Two Clinically Unusual Cases of Folliculotropic Mycosis Fungoides: One with and the Other without Syringotropism
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Mycosis fungoides is the most common form of cutaneousT-cell lymphoma, and it rarely exhibits predilection for hairfollicle and eccrine gland infiltration. Here, we present 2similar cases that display folliculotropism with varyingamounts of follicular mucinosis, with and without syringotropism. The features observed in both cases were cystic,comedo-like, acneiform lesions; generalized involvementwith loss of body hair; pruritus; and hidradenitis suppurativa-like lesions. Hypohidrosis as well as nail and palmoplantarinvolvement with lichen planopilaris-like clinicalfeatures were unique characteristics of the first case. Despitethe well-known aggressive behavior of follicular mycosisfungoides, the presented cases had a subtle, slowly progressive,but persistent, clinical course. Folliculotropic andsyringotropic mycosis fungoides are variants of cutaneousT-cell lymphoma. Clinical presentations might be challenging,and multiple, deep biopsy specimens containingadnexal structures are required for this critical diagnosis. Aggressive treatment may not be necessary in cases havingan indolent course, especially in those with syringotropism.
Abstract
Mycosis fungoides is the most common form of cutaneousT-cell lymphoma, and it rarely exhibits predilection for hairfollicle and eccrine gland infiltration. Here, we present 2similar cases that display folliculotropism with varyingamounts of follicular mucinosis, with and without syringotropism. The features observed in both cases were cystic,comedo-like, acneiform lesions; generalized involvementwith loss of body hair; pruritus; and hidradenitis suppurativa-like lesions. Hypohidrosis as well as nail and palmoplantarinvolvement with lichen planopilaris-like clinicalfeatures were unique characteristics of the first case. Despitethe well-known aggressive behavior of follicular mycosisfungoides, the presented cases had a subtle, slowly progressive,but persistent, clinical course. Folliculotropic andsyringotropic mycosis fungoides are variants of cutaneousT-cell lymphoma. Clinical presentations might be challenging,and multiple, deep biopsy specimens containingadnexal structures are required for this critical diagnosis. Aggressive treatment may not be necessary in cases havingan indolent course, especially in those with syringotropism.
참고문헌 (20)
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