하대정맥과 양쪽 신정맥의 혈전으로 발견된 루푸스 신염 1예
A case of lupus nephritis with IVC and bilateral renal vein thrombosis
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초록
전신홍반루푸스는 신증후군과 관련하여 또한 질환 자체에 의해서도 혈액응고 이상을 초래하여 혈전증이 발생할 수 있다. 저자들은 측복부 동통으로 내원한 평소 건강하였던 21세 여자 환자에게 여러 가지 검사를 통하여 루푸스 신염에 의한 신증후군 및 양측 신정맥과 하대정맥의 대량의 혈전증을 진단하고 항 응고치료 및 하대정맥 필터를 사용하여 치료하였기에 문헌고찰과 함께 보고하는 바이다.
Abstract
Renal vein and inferior vena cava thrombosis are possible complications of nephrotic syndrome related to either primary glomerulonephritis or glomerulonephritis associated with systemic disease. However, renal vein and inferior vena cava thrombosis associated with systemic lupus erythematosus are rare. We experienced a case of bilateral renal vein and inferior vena cava thrombosis associated with systemic lupus erythematosus. A previously healthy 21-year-old female developed sudden flank pain without edema. Abdominal computed tomography (CT) showed bilateral renal vein and inferior vena cava thrombosis. She was diagnosed with systemic lupus erythematosus with nephrotic syndrome based on the clinical manifestations and laboratory findings. After anticoagulation therapy with heparin and insertion of an inferior vena cava filter, the thrombus improved markedly. There is a possibility of renal vein and inferior vena cava thrombosis in the clinical course of nephrotic syndrome caused by lupus nephritis.
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