Endometrial polyps: Is the prediction of spontaneous regression possible?
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ObjectiveEndometrial polyps have been considered as a hyperplastic growth of endometrial stromal and glandular tissues. Even asymptomatic polyps in premenopausal women are usually removed as soon as they are diagnosed, although itis still unknown how often endometrial polyps disappear spontaneously. The aim of this study was to investigate theregression rate of endometrial polyps and the possible factors related to their spontaneous regression. MethodsA total of 197 women with endometrial polyps were treated with operative hysteroscopy between January 2017 andApril 2019 at our tertiary center. Of these, 123 patients who preferred conservative follow-up were enrolled in thestudy. Clinical and pathological data were obtained from electronic medical records. ResultsPatients with endometrial polyps were followed up for a median period of 62 days (range 30–360 days). Most womenwith endometrial polyps (84%) were reported to have gynecologic symptoms. Spontaneous polyp regression wasobserved in 28 (23%) patients who underwent surgery reevaluation. Patient age (<45 years), premenopausal period,and polyp size (<2 cm) were found to be associated with spontaneous endometrial polyp regression (P<0.05). Wealso observed more polyp regression in women with abnormal uterine bleeding (P=0.05). Second-look hysteroscopyshowed that all postmenopausal women had persistent endometrial polyps. ConclusionPatient age (<45 years), premenopausal period, polyp size (<2 cm), and abnormal uterine bleeding may be associatedwith spontaneous endometrial polyp regression.
Abstract
ObjectiveEndometrial polyps have been considered as a hyperplastic growth of endometrial stromal and glandular tissues. Even asymptomatic polyps in premenopausal women are usually removed as soon as they are diagnosed, although itis still unknown how often endometrial polyps disappear spontaneously. The aim of this study was to investigate theregression rate of endometrial polyps and the possible factors related to their spontaneous regression. MethodsA total of 197 women with endometrial polyps were treated with operative hysteroscopy between January 2017 andApril 2019 at our tertiary center. Of these, 123 patients who preferred conservative follow-up were enrolled in thestudy. Clinical and pathological data were obtained from electronic medical records. ResultsPatients with endometrial polyps were followed up for a median period of 62 days (range 30–360 days). Most womenwith endometrial polyps (84%) were reported to have gynecologic symptoms. Spontaneous polyp regression wasobserved in 28 (23%) patients who underwent surgery reevaluation. Patient age (<45 years), premenopausal period,and polyp size (<2 cm) were found to be associated with spontaneous endometrial polyp regression (P<0.05). Wealso observed more polyp regression in women with abnormal uterine bleeding (P=0.05). Second-look hysteroscopyshowed that all postmenopausal women had persistent endometrial polyps. ConclusionPatient age (<45 years), premenopausal period, polyp size (<2 cm), and abnormal uterine bleeding may be associatedwith spontaneous endometrial polyp regression.
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