삼황세제 가미방 화장품의 아토피 피부염 환자에 대한 임상적 연구
A Clinical Study for the effect of cosmetic cream containing Samwhangsejegamibang Extracts on Atopic dermatitis patients
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참고문헌
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초록
Objective : The purpose of this study is to investigate the effect of cosmetic cream containing Samwhangsejegamibang Extracts on Atopic dermatitis patients. Methods : A total of 51 patients who visited Wonkwang Oriental Medical Center from April 8th, 2011 to October 8th, 2011 were included in this study. In this study, the patients were treated with Samwhangsejegamibang (experimental group) and placebo group. We observed scorad index, IGA, moisture content of skin, oil content of skin, wrinkled skin and hematological examination for 4 weeks. Results : 1. Comparison of changes in Scorad Index, depending on the perspective, the experimental group showed a statistically significant decline than the placebo group. 2. Comparison of change in IGA, depending on the perspective, the experimental group showed a statistically significant decline than the placebo group. 3. Comparison of change in moisture content, oil content of skin and wrinkled skin, both the experimental group and the placebo group showed level elevation but there was no statistically significant change. 4. Comparison of change in IgE and Eosinophil, both the experimental group and the placebo group showed no statistical significance. Conclusions : Considering the above experiments, it is suggested that cosmetic cream containing Samwhangsejegamibang extracts have a positive effect on atopic dermatitis patients.
Abstract
Objective : The purpose of this study is to investigate the effect of cosmetic cream containing Samwhangsejegamibang Extracts on Atopic dermatitis patients. Methods : A total of 51 patients who visited Wonkwang Oriental Medical Center from April 8th, 2011 to October 8th, 2011 were included in this study. In this study, the patients were treated with Samwhangsejegamibang (experimental group) and placebo group. We observed scorad index, IGA, moisture content of skin, oil content of skin, wrinkled skin and hematological examination for 4 weeks. Results : 1. Comparison of changes in Scorad Index, depending on the perspective, the experimental group showed a statistically significant decline than the placebo group. 2. Comparison of change in IGA, depending on the perspective, the experimental group showed a statistically significant decline than the placebo group. 3. Comparison of change in moisture content, oil content of skin and wrinkled skin, both the experimental group and the placebo group showed level elevation but there was no statistically significant change. 4. Comparison of change in IgE and Eosinophil, both the experimental group and the placebo group showed no statistical significance. Conclusions : Considering the above experiments, it is suggested that cosmetic cream containing Samwhangsejegamibang extracts have a positive effect on atopic dermatitis patients.
참고문헌 (38)
- Gil KM, "Sampson HA. Psychological and social factors of atopic dermatitis", Allergy, 25, pp.39~44 (1989)
- Korean Dermatological Association Textbook Compilation Committee, "5th Edition Dermatology", pp.170~ (2008), Ryomoongak. P. Co
- Ahn SG, "Common skin disease in Koreans", pp.13~ (2009), Doctor's Book
- In-depth analyses of the third korea national health and nutrition examination survey: The health interview and health behavior survey part, "Korea Centers for Disease Control and Prevention", ~ (2007)
- Lee EH, "Diagnosis and Recent advances in treatment of Atopic dermatitis", The Journal of Skin Barrier Research, 12(1), pp.104~ (2010)
- Akdis DA, "Diagnosis and treatment of atopic dermatitis in children and adults. European Academy of allergology and Clinical Immunology", American Academy of Allergy, Asthma and Immunology, J Allergy Clin Immunol, pp.2006, 118[DOI]
- 김동희, "소아의 아토피피부염 관리 실태", Allergy Asthma & Respiratory Diseases, 18(2), pp.39~48 (2008), 대한 소아알레르기 호흡기학회
- 노성민, "아토피피부염 환자에서 APDDR-0801 보습 제품의 병용을 통한 스테로이드 외용제제의 사용 절감 효능", 대한피부과학회지, 49(03), pp.227~233 (2011), 대한피부과학회
- 이지현, "아토피피부염학회 보고서: 한국 아토피피부염의 치료지침", 대한피부과학회지, 44(8), pp.907~913 (2006), 대한피부과학회
- Magin PJ, "Complementary and Alternative Medicine Therapies in Acne, Psoriasis, and Atopic Eczema : Results of a Qualitative Study of Patients' Experiences and Perceptions", J of Alternative & Complementary Medicine, 12(5), pp.451~457 (2006)
- 김혜림, "淸肌消毒湯이 아토피피부염 염증 관련 인자에 미치는 영향", 한의학연구소 논문집, 20(2), pp.41~52 (2012), 한의학연구소
- 정대웅, "石紫解肌湯이 아토피피부염 유관 인자인 산화적 손상과 염증 인자에 미치는 영향", 한의학연구소 논문집, 20(2), pp.53~66 (2012), 한의학연구소
- 이윤정, "외치방인 淸肌敗毒散의 아토피피부염 동물 병태 모델에서의 면역조절작용에 관한 연구", 한의학연구소 논문집, 20(2), pp.1~16 (2012), 한의학연구소
- Weon YH, "Effect of Taklisodok-um and Hwangryunhaedok-tang on Atopic Dermatitis", 박사, pp.2009
- Jung UR, "The Effects of Pyeongwi-sangamibang on NC", Nga mice with atopic dermatitis, Kyung Hee University, 2011
- Han DS, "Effects of SPDJTK(SoPungDo JeokTangKami) and Concurrent Administration of AJ (Atopy cream, Jawoongo) Plus SPDJTK on Atopic Dermatitis-like Skin Lesions in NC", Nga Mouse Induced by BMAC, Dae Jeon University, 2009
- 원영호, "三黃洗劑加減方의 항균, 항염 및 항알레르기 효과에 대한", 한방안이비인후피부과학회지, 18(1), pp.135~153 (2005), 대한한방안이비인후피부과학회
- Sin MK, "Clinical Traditional Herbalogy", pp.172~785 (2002), Yeongnimsa
- Jiangsu College of Traditional Chinese Medicine, "CHM Dictionary", pp.1316~2307 (1992), Daesung Publishing
- Noe JW, "Pharmacy in China clinical", pp.406~1064 (1998), Ren Min Wei Sheng Publishing. Inc
- Hanifin JM, "Diagnostic features of atopic dermatitis", Acta Derm Venereol(Stockh)Suppl, 92, pp.44~47 (1980)
- Kim HJ, "Understanding of skin barrier in atopic dermatitis and integrative therapy", The journal of Skin Barrier Research, 12(1), pp.67~78 (2010)
- Thomas Bieber, "Atopic Dermatitis", Annals of Dermatology, 22(2), pp.125~137 (2010), 대한피부과학회
- Aubert-Wastiaux H, "Topical corticosteroid phobia in atopic dermatitis : a study of its nature, origins and frequency", British journal of dermatology, 165(4), pp.808~814 (2011)
- 김수찬, "피부외용제에 의한 부작용 사례 연구", 대한피부과학회지, 41(9), pp.1129~1135 (2003), 대한피부과학회
- Baumann L, "Topical glucocorticoids, In Dermatology in general medicine. 6th ed", pp.2324~2328 (2003), McGraw-Hill
- Kim HJ, "Allergen and skin barrier in atopic disease", The Journal of Skin Barrier Research, 10(2), pp.38~45 (2008)
- Schiffner R, "Treatment of atopic dermatitis and impact on quality of life : a review with emphasis on topical non-corticosteroids", Parmacoeconomics, 21(3), pp.159~179 (2003)
- Yang JH, "A study of Eastern-Western medicine on Atopic dermatitis", Daegu Hanny University Jeahan Oriental Medical Academy Journal, 4(1), pp.416~ (1999)
- Chao YF, "Treatise on Pathogenesis and Manifestations of All Diseases", pp.251~253 (1992), Daesung Munhwasa
- Sun SM, "Emergency preparedness Qian Jin Yao Fang", pp.408~409 (1989), Daesung Munhwasa
- Park DB, "Effect of Yanghyeoljeseuptang(YHJST) Composition on Atopic DermatitisNC", Nga Mice Induced by DNCB(dinitrochlorobenzene), Dae Jeon University, 2008
- Kang GM, "Prescription Dictionary", pp.68~ (1991), Uiseongdan
- Choi YS, "The Study on Clinical Features and Laboratory Findings According to the Severity of Atopic Dermatitis", 석사, pp.2005
- Kaliner M, "Rhinitis and asthma", JAMA, pp.2807~29 (1992)
- Yamashita N, "Soluble E-selectin as a marker of desease activity in atopic dermatitis", J allergy Clin Immunol, 99, pp.410~416 (1997)
- Uehara M, "Blood eosinophilia in atopic dermatitis", Clin Exp Dermatol, 15, pp.264~266 (1990)
- 김명남, "아토피 피부염에서 말초 혈액내 호산구 수, 혈청 총 IgE, eosinophil cationic protein, IL-4 및 soluble E-selectin의 변화", 대한피부과학회지, 40(11), pp.1367~1373 (2002), 대한피부과학회