Carbohydrate, Lipid Inhibitory Activity and Antioxidant Activity of Extracts from Several Economic Resource Plants in Vitro
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초록
The objective of this study was determined to evaluate α‐amylase, α‐glucosidase, pancreatic lipase inhibition invitro and DPPH radical scavenging activity of the several Korean resources plants. The α‐amylase inhibitory activity ofSalicornia herbacea, Erythronium japonicum (flower) and Phragmites communis (root) in water extract showed relativelyhigh 62.8%, 66.5% and 69.3%, respectively. The α‐amylase inhibitory activity of Citrus junos (pericarp) and Cornusofficinalis in methanol extract was found to have an effect with 32.8% in Citrus junos (pericarp) and 60.9% in Cornusofficinalis. Corylopsis coreana in both water and methanol extract had the highest α‐glucosidase inhibitory activity of81.7% and 89.5%, while the extract of Portulaca oleracea, Ficus carica and Citrus junos was not measured α‐glucosidaseinhibitory activity at given experiment concentration. Depending on the extraction solvent and the plant species, it wasobserved that there was a significant difference in α‐glucosidase inhibitory activity. The pancreatic lipase inhibitory activityshowed relatively higher in the methanol extract than water extract except pericarp of Citrus junos. The DPPH radicalscavenging activity of selected plants was much difference between measured plant species, and showed that the increasewas proportional to the concentration. These results suggested that selected plants had the potent biological activity oncarbohydrate, lipid Inhibitory activity and antioxidant activity, therefore these plant resources could be a good materials todevelop medicinal preparations, nutraceuticals or health functional foods for diabetes or obesity.
Abstract
The objective of this study was determined to evaluate α‐amylase, α‐glucosidase, pancreatic lipase inhibition invitro and DPPH radical scavenging activity of the several Korean resources plants. The α‐amylase inhibitory activity ofSalicornia herbacea, Erythronium japonicum (flower) and Phragmites communis (root) in water extract showed relativelyhigh 62.8%, 66.5% and 69.3%, respectively. The α‐amylase inhibitory activity of Citrus junos (pericarp) and Cornusofficinalis in methanol extract was found to have an effect with 32.8% in Citrus junos (pericarp) and 60.9% in Cornusofficinalis. Corylopsis coreana in both water and methanol extract had the highest α‐glucosidase inhibitory activity of81.7% and 89.5%, while the extract of Portulaca oleracea, Ficus carica and Citrus junos was not measured α‐glucosidaseinhibitory activity at given experiment concentration. Depending on the extraction solvent and the plant species, it wasobserved that there was a significant difference in α‐glucosidase inhibitory activity. The pancreatic lipase inhibitory activityshowed relatively higher in the methanol extract than water extract except pericarp of Citrus junos. The DPPH radicalscavenging activity of selected plants was much difference between measured plant species, and showed that the increasewas proportional to the concentration. These results suggested that selected plants had the potent biological activity oncarbohydrate, lipid Inhibitory activity and antioxidant activity, therefore these plant resources could be a good materials todevelop medicinal preparations, nutraceuticals or health functional foods for diabetes or obesity.
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