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루푸스 신염 환자에서 항인지질 항체와 연관된 감염 후대칭적 말초 괴저

Symmetrical Peripheral Gangrene Complicating Escherichia coli Sepsis Associated with Antiphospholipid Antibodies in Lupus Nephritis

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참고문헌

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초록

Antiphospholipid syndrome (APS) is an autoimmune disease that involves vascular thrombosis and pregnancy morbidityassociated with elevated titers of antiphospholipid antibodies. APS can affect any organ and has a variety of clinical manifestations. Infections can be associated with thrombotic events in APS, including the potentially fatal subset catastrophic APS. We report acase of extensive symmetrical peripheral gangrene complicating Escherichia coli sepsis associated with antiphospholipidantibodies in a patient with lupus nephritis.

Abstract

Antiphospholipid syndrome (APS) is an autoimmune disease that involves vascular thrombosis and pregnancy morbidityassociated with elevated titers of antiphospholipid antibodies. APS can affect any organ and has a variety of clinical manifestations. Infections can be associated with thrombotic events in APS, including the potentially fatal subset catastrophic APS. We report acase of extensive symmetrical peripheral gangrene complicating Escherichia coli sepsis associated with antiphospholipidantibodies in a patient with lupus nephritis.

참고문헌 (10)

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  4. Cervera R, "Antiphospholipid syndrome associated with infections: clinical and microbiological characteristics of 100 patients", Ann Rheum Dis, 63, pp.131~1317 (2004)
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  7. 손경민, "말단 괴저를 주소로 내원하여 진단된 전신홍반루푸스 1예", 대한내과학회지, 84(1), pp.141~144 (2013), 대한내과학회
  8. 이혜연, "루푸스 환자에서 비전형적 용혈요독증후군에 합병된 사지 말단부 괴저 1예", Kidney Research and Clinical Practice, 29(3), pp.392~397 (2010), 대한신장학회
  9. Moroni G, "Antiphospholipid antibodies are associated with an increased risk for chronic renal insufficiency in patients with lupus nephritis", Am J Kidney Dis, 43, pp.28~36 (2004)
  10. Choi YS, "Acute renal failure and ischemic bowel disease complicated by acute pyelonephritis in a patient with systemic lupus erythematosus", Korean J Nephrol, 19, pp.740~744 (2000)

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