본문 바로가기
KERD
논문KCI 등재

Role of vitamin D and calcium in the relief of primary dysmenorrhea: a systematic review

Fatemeh Alsadat Rahnemaei|Fatemeh Abdi|Marjan Akhavan Amjadi|Farzaneh Zaheri
대한산부인과학회 (Korean Soceity of Obstetrics and Gynecology)|2021.01|Obstetrics & Gynecology Science|제64권 제1호|pp. 13-26|DOI doi.org/10.5468/ogs.20205

2

조회

0

다운로드

3

인용

0

참고문헌

키워드

Vitamin DCalciumPrimary dysmenorrhea
주제분류산부인과학

초록

Dysmenorrhea is one of the well-established problems among women of reproductive age and can have adverseeffects on the quality of life of the individual. Some studies suggest a relationship between vitamin D (Vit D) andcalcium deficiency and the emergence of early dysmenorrhea. Accordingly, a systematic study was performed toinvestigate the role of calcium and Vit D in the relief of primary dysmenorrhea. A systematic literature search wasperformed in PubMed, Web of Science, Scopus, Science Direct, and Google Scholar for papers published between2010 and 2020. The Consolidated Standards of Reporting Trials and Strengthening the Reporting of ObservationalStudies in Epidemiology checklists were used to assess the quality of the studies. The risk of bias was assessed usingthe Cochrane risk-of-bias assessment tool. Low calcium levels lead to an increase in uterine muscle contraction and cancause pain after decreased uterine blood flow. Furthermore, low levels of Vit D can increase primary dysmenorrhea byincreasing prostaglandin production or reducing intestinal calcium absorption. That being the case, Vit D and calciumintake can be effective in reducing the severity of primary dysmenorrhea and in reducing the rate of analgesic use. Low levels of Vit D and calcium are inversely related to the severity of primary dysmenorrhea, and Vit D and calciumintake can reduce the severity of primary dysmenorrhea and its associated systemic symptoms. Therefore, the use ofcalcium and Vit D supplements can be recommended to relieve dysmenorrhea.

Abstract

Dysmenorrhea is one of the well-established problems among women of reproductive age and can have adverseeffects on the quality of life of the individual. Some studies suggest a relationship between vitamin D (Vit D) andcalcium deficiency and the emergence of early dysmenorrhea. Accordingly, a systematic study was performed toinvestigate the role of calcium and Vit D in the relief of primary dysmenorrhea. A systematic literature search wasperformed in PubMed, Web of Science, Scopus, Science Direct, and Google Scholar for papers published between2010 and 2020. The Consolidated Standards of Reporting Trials and Strengthening the Reporting of ObservationalStudies in Epidemiology checklists were used to assess the quality of the studies. The risk of bias was assessed usingthe Cochrane risk-of-bias assessment tool. Low calcium levels lead to an increase in uterine muscle contraction and cancause pain after decreased uterine blood flow. Furthermore, low levels of Vit D can increase primary dysmenorrhea byincreasing prostaglandin production or reducing intestinal calcium absorption. That being the case, Vit D and calciumintake can be effective in reducing the severity of primary dysmenorrhea and in reducing the rate of analgesic use. Low levels of Vit D and calcium are inversely related to the severity of primary dysmenorrhea, and Vit D and calciumintake can reduce the severity of primary dysmenorrhea and its associated systemic symptoms. Therefore, the use ofcalcium and Vit D supplements can be recommended to relieve dysmenorrhea.

참고문헌 (58)

  1. Bajalan Z, "Nutrition as a potential factor of primary dysmenorrhea : a systematic review of observational studies", Gynecol Obstet Invest, 84, pp.209~224 (2019)
  2. Moini A, "The effect of vitamin D on primary dysmenorrhea with vitamin D deficiency : a randomized double-blind controlled clinical trial", Gynecol Endocrinol, 32, pp.502~505 (2016)
  3. Firouzi M, "Comparing the pattern of primary dysmenorrhea before and after childbirth", J Midwifery Reprod Health, 7, pp.1514~1521 (2019)
  4. Azagew AW, "Prevalence of primary dysmenorrhea, its intensity, impact and associated factors among female students' at Gondar town preparatory school, Northwest Ethiopia", BMC Womens Health, 20, pp.5~ (2020)
  5. Monday I, "Prevalence and correlation between diet and dysmenorrhea among high school and college students in Saint Vincent and Grenadines", Open Access Maced J Med Sci, 7, pp.920~924 (2019)
  6. Chen L, "Primary dysmenorrhea and self-care strategies among Chinese college girls: a cross-sectional study", BMJ Open, 9, pp.e026813~ (2019)
  7. Vlachou E, "Prevalence, wellbeing, and symptoms of dysmenorrhea among university nursing students in Greece", Diseases, 7, pp.1~14 (2019)
  8. Femi-Agboola DM, "Dysmenorrhea and its effects on school absenteeism and school activities among adolescents in selected secondary schools in Ibadan, Nigeria", Niger Med J, 58, pp.143~148 (2017)
  9. Acheampong K, "Prevalence and predictors of dysmenorrhea, its effect, and coping mechanisms among adolescents in Shai Osudoku District, Ghana", Obstet Gynecol Int, 2019, pp.5834159~ (2019)
  10. Kazama M, "Prevalence of dysmenorrhea and its correlating lifestyle factors in Japanese female junior high school students", Tohoku J Exp Med, 236, pp.107~113 (2015)
  11. Al-Matouq S, "Dysmenorrhea among highschool students and its associated factors in Kuwait", BMC Pediatr, 19, pp.80~ (2019)
  12. Sidi I, "Primary dysmenorrhea in the schools of Parakou: prevalence, impact and therapeutic approach", Gynecol Obstet(Sunnyvale), 6, pp.376~ (2016)
  13. Aktaş D, "Prevalence and factors affecting dysmenorrhea in female university students : effect on general comfort level", Pain Manag Nurs, 16, pp.534~543 (2015)
  14. Arafa AE, "Prevalence and patterns of dysmenorrhea and premenstrual syndrome among Egyptian girls(12–25 years)", Middle East Fertil Soc J, 23, pp.486~490 (2018)
  15. Habibi N, "Prevalence of primary dysmenorrhea and factors with its intensity among undergraduate students : a cross sectional study", Pain Manag Nurs, 16, pp.855~861 (2015)
  16. Iacovides S, "What we know about primary dysmenorrhea today : a critical review", Hum Reprod Update, 21, pp.762~778 (2015)
  17. Salehi A, "Effect of foeniculum vulgare on primary dysmenorrhea: a systematic review and metaanalysis", Womens Health Bull (2018)
  18. Karacin O, "Serum vitamin D concentrations in young Turkish women with primary dysmenorrhea : a randomized controlled study", Taiwan J Obstet Gynecol, 57, pp.58~63 (2018)
  19. Zarei S, "Effects of calcium-vitamin d and calcium-alone on pain intensity and menstrual blood loss in women with primary dysmenorrhea : a randomized controlled trial", Pain Med, 18, pp.3~13 (2017)
  20. Hamideh Pakniat, "Comparison of the effect of vitamin E, vitamin D and ginger on the severity of primary dysmenorrhea: a single-blind clinical trial", Obstetrics & Gynecology Science, 62(6), pp.462~468 (2019), 대한산부인과학회[DOI]
  21. Abdul-Razzak KK, "Influence of dietary intake of dairy products on dysmenorrhea", J Obstet Gynaecol Res, 36, pp.377~383 (2010)
  22. Rahnemaie FS, "Relationship between serum vitamin D with severity of primary dysmenorrhea and associated systemic symptoms in dormitories students of Shahid Beheshti University of Medical Sciences", Iran J Obstet Gynecol Infertil, 22, pp.44~53 (2019)
  23. Fatemeh Abdi, "A systematic review of the role of vitamin D and calcium in premenstrual syndrome", Obstetrics & Gynecology Science, 62(2), pp.73~86 (2019), 대한산부인과학회
  24. Rahnemaie FS, "Effects of complementary medicine on successful breastfeeding and its associated issues in the postpartum period", Iran J Pediatr, 29, pp.e80180~ (2019)
  25. Zeynali M, "Is there a relationship between serum vitamin D with dysmenorrhea pain in young women?", J Gynecol Obstet Hum Reprod, 48, pp.711~714 (2019)
  26. Abdul-Razzak KK, "Vitamin D and PTH status among adolescent and young females with severe dysmenorrhea", J Pediatr Adolesc Gynecol, 27, pp.78~82 (2014)
  27. Kucukceran H, "The impact of circulating 25-hydroxyvitamin and oral cholecalciferol treatment on menstrual pain in dysmenorrheic patients", Gynecol Endocrinol, 35, pp.53~57 (2019)
  28. Bahrami A, "High dose vitamin D supplementation can improve menstrual problems, dysmenorrhea, and premenstrual syndrome in adolescents", Gynecol Endocrinol, 34, pp.659~663 (2018)
  29. Ayşegül Ö, "A randomized controlled study of vitamin D in the treatment of primary dysmenorrhea", Duzce Med J, 21, pp.32~36 (2019)
  30. Lama A, "Vitamin D supplements as adjunctive therapy with analgesics for primary dysmenorrhea : a randomized clinical trial", Int J Reprod Med Gynecol, 5, pp.004~14 (2019)
  31. Mehrpooya M, "Comparison the effect of fish-oil and calcium supplementation on treatment of primary dysmenorrhea", Rev Recent Clin Trials, 12, pp.148~153 (2017)
  32. Charandabi SM, "Calcium with and without magnesium for primary dysmenorrhea : a double-blind randomized placebo controlled trial", Int J Women Health Reprod Sci, 5, pp.332~338 (2017)
  33. Fareena Begum A., "Study of prevalence of vitamin D deficiency in primary dysmenorrhea and administration of a single oral dose of vitamin D to improve primary dysmenorrhea" (2017), Coimbatore Medical College
  34. Ataee M, "Cholecalciferol for Primary Dysmenorrhea in a College aged Population—A Clinical Trial", J Biol Todays World, 4, pp.54~57 (2015)
  35. Zangene M, "Evaluation of the effects of oral vitamin-d for pelvic pain reduction in primary dysmenorrhea", Iran J Obstet Gynecol Infertil, 16, pp.14~20 (2014)
  36. Lasco A, "Improvement of primary dysmenorrhea caused by a single oral dose of vitamin D: results of a randomized, double-blind, placebocontrolled study", Arch Intern Med, 172, pp.366~367 (2012)
  37. Thys-Jacobs S, "Micronutrients and the premenstrual syndrome : the case for calcium", J Am Coll Nutr, 19, pp.220~227 (2000)
  38. Thys-Jacobs S, "Cyclical changes in calcium metabolism across the menstrual cycle in women with premenstrual dysphoric disorder", J Clin Endocrinol Metab, 92, pp.2952~2959 (2007)
  39. DeLuca HF, "Overview of general physiologic features and functions of vitamin D", Am J Clin Nutr, 80, pp.1689S~1696S (2004)
  40. Anagnostis P, "Vitamin D in human reproduction : a narrative review", Int J Clin Pract, 67, pp.225~235 (2013)
  41. Moreno J, "Regulation of prostaglandin metabolism by calcitriol attenuates growth stimulation in prostate cancer cells", Cancer Res, 65, pp.7917~7925 (2006)
  42. Proctor ML, "Herbal and dietary therapies for primary and secondary dysmenorrhoea", Cochrane Database Syst Rev, pp.CD002124~ (2001)
  43. Das B, "Serum inorganic phosphorus, uric acid, calcium, magnesium and sodium status during uterine changes of menstrual cycle", Int J Biomed Res, 3, pp.209~213 (2012)
  44. Thys-Jacobs S, "Calcium carbonate and the premenstrual syndrome: effects on premenstrual and menstrual symptoms", Am J Obstet Gynecol, 179, pp.444~452 (1998)
  45. Marshall WJ, "Clinical chemistry" (2008), Mosby
  46. Bertone-Johnson ER, "Vitamin D and the occurrence of depression: causal association or circumstantial evidence?", Nutr Rev, 67, pp.481~492 (2009)
  47. Holick MF., "Vitamin D: a D-lightful health perspective", Nutr Rev, 66, pp.S182~S194 (2008)
  48. Hashemipour S, "Vitamin D deficiency and causative factors in the population of Tehran", BMC Public Health, 4, pp.38~ (2004)
  49. Krishnan AV, "Mechanisms of the anti-cancer and anti-inflammatory actions of vitamin D", Annu Rev Pharmacol Toxicol, 51, pp.311~336 (2011)
  50. Bertone-Johnson ER, "Vitamin d for menstrual and pain-related disorders in women : comment on"improvement of primary dysmenorrhea caused by a single oral dose of vitamin D"", Arch Intern Med, 172, pp.367~369 (2012)
  51. Maïmoun L, "Effect of physical activity on calcium homeostasis and calciotropic hormones : a review", Calcif Tissue Int, 85, pp.277~286 (2009)
  52. Baird DD, "Vitamin D and the risk of uterine fibroids", Epidemiology, 24, pp.447~453 (2013)
  53. Latthe PM, "Dysmenorrhoea", BMJ Clin Evid, 2011, pp.0813~ (2011)
  54. Zamani M, "The evaluation of fish oil(Omega-3 fatty acids)efficacy in treatment of primary dysmenorrhea in high school female students in Hamadan", J Gorgan Univ Med Sci, 7, pp.39~42 (2005)
  55. Sadeghi N, "Vitamin E and fish oil, separately or in combination, on treatment of primary dysmenorrhea: a double-blind, randomized clinical trial", Gynecol Endocrinol, 34, pp.804~808 (2018)
  56. Daily JW, "Efficacy of ginger for alleviating the symptoms of primary dysmenorrhea : a systematic review and meta-analysis of randomized clinical trials", Pain Med, 16, pp.2243~2255 (2015)
  57. Rahnama P, "Effect of Zingiber officinale R. rhizomes (ginger) on pain relief in primary dysmenorrhea: a placebo randomized trial", BMC Complement Altern Med, 12, pp.92~ (2012)
  58. Abdi F, "Experiences of individuals with liver cirrhosis a qualitative study", Gastroenterol Nurs, 38, pp.252~257 (2015)

관련 논문AI추천

Vitamin D supplementation for primary dysmenorrhea: a double-blind, randomized, placebo-controlled trialAli Gholamrezaei, Arian Rashidi, Farid Zayeri, Fatemeh Alsadat Rahnemaei, Giti Ozgoli, Maryam Afrakhteh, Mohammad Reza Vafa대한산부인과학회 · Obstetrics & Gynecology Science2021 · 제64권 제4호A systematic review of the role of vitamin D and calcium in premenstrual syndromeFatemeh Abdi, Fatemeh Sadat Rahnemaie, Gity Ozgoli대한산부인과학회 · Obstetrics & Gynecology Science2019 · 제62권 제2호Comparison of the effect of vitamin E, vitamin D and ginger on the severity of primary dysmenorrhea: a single-blind clinical trialFatemeh Ranjkesh, Hamideh Pakniat, Mohammad Ali Hosseini, Venus Chegini대한산부인과학회 · Obstetrics & Gynecology Science2019 · 제62권 제6호The effect of antioxidant supplementation on dysmenorrhea and endometriosis-associated painful symptoms: a systematic review and meta-analysis of randomized clinical trialsAbdullah Alyousef, Abdulrahim Gari, Ahmed Abu-Zaid, Hussein Sabban, Ibtihal Abdulaziz Bukhari, Khalid Khadawardi, Majed Saeed Alshahrani, Saeed Baradwan대한산부인과학회 · Obstetrics & Gynecology Science2024 · 제67권 제2호Primary Dysmenorrhea: Pathophysiology, Diagnosis, and Treatment UpdatesDeema Rahme, Hani M J Khojah, Lama Soubra, Lina Karout, Rania Itani, Samar Karout대한가정의학회 · Korean Journal of Family Medicine2022 · 제43권 제2호Effect of Curcumin on Dysmenorrhea and Symptoms of Premenstrual Syndrome: A Systematic Review and Meta-AnalysisAzizi Faeze, Mohaghegh Zeynab, Qaderi Kowsar, Sharifipour Foruzan, Siahkal Shahla Faal, Zahedian Maryam대한가정의학회 · Korean Journal of Family Medicine2024 · 제45권 제2호

이 간행물의 다른 논문 (5건)

Prenatal ultrasonographic findings of esophageal atresia: potential diagnostic role of the stomach shapeChi-Son Chang, 노정래, 성지희, 이상훈, 오수영, 이청아, 김미나, 김서연, 최석주, Jeong-Meen Seo, Yunsun Choipp. 42-51The effects of maternal body mass index and plurality on maternal and umbilical cord serum magnesium levels in preterm birth at less than 32 weeks of gestationJee Youn Hong, Cheong-Rae Roh, Suk-Joo Choi, Hyeseon Kim, Soo-young Oh, So Yoon Ahn, 장윤실, 성세인, Ji-Hee Sung, Yoo-Min Kim, Yun Sun Choi, Ji Young Hongpp. 62-72Impact of lymphadenectomy on the treatment of endometrial cancer using data from the JSOG cancer registrySatoru Nagase, Takayuki Enomoto, Daisuke Aoki, Mikio Mikami, Masanori Kaneuchi, Tsutomu Tabata, Yoichi Kobayashi, Keiko Saotome, Wataru Yamagami, Hiroko Machida, Yasuhiko Ebinapp. 80-89Dietary pattern and risk of endometrioma in Korean women: a case-control studyDong Soo Suh, Hyun Joo Lee, Hye Kyung Noh, Seung Chul Kim, Ki Hyung Kim, Jong-Kil Joopp. 99-106Endometrial polyps: Is the prediction of spontaneous regression possible?Suleyman Salman, Hale Goksever Celik, Guray Tuna, Semra Yukselpp. 114-121
원문 보기