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Successful Treatment of Recalcitrant Primary Follicular Mucinosis with Indomethacin and Low-dose Intralesional Interferon Alpha

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초록

Follicular mucinosis (FM) is an epithelial reaction pattern thatis characterized by the accumulation of mucinous material inthe epithelial hair follicle sheath and the sebaceous glands. Although various pharmacological agents have been employedin an attempt to treat FM, effective therapeuticoptions have remained elusive. We experienced a recalcitrantform of primary FM that we successfully treated withindomethacin and low-dose intralesional interferon alpha(IFN α), respectively. To the best of our knowledge, theprimary type of FM that responded to indomethacin andlow-dose IFN α, respectively, in a single case has not beenreported in the English medical literature.

Abstract

Follicular mucinosis (FM) is an epithelial reaction pattern thatis characterized by the accumulation of mucinous material inthe epithelial hair follicle sheath and the sebaceous glands. Although various pharmacological agents have been employedin an attempt to treat FM, effective therapeuticoptions have remained elusive. We experienced a recalcitrantform of primary FM that we successfully treated withindomethacin and low-dose intralesional interferon alpha(IFN α), respectively. To the best of our knowledge, theprimary type of FM that responded to indomethacin andlow-dose IFN α, respectively, in a single case has not beenreported in the English medical literature.

참고문헌 (15)

  1. Pinkus H, "Alopecia mucinosa; inflammatory plaques with alopecia characterized by root-sheath mucinosis", AMA Arch Derm, 76, pp.419~424 (1957)
  2. Jablonska S, "Mucinosis follicularis", Hautarzt, 10, pp.27~33 (1959)
  3. Emmerson RW, "Follicular mucinosis. A study of 47 patients", Br J Dermatol, 81, pp.395~413 (1969)
  4. Yotsumoto S, "A case of follicular mucinosis treated successfully with minocycline", Br J Dermatol, 142, pp.841~842 (2000)
  5. Kodama H, "Follicular mucinosis: response to indomethacin", J Dermatol, 15, pp.72~75 (1988)
  6. Kubba RK, "Follicular mucinosis responding to dapsone", Br J Dermatol, 91, pp.217~220 (1974)
  7. Meissner K, "Successful treatment of primary progressive follicular mucinosis with interferons", J Am Acad Dermatol, 24, pp.848~850 (1991)
  8. Hempstead RW, "Follicular mucinosis. A reaction pattern in follicular epithelium", Am J Dermatopathol, 7, pp.245~257 (1985)
  9. Reed RJ, "The T-lymphocyte, the mucinous epithelial interstitium, and immunostimulation", Am J Dermatopathol, 3, pp.207~214 (1981)
  10. Takematsu H, "Eosinophilic pustular folliculitis. Studies on possible chemotactic factors involved in the formation of pustules", Br J Dermatol, 114, pp.209~215 (1986)
  11. Morley J, "Regulation of allergic responses by prostaglandins: a review", J R Soc Med, 73, pp.443~447 (1980)
  12. Martinez J, "Long-term results of intralesional interferon alpha-2B in discoid lupus erythematosus", J Dermatol, 20, pp.444~446 (1993)
  13. Yoshida R, "Agonist and antagonist effects of interferon alpha and beta on activation of human macrophages. Two classes of interferon gamma receptors and blockade of the high-affinity sites by interferon alpha or beta", J Exp Med, 167, pp.1171~1185 (1988)
  14. Saito H, "Effect of human interferon on different functions of human neutrophils and eosinophils", Int Arch Allergy Appl Immunol, 82, pp.133~140 (1987)
  15. Aldebert D, "Eosinophils express a functional receptor for interferon alpha: inhibitory role of interferon alpha on the release of mediators", Blood, 87, pp.2354~2360 (1996)

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