Immune Cells Activity, Cytotoxicity and Nitrite Scavenging Activity of Extracts from Several Resource Plants
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This study was conducted to explore the immune activity, anticancer activity and nitrile scavenging activities ofmethanol extracts from the various organs of four Korean resource plants. The immune responses from both human T andB cell line was significantly enhanced in the cell growth compared to control while the cell growth was influenced at acertain period of culture. The results revealed that the cell growth of both human T and B cell was altered in a time dependentmanner. Among tested several resource plants, the flower extract of E. japonicum demonstrated a pronounced cytotoxicityagainst HCT-116 cell with an IC50 value 132.08 ㎍ ㎖-1. The flower extract from Corylopsis coreana had a promisingscavenging activity against pH 1.2 compared to other species. Taken together, the studied resource plants have influencedsignificantly in response to immunity and also have the potential cytotoxicity and nitric scavenging activities. However, thespecies E. japonicum exhibited the pronounced activities from several resource plants. The result from this investigationsuggests that the extracts of studied resource plant could be an addition to basic medicine for some diseases.
Abstract
This study was conducted to explore the immune activity, anticancer activity and nitrile scavenging activities ofmethanol extracts from the various organs of four Korean resource plants. The immune responses from both human T andB cell line was significantly enhanced in the cell growth compared to control while the cell growth was influenced at acertain period of culture. The results revealed that the cell growth of both human T and B cell was altered in a time dependentmanner. Among tested several resource plants, the flower extract of E. japonicum demonstrated a pronounced cytotoxicityagainst HCT-116 cell with an IC50 value 132.08 ㎍ ㎖-1. The flower extract from Corylopsis coreana had a promisingscavenging activity against pH 1.2 compared to other species. Taken together, the studied resource plants have influencedsignificantly in response to immunity and also have the potential cytotoxicity and nitric scavenging activities. However, thespecies E. japonicum exhibited the pronounced activities from several resource plants. The result from this investigationsuggests that the extracts of studied resource plant could be an addition to basic medicine for some diseases.
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