순환운동이 남중학생의 호르몬 변화에 미치는 영향김진홍, 오수용, 최문기대한운동학회 · 아시아 운동학 학술지2014 · 제16권 제1호비만 청소년의 태권체조 프로그램 참여가 신체구성, 혈중지질 및 GH→IGF-I axis 수준에 미치는 영향김종식, 박수양, 조홍관대한무도학회 · 대한무도학회지2011 · 제13권 제2호장기간 태권도 수련이 초등학생의 신체구성, 건강체력과 성장인자에 미치는 영향이계행, 최공집대한무도학회 · 대한무도학회지2014 · 제16권 제2호

이 간행물의 다른 논문 (17건)

저항운동이 폐경 전·후 비만여성의 신체구성, 골밀도 및 아디포사이토카인에 미치는 영향신윤아, 정동춘, 임강일, 석민화pp. 693-703국내 남자 프로농구 승패 예측 모형 비교 연구구승환, 장성용, 김현수pp. 704-711태권도 선수의 4주간의 운동 훈련 중에 상기도 감염증의 이환과 타액 분비형 면역 글로불린 A의 변화와의 관련성이호성pp. 712-719엘리트 선수들의 한약섭취 실태와 도핑안정성 검증조현철, 김종규, 강성기, 천윤석pp. 734-742고온 환경에서의 트레드밀 운동이 흰쥐 뇌에서 세로토닌 발현, 신경세포 생성, 그리고 단기 기억력에 미치는 영향신말순, 서진희, 김창주, 임백빈, 이광식pp. 743-754
원문 보기