정상 면역인 성인에서 전대장염으로 나타난 거대세포바이러스 장염 1예
A case of cytomegalovirus colitis in an immunocompetent adult presenting as pancolitis
1
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
거대세포바이러스는 대부분 면역기능이 저하된 환자에서 심각한 감염증을 유발하나 드물게 면역기능이 정상인 사람에게도 위장관 병변을 유발할 수 있으며 이러한 경우에는 특별한 치료없이 저절로 호전된다. 저자들은 건강한 성인에서 전대장염의 형태로 고식적인 치료에 반응이 없이 심각한 임상경과를 보인 거대세포바이러스 대장염을 대장내시경과 조직검사로 진단하고 ganciclovir로 치료하였기에 보고하는 바이다.
Abstract
CMV is common cause of life-threatening opportunistic viral infection in immunocompromised patients, especially in transplant recipients and those who are infected with HIV. Although CMV infection is generally asymptomatic in healthy adults, CMV colitis can occur in immunocompetent adults. While the right colon is the most common site of gastrointestinal CMV infection, it is extremely rare for it to involve the whole colon. We report a rare case of cytomegalovirus (CMV) colitis in an immunocompetent adult presenting as pancolitis. The usual course of gastrointestinal CMV infection is self limited in an immunocompetent adult, but our case revealed that conservative treatment was not enough, and the administration of ganciclovir was essential for the improvement of disease.(Korean J Med 70:429-433, 2006)
참고문헌 (17)
- "Gastrointestinal cytomegalovirus disease", 119, pp.924~935 (1993)
- "Cytomegalovirus infection of the alimentary tract:a clinicopathological correlation", 81, pp.944~950 (1986)
- "Self-limited cytomegalovirus colitis in immunocompetent individuals", 94, pp.194~199 (1988)
- "Cytomegalovirus colitis in the immunocompetent host:an overview", 30, pp.559~564 (1998)
- "식도와 대장을 동시에 침범한 거대세포바이러스 감염 1예", 26, pp.26~30 (2003)
- "Infection with cytomegalovirus in patients with inflammatory bowel disease: prevalence, clinical significance and outcome", 53, pp.1155~1160 (2004)
- "Cytomegalovirus colitis during mycophenolate mofetil therapy for Wegener's granulomatosis", 20, pp.468~472 (2000)
- "HIV associated cytomegalovirus colitis as a mimic of inflammatory bowel disease", 37, pp.148~150 (1995)
- "Cytomegalovirus infection of the gastrointestinal tract in non AIDS patients", 88, pp.1882~1886 (1993)
- "Primary cytomegalovirus infection and gastric ulcers in normal host", 36, pp.108~111 (1991)
- "정상 면역 환자에서 발생한 거대세포바이러스 대장염 1예", 35, pp.649~653 (2000)
- "Cell- mediated immunity in experimental cytomegalovirus infection", pp.7~ (1990)
- "Cytomegalovirus infection of gastrointestinal endothelium demonstrated by simultaneous nucleic acid hybridization and immunohistochemistry", 113, pp.461~464 (1989)
- "Cytomegalovirus disease of the gastrointestinal tract in patients without AIDS", 17, pp.644~656 (1993)
- "소화기내시경검사", pp.318~325 (2001), 신흥메드싸이언스
- "Cytomegalovirus inclusions in the gastroduodenal mucosa of patients after renal transplantation", 22, pp.698~701 (1981)
- "Combination foscanet and ganciclovir therapy vs monotherapy for treatment of relapsed cytomegalovirus retinitis in patients with AIDS", 114, pp.23~33 (1996)