고주파 저스트레인 골자극 인가용 진동 시스템 개발
Development of the High_frequency and Low_strain Vibration Stimulation System for Stimulating Bone
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
In this study, the system for application of the bone stimulation was implemented using high frequency and low strain method. The whole system consists of the high frequency and low strain vibration stimulation system for stimulating bone, LVDT sensor, and wireless sensor based on tri-axial accelerometer. To evaluate the usefulness of the system, the frequencies and accelerations from function generator were applied to the vibration stimulation system. The range of frequency was 17 Hz, 30 Hz, 45 Hz, 50 Hz and the range of acceleration was set 0.3 g, 0.6 g,1 g, and 2 g. The measured frequencies and acceleration using LVDT (linear variable difference transformer) sensor and 3-axial accelerometer were estimated and compared. The range of frequencies average difference was from 0.0to 0.004 Hz. As the standard deviation of frequencies estimated by LVDT sensor and accelerometer was below 0.03 Hz and the output frequencies of function generator were similar. Also the results of t-test were satisfied with conditions of p > 0.05. And the acquired frequencies and acceleration from vibration measuring device module were estimated and analyzed. As the mean of accelerations was similar to the acceleration applied from function generator. And the standard deviation of acceleration estimated from vibration measuring device module was ranged from 0.019 g to 0.038 g. Also the results of t-test were satisfied with conditions of p > 0.05. Therefore, these results were fairy similar to the acceleration applied from function generator. As a result, the usefulness of the system was confirmed. In a further study, clinical experiment will be carried out with the authorization of IRB (institutional review board) so that appropriate frequency and strain would be investigated in clinical field.
Abstract
In this study, the system for application of the bone stimulation was implemented using high frequency and low strain method. The whole system consists of the high frequency and low strain vibration stimulation system for stimulating bone, LVDT sensor, and wireless sensor based on tri-axial accelerometer. To evaluate the usefulness of the system, the frequencies and accelerations from function generator were applied to the vibration stimulation system. The range of frequency was 17 Hz, 30 Hz, 45 Hz, 50 Hz and the range of acceleration was set 0.3 g, 0.6 g,1 g, and 2 g. The measured frequencies and acceleration using LVDT (linear variable difference transformer) sensor and 3-axial accelerometer were estimated and compared. The range of frequencies average difference was from 0.0to 0.004 Hz. As the standard deviation of frequencies estimated by LVDT sensor and accelerometer was below 0.03 Hz and the output frequencies of function generator were similar. Also the results of t-test were satisfied with conditions of p > 0.05. And the acquired frequencies and acceleration from vibration measuring device module were estimated and analyzed. As the mean of accelerations was similar to the acceleration applied from function generator. And the standard deviation of acceleration estimated from vibration measuring device module was ranged from 0.019 g to 0.038 g. Also the results of t-test were satisfied with conditions of p > 0.05. Therefore, these results were fairy similar to the acceleration applied from function generator. As a result, the usefulness of the system was confirmed. In a further study, clinical experiment will be carried out with the authorization of IRB (institutional review board) so that appropriate frequency and strain would be investigated in clinical field.
참고문헌 (19)
- Osteoporosis Prevalence Report, 1996 and 2015, "National Osteoporosis foundation", ~ (1997)
- G. C. Park, "The implementation of the vibration system for the increase of bone density", Proc. 41th The Korea Society of Medical & Biological Engineering, pp.44~ (2010)
- G. C. Park, "The body vibration control system using LVDT Displacement Transducer", Proc. 42th The Korea Society of Medical & Biological Engineering, pp.30~ (2010)
- Shinji K, "Functional Outcome after Hip Fracture in Japan", Clin Orthop, 348, pp.29~36 (1998)
- Honda, "A High-impact exercise strengthens bone in osteopenic ovariectomized rats with the same outcome as sham rats", Journal of Applied Physiology, 95(3), pp.1032~1037 (2003)
- S.K.Lim, "Osteoporosis", Korean Journal of Medicine, 58(6), pp.698~702 (2000)
- 대한골대사학회 지침 위원회, "골다공증 진단 및 치료 지침 2007", 대한내분비학회지, 23(2), pp.76~108 (2008), 대한내분비학회
- Cauley JA, "Effects of estrogen plus progestin on risk of fracture and bone mineral density: the Women's Health Initiative randomized trial", JAMA, 290(13), pp.1729~1738 (2003)
- Sook-Bin Woo, "Systematic Review; Bisphosphonates and Osteonecrosis of the Jaws", Annals of Internal Med, 144, pp.753~761 (2006)
- Rubin CT, "Osteoregulatory nature of mechanical stimuli: function as a determinant for adaptive remodeling in bone", J. Orthop. Res, 5, pp.300~310 (1987)
- Rubin CT, "Low mechanical signals strengthen long bones", Nature, 412, pp.603~604 (2001)
- Rubin CT, "The anabolic activity of bone tissue, suppressed by disuse, is normalized by bridf exposure to extremely low-magnitude mechanical stumuli", The FASEB Journal, 15, pp.2225~2229 (2001)
- C. Rubin, "Quantity and Quality of Trabecular Bone in the Femur Are Enhanced by a Strongly Anabolic, Noninvasive Mechanical Intervention", JBMR, 17(2), pp.349~357 (2002)
- 고창용, "전신진동이 난소절제술을 시행한 흰쥐 해면뼈에 미치는 영향", 대한체질인류학회지, 20(4), pp.301~309 (2007), 대한체질인류학회
- Flieger J, "Mechanical Stimulation in the Form of Vibration Prevents Postmenopausal Bone Loss in Ovariectomized Rats", Calcif Tissue Int, 63, pp.510~514 (1998)
- R. Garman, "Low-level accelerations applied in the absence of weight bearing can enhance trabecular bone formation", Journal of Orthopaedic Research, 25, pp.732~740 (2007)
- 고창용, "전신진동이 난소절제술을 시행한 흰쥐 해면뼈에 미치는 영향", 대한체질인류학회지, 20(4), pp.301~309 (2007), 대한체질인류학회
- 정희정, "진동운동이 난소절제술을 시행한 흰쥐의 골다공증에 예방에 미치는 효과", 운동과학, 16(3), pp.263~270 (2007), 한국운동생리학회
- J. Y. Yoo, "The measurement of Vibration using Ultra-low Power Wireless system", Proc. 41th The Korea Society of Medical & Biological Engineering, pp.65~ (2010)