본문 바로가기
KERD
논문KCI 등재

Evaluation of Acoustic, Thermal, and Morphological Properties in the Egg White Phantom

2

조회

0

다운로드

0

인용

0

참고문헌

키워드

초록

The egg white phantom is a thermal lesion visualization phantom able to illustrate a thermal lesion. Itis often used to evaluate the performance of HIFU and is less expensive than the BSA phantom. This study determinedthe optimal phantom composition for evaluated therapeutic ultrasound machines by varying the egg white concentrationin the egg white phantom and demonstrated its utility as a therapeutic ultrasound phantom. The egg whitephantom at varying egg white concentrations (10-40% in 10% intervals) was fabricated, and its thermal propertiesand acoustic properties were assessed. In addition, the size and shape of the formed lesion were compared betweenthe egg white phantom and bovine liver tissue according to the electrical power. The results showed that 30% eggwhite phantom was optimal for the performance evaluation due to its thermal and acoustic properties. The generatedthermal lesions formed sequentially as a cigar, ellipse, tadpole, and cone shapes according to the electrical power;a similar tendency was observed in the liver tissue. Hence, we conclude that the egg white phantom will prove usefulin quantitatively evaluating the thermal effects of therapeutic ultrasound.

Abstract

The egg white phantom is a thermal lesion visualization phantom able to illustrate a thermal lesion. Itis often used to evaluate the performance of HIFU and is less expensive than the BSA phantom. This study determinedthe optimal phantom composition for evaluated therapeutic ultrasound machines by varying the egg white concentrationin the egg white phantom and demonstrated its utility as a therapeutic ultrasound phantom. The egg whitephantom at varying egg white concentrations (10-40% in 10% intervals) was fabricated, and its thermal propertiesand acoustic properties were assessed. In addition, the size and shape of the formed lesion were compared betweenthe egg white phantom and bovine liver tissue according to the electrical power. The results showed that 30% eggwhite phantom was optimal for the performance evaluation due to its thermal and acoustic properties. The generatedthermal lesions formed sequentially as a cigar, ellipse, tadpole, and cone shapes according to the electrical power;a similar tendency was observed in the liver tissue. Hence, we conclude that the egg white phantom will prove usefulin quantitatively evaluating the thermal effects of therapeutic ultrasound.

참고문헌 (20)

  1. Radiation effect on characteristics of radiationcopolymerized methacryloyl-L-alanine methyl ester-co-2-hydroxypropyl methacrylate hydrogel and biochemical properties of ovomucoid, "J.S. Yang", Korea Advanced Institute of Science and Technology, 22~24 (1996)
  2. A. F. Prokop, "Polyacrylamide gel as an acoustic coupling medium for focused ultrasound therapy", Ultrasound Med. Biol, 29, pp.1351~1358 (2003)
  3. L. S. Bouchard, "Magnetic resonance imaging of thermal coagulation effects in a phantom for calibrating thermal therapy devices", Med. Phys, 27, pp.1141~1145 (2000)
  4. C. Lafon, "Gel phantom for use in High-intensity focused ultrasound dosimetry", Ultrasound Med. Biol, 31, pp.1383~1389 (2005)
  5. H. Ushijima, "Measurements of HIFU-induced Lesions in BSA Gel Phantoms for HIFU Treatment of Varicose Veins of Lower Extremity", Proc. AIP Conf., pp.53~58 (2011)
  6. K. Takegami, "Polyacrylamide gel containing egg white as new model for irradiation experiments using focused ultrasound", Ultrasound Med. Biol, 30, pp.1419~1422 (2004)
  7. V. A. Khokhlova, "Effects of nonlinear propagation, cavitation, and boiling in lesion formation by high intensity focused ultrasound in a gel phantom", J. Acoust. Soc. Am, 119, pp.1834~1848 (2006)
  8. J. Gao, "Simultaneous measurement of thermophysical properties of tissuemimicking phantoms for High Intensity Focused Ultrasound(HIFU)exposures", Int. J. Thermophys, 33, pp.480~489 (2012)
  9. Y. Liu, "Egg white as a blood coagulation surrogate", J. Acoust. Soc. Am, 128, pp.480~489 (2010)
  10. G.W. Divkovic, "Egg white phantom for HIFU", Proc. AIP Conf., pp.143~146 (2004)
  11. G. W. Divkovic, "Thermal properties and changes of acoustic parameters in an egg white phantom during heating and coagulation by High Intensity Focused Ultrasound", Ultrasound Med. Biol, 33, pp.981~986 (2007)
  12. C. P. Labuda, "Augmentation of HIFUinduced heating with fibers embedded in a phantom", Ultrasound Med. Biol, 3, pp.442~449 (2011)
  13. S. R. Davidson, "Measurement of the thermal conductivity of polyacrylamide tissue equivalent material", Int. J. Hyperthermia, 19, pp.551~562 (2003)
  14. M. G. Bini, "The polyacrylamide as a phantom material for electromagnetic hyperthermia studies", IEEE Trans. Biomed. Eng., BME-31, pp.317~322 (1984)
  15. "Medical electrical equipment-Particular requirements for the basic safety and essential performance of ultrasonic physiotherapy equipment", International Electrotechnical Commission, 21~ (2009)
  16. "Tissue substitutes, phantoms and computational modelling in medical ultrasound", International Commission on Radiation Units and Measurements, 1~132 (1998)
  17. T.D. Mast, "Empirical relationships between acoustic parameters in human soft tissues", J. Acoust. Soc. Am, 1, pp.37~42 (2000)
  18. J.Y. Kim, "A study for the Analysis of thermal denature characteristic on tissue by using Egg-white TMM phantom", Proc. 48th Biomedical Engineering, pp.57~58 (2013)
  19. C. R. Hill, "Review article: High intensity focused ultrasound-potential for cancer treatment", The British J. Radiology, 68, pp.1296~1303 (1995)
  20. D. Haemmerich, "In vitro measurements of temperature-dependent specific heat of liver tissue", Medical Engineering &Physics, 28, pp.194~197 (2006)

관련 논문AI추천

이 간행물의 다른 논문 (4건)