경증의 아토피 환자에서 한약 추출물 함유외용제에 대한 임상 연구
A Clinical Study for the Effect of External Applications Containing Herbal Extracts on Mild Atopic Dermatitis Patients
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Objectives : The purpose of this study is to confirm the effects of external applications(CLANCHE SM A Clinic)containing herbal extracts on patient with atopic dermatitis. Methods : A total of 24 patients who visited Semyung Oriental Medical Center from January 15th, 2014 toFebruary 20th, 2014 were included in the study. In this study, the patients were treated with externalapplications(CLANCHE SM A Clinic) containing herbal extracts. For 4 weeks of gross examination and instrumentalassesment were made before and after the study. Results : 1. In the primary endpoint, SCORAD index showed a statistically significant decline. 2. In the secondary endpoint, index of skin hydration and index of TEWL showed statisticalsignificance. 3. In the secondary endpoint, index of skin pH showed no statistically significant result. 4. To evaluate the safety of the products for the human body, vital sign check were conducted andshowed no statistically significant result. And There were no severe adverse events during this study. Therefore, it is suggested that the safety of the products, if used for certain period, should be safefor the human body. 5. In global assesment of efficacy, both experimenter and subjects evaluated external applications wereeffective. Conclusions : According to the above experiments, it is suggested that external applications(CLANCHE SM AClinic) containing herbal extracts should be effective for the atopic dermatitis.
Abstract
Objectives : The purpose of this study is to confirm the effects of external applications(CLANCHE SM A Clinic)containing herbal extracts on patient with atopic dermatitis. Methods : A total of 24 patients who visited Semyung Oriental Medical Center from January 15th, 2014 toFebruary 20th, 2014 were included in the study. In this study, the patients were treated with externalapplications(CLANCHE SM A Clinic) containing herbal extracts. For 4 weeks of gross examination and instrumentalassesment were made before and after the study. Results : 1. In the primary endpoint, SCORAD index showed a statistically significant decline. 2. In the secondary endpoint, index of skin hydration and index of TEWL showed statisticalsignificance. 3. In the secondary endpoint, index of skin pH showed no statistically significant result. 4. To evaluate the safety of the products for the human body, vital sign check were conducted andshowed no statistically significant result. And There were no severe adverse events during this study. Therefore, it is suggested that the safety of the products, if used for certain period, should be safefor the human body. 5. In global assesment of efficacy, both experimenter and subjects evaluated external applications wereeffective. Conclusions : According to the above experiments, it is suggested that external applications(CLANCHE SM AClinic) containing herbal extracts should be effective for the atopic dermatitis.
참고문헌 (16)
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