전신홍반루푸스의 비장경색으로 처음 발현된 항인지질 증후군 1예
Splenic Infarction as the Initial Manifestation of Antiphospholipid Syndrome in a Systemic Lupus Erythematosus Patient
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초록
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. In patients with SLE, the prevalence of antiphospholipidantibodies is considerably higher, and is largely responsible for thrombosis. Splenic infarction is a rare complicationof arterial thrombosis in patients with SLE. It is important to consider splenic infarction in a patient with SLE complaining of leftupper quadrant (LUQ) pain because of the possibility of severe infarction-related complications, such as subcapsular hemorrhageand splenic rupture. We report a case of solitary splenic infarction in a patient with SLE. The only symptom was LUQ pain of 3-dayduration. Lupus anticoagulant activity was positive and abdominal-pelvic computed tomography (CT) was consistent with splenicinfarction. She did not show any other evidence of thrombotic events. The patient was diagnosed with antiphospholipid syndromethat presented as a splenic infarction in a SLE patient.
Abstract
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. In patients with SLE, the prevalence of antiphospholipidantibodies is considerably higher, and is largely responsible for thrombosis. Splenic infarction is a rare complicationof arterial thrombosis in patients with SLE. It is important to consider splenic infarction in a patient with SLE complaining of leftupper quadrant (LUQ) pain because of the possibility of severe infarction-related complications, such as subcapsular hemorrhageand splenic rupture. We report a case of solitary splenic infarction in a patient with SLE. The only symptom was LUQ pain of 3-dayduration. Lupus anticoagulant activity was positive and abdominal-pelvic computed tomography (CT) was consistent with splenicinfarction. She did not show any other evidence of thrombotic events. The patient was diagnosed with antiphospholipid syndromethat presented as a splenic infarction in a SLE patient.
참고문헌 (10)
- Ortel TL, "Thrombosis and the antiphospholipid syndrome", Am Soc Hematol Educ Program, 2005, pp.462~468 (2005)
- Fishman D, "Splenic involvement in rheumatic diseases", Semin Arthritis Rheum, 27, pp.141~155 (1997)
- Arnold MH, "Splenic and renal infarction in systemic lupus erythematosus: association with anti-cardiolipin antibodies", Clin Rheumatol, 7, pp.406~410 (1988)
- Longo D, "Harrison's Principles of Internal Medicine" (2011), McGraw-Hill
- Cervea R, "Morbidity and mortality in systemic lupus erythematosus during a 10-year period: a comparison of early and late manifestations in a cohort of 1,000 patients", Medicine (Baltimore), 82, pp.299~308 (2003)
- Choi BG, "Primary antiphospholipid syndrome presenting with abdominal angina and splenic infarction", Rheumatol Int, 22, pp.119~121 (2002)
- 고경현, "항인지질 증후군과 연관된 급성 췌장염 및 비장 괴사 1예", 대한소화기학회지, 53(1), pp.57~59 (2009), 대한소화기학회
- Park KR, "Isolated splenic infarction in a girl with systemic lupus erythematosus", J Korean Pediatr Soc, 39, pp.562~566 (1996)
- Suh JH, "Isolated splenic infarction in a patient with systemic lupus erythematosus", J Korean Rheum Assoc, 9, pp.304~307 (2002)
- Giannakopoulos B, "How I treat the antiphospholipid syndrome", Blood, 114, pp.2020~2030 (2009)