항갑상선제 치료 중 빈혈과 혈소판감소증으로 발현된 전신성홍반성낭창
A Case of Systemic Lupus Erythematosus Manifested as Anemia and Thrombocytopenia during Antithyroid Drug Treatment
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초록
저자들은 항갑상선제 치료 중 빈혈과 혈소판감소증으로 발현된 전신성홍반성낭창을 경험하였다. 그레이브스병이 있는 39세 여자 환자가 빈혈과 혈소판감소증으로 입원하였다. 환자는 안티로이드로 치료하다 입원 한 달 전 메티마졸로 변경하였다. 가능한 여러 원인에 대해 검사하였고 환자는 신장 이상, 혈액 이상, 항인지질항체와 항핵항체 양성인 것이 발견되었다. 환자는 그레이브스병에 동반된 전신성홍반성낭창으로 진단되었고 스테로이드 치료에 좋은 반응을 보였다.
Abstract
We encountered a patient with systemic lupus erythematosus that manifested as anemia and thrombocytopenia during antithyroid drug treatment. A 39-year-old woman with Graves’ disease was admitted with anemia and thrombocytopenia. She had been treated with propylthiouracil, but had switched to methimazole one month prior to admission. We evaluated many possible causes and found that the patient had renal disorder and hematologic disorder, and was positive for antiphospholipid and antinuclear antibodies. She was diagnosed with systemic lupus erythematosus associated with Graves’ disease and was successfully treated with corticosteroids. (Korean J Med 2012;82:232-235)
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