항응고 치료만으로 호전된 감염 후 파국성 항인지질 증후군 1예
Catastrophic Antiphospholipid Syndrome Improved by Anticoagulation Alone
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초록
저자들은 요로 감염에서 호전 중이던 환자에서 흉부 대동맥 및 상지의 다발성 동맥 내 혈전, 관동맥 내 혈전, 좌심실 내 혈전으로 인한 제증상과 호흡기 증상을 보여 파국성 항인지질 항체 증후군으로 진단 후, 면역억제치료 없이 항응고제 사용 및 고식적 치료만으로 호전된 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.
Abstract
Catastrophic antiphospholipid syndrome (APS) is an accelerated subtype of APS that results in multiorgan failure. Although catastrophic APS represents about 0.8% of all APS cases, it is usually a life-threatening medical condition that requires high clinical awareness. Catastrophic APS has been managed by various therapies, including anticoagulation, corticosteroids, plasma exchange and IV immunoglobulin, but it still has a high mortality rate. A few cases treated by anticoagulation and steroids have been reported in Korea. In this paper, we report a case of catastrophic APS that improved after anticoagulation therapy alone. Thus, we consider hat our case shows another clinical aspect of catastrophic APS. (Korean J Med 2011;80:S319-S324)
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