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A systematic review of the role of vitamin D and calcium in premenstrual syndrome

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초록

Premenstrual syndrome (PMS) is a common disorder that affects millions of women of reproductive age worldwide. In recent years, there has been a focus on finding accessible, acceptable, and cost-effective therapeutic approacheswith minimal side effects to treat the symptoms of PMS. This systematic review aimed to investigate the role ofcalcium and vitamin D in Premenstrual syndrome. The PubMed, EMBASE, Web of Science, Scopus, Science Direct, andGoogle Scholar databases were systematically searched for relevant articles from clinical trial, case-control, and crosssectionalstudies. The Strengthening the Reporting of Observational Studies in Epidemiology checklist was used toassess the quality of the selected papers. A total of 28 eligible high-quality papers were reviewed. Low serum levelsof calcium and vitamin D during the luteal phase of the menstrual cycle were found to cause or exacerbate thesymptoms of PMS. Therefore, the administration of calcium and vitamin D supplements or the use of a diet rich inthese two substances can restore serum levels and eliminate or reduce the symptoms of PMS. Calcium and vitamin Dsupplementation are recommended as an inexpensive, low-risk, acceptable, and accessible approach to eliminate orreduce the symptoms of PMS.

Abstract

Premenstrual syndrome (PMS) is a common disorder that affects millions of women of reproductive age worldwide. In recent years, there has been a focus on finding accessible, acceptable, and cost-effective therapeutic approacheswith minimal side effects to treat the symptoms of PMS. This systematic review aimed to investigate the role ofcalcium and vitamin D in Premenstrual syndrome. The PubMed, EMBASE, Web of Science, Scopus, Science Direct, andGoogle Scholar databases were systematically searched for relevant articles from clinical trial, case-control, and crosssectionalstudies. The Strengthening the Reporting of Observational Studies in Epidemiology checklist was used toassess the quality of the selected papers. A total of 28 eligible high-quality papers were reviewed. Low serum levelsof calcium and vitamin D during the luteal phase of the menstrual cycle were found to cause or exacerbate thesymptoms of PMS. Therefore, the administration of calcium and vitamin D supplements or the use of a diet rich inthese two substances can restore serum levels and eliminate or reduce the symptoms of PMS. Calcium and vitamin Dsupplementation are recommended as an inexpensive, low-risk, acceptable, and accessible approach to eliminate orreduce the symptoms of PMS.

참고문헌 (64)

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