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Papular Mucinosis Associated withSystemic Lupus Erythematosus

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주제분류피부과학

초록

Papulonodular mucinosis (PNM) is a rare variant of lupus erythematosus (LE) eruptions, and PNM is characterized histologically by diffuse dermal mucin without any typical epidermal inflammatory changes. We herein describe a case of papular mucinosis that was characterized by several erythematous papules on the lower back of a 32-year-old man with systemic LE. It is interesting that he didn't display any other skin manifestations of LE such as malar rash, discoid rash and photosensitivity during the previous 2 years. He achieved remission of his PNM without recurrence after 5 months treatment with topical steroids, in addition to receiving systemic antimalarials and steroids.

Abstract

Papulonodular mucinosis (PNM) is a rare variant of lupus erythematosus (LE) eruptions, and PNM is characterized histologically by diffuse dermal mucin without any typical epidermal inflammatory changes. We herein describe a case of papular mucinosis that was characterized by several erythematous papules on the lower back of a 32-year-old man with systemic LE. It is interesting that he didn't display any other skin manifestations of LE such as malar rash, discoid rash and photosensitivity during the previous 2 years. He achieved remission of his PNM without recurrence after 5 months treatment with topical steroids, in addition to receiving systemic antimalarials and steroids.

참고문헌 (10)

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  2. 박준수, "피부 루푸스 점액증 1예", 대한피부과학회지, 42(8), pp.1073~1075 (2004), 대한피부과학회
  3. Sonntag M, "Papulonodular mucinosis associated with subacute cutaneous lupus erythematosus", Dermatology, 206, pp.326~329 (2003)
  4. Lowe L, "Papulonodular dermal mucinosis in lupus erythematosus", J Am Acad Dermatol, 27, pp.312~315 (1992)
  5. Choi EH, "Papulonodular cutaneous mucinosis associated with systemic lupus erythematosus", Int J Dermatol, 31, pp.649~652 (1992)
  6. Kanda N, "Cutaneous lupus mucinosis: a review of our cases and the possible pathogenesis", J Cutan Pathol, 24, pp.553~558 (1997)
  7. Williams WL, "Acute periorbital mucinosis in discoid lupus erythematosus", J Am Acad Dermatol, 41, pp.871~873 (1999)
  8. Kobayashi T, "Plaquelike cutaneous lupus muci nosis", Arch Dermatol, 129, pp.383~384 (1993)
  9. Kano Y, "Nodular cutaneous lupus mucinosis: report of a case and review of previously reported cases", Cutis, 57, pp.441~444 (1996)
  10. Pandya AG, "Papulonodular mucinosis associated with systemic lupus erythematosus: possible mechanisms of increased glycosaminoglycan accumulation", J Am Acad Dermatol, 32, pp.199~205 (1995)

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