전신홍반루푸스에 병발된 하시모토 갑상선염과 재생불량성 빈혈 1예
A case of systemic lupus erythematosus associated with Hashimoto's thyroiditis and aplastic anemia
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초록
전신홍반루푸스는 자가면역질환으로 다양한 장기의 손상을 동반 할 수 있으나 동반될 수 있는 여러 가지 합병증 중 동일한 환자에서 하시모토 갑상선염과 재생 불량성 빈혈이 동시에 병발된 경우로 별다른 합병증 없이 성공적으로 치료를 하여 보고한다.
Abstract
We report a 45-year-old female who presented with azotemia, pancytopenia, pericardial effusion, hypothyroidism, decreased complement and positive ANA and was diagnosed as systemic lupus erythematosus (SLE). She referred to our hospital for the evaluation of azotemia. Bone marrow findings were compatible with aplastic anemia and Hashimoto's thyroiditis was diagnosed. After 3 days of methylprednisolone pulse therapy, the aplastic anemia responded and started to improve. She is visiting our clinic on a regular interval and showing good response to maintenance therapy. Hashimoto's thyroiditis is not rare in SLE, and aplastic anemia is relatively rare in SLE but, SLE that is combined with Hashimoto's thyroiditis and aplastic anemia simultaneously, has not been reported as far as our knowledge concerned. So, we report a case of successful treatment of SLE combined with Hashimoto's thyroiditis and aplastic anemia by steroid and thyroxine.(Korean J Med 70:715-718, 2006)
참고문헌 (15)
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