Extensive Nevus Comedonicus with Inflammatory Nodules and Cysts Controlled with Adalimumab
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Nevus comedonicus is a very rare skin disorder characterized by the presence of comedo-like dilated pores with keratinous plugs, rarely resulting in painful recurrent inflammatory nodules or cysts. It presents as localized or extensive form. It displays unilaterally or bilaterally segmental distribution. Histopathologically, it is characterized by keratin- filled epidermal invagination with bulbous proliferation of keratinocytes. The condition may be caused by fibroblast growth factor receptor 2 mutation. Although it may be controlled by a variety of therapeutic modalities, it is difficult to achieve complete resolution. We report a case of extensive nevus comedonicus with inflammatory nodules and cysts controlled with adalimumab.
Abstract
Nevus comedonicus is a very rare skin disorder characterized by the presence of comedo-like dilated pores with keratinous plugs, rarely resulting in painful recurrent inflammatory nodules or cysts. It presents as localized or extensive form. It displays unilaterally or bilaterally segmental distribution. Histopathologically, it is characterized by keratin- filled epidermal invagination with bulbous proliferation of keratinocytes. The condition may be caused by fibroblast growth factor receptor 2 mutation. Although it may be controlled by a variety of therapeutic modalities, it is difficult to achieve complete resolution. We report a case of extensive nevus comedonicus with inflammatory nodules and cysts controlled with adalimumab.
참고문헌 (20)
- Bolognia JL, "Dermatology", pp.109~ (2008), Mosby Elsevier
- Bongiorno MR, "Naevus comedonicus immunohistochemical features in two cases", Acta Derm Venereol, 83, pp.300~301 (2003)
- Manikavachakan N, "Extensive nevus comedonicus, complicated with recurrent abscesses, successfully treated with surgical resurfacing", J Cutan Aesthet Surg, 11, pp.33~37 (2018)
- 정한진, "Two Concurrent Facial Epidermal Nevi without Systemic Abnormalities: Nevus Sebaceus and Nevus Comedonicus", Annals of Dermatology, 26(4), pp.501~504 (2014), 대한피부과학회
- 함승필, "Case Study of Extensive Nevus Comedonicus in a Middle-aged Woman", 대한피부과학회지, 57(4), pp.230~232 (2019), 대한피부과학회
- Milton GP, "Treatment of nevus comedonicus with ammonium lactate lotion", J Am Acad Dermatol, 20(2 Pt 2), pp.324~328 (1989)
- Decherd JW, "Naevus comedonicus--treatment with retinoic acid", Br J Dermatol, 86, pp.528~529 (1972)
- Manola I, "Nevus comedonicus--case report and review of therapeutical approach", Acta Dermatovenerol Croat, 11, pp.221~224 (2003)
- Deliduka SB, "Treatment of nevus comedonicus with topical tazarotene and calcipotriene", J Drugs Dermatol, 3, pp.674~676 (2004)
- Peck GL, "Treatment of lamellar ichthyosis and other keratinising dermatoses with an oral synthetic retinoid", Lancet, 2, pp.1172~1174 (1976)
- Gulliver W, "Evidence-based approach to the treatment of hidradenitis suppurativa", acne inversa, based on the European guidelines for hidradenitis suppurativa, 2016, pp.17, 343~351
- Caers SJ, "Successful treatment of nevus comedonicus with the use of the erbium Yag laser", J Eur Acad Dermatol Venereol, 22, pp.375~377 (2008)
- Sardana K, "Successful treatment of nevus comedonicus with ultrapulse CO2 laser", Indian J Dermatol Venereol Leprol, 75, pp.534~535 (2009)
- Moody MN, "1,450-nm diode laser in combination with the 1550-nm fractionated erbium-doped fiber laser for the treatment of steatocystoma multiplex: a case report", Dermatol Surg, 38(7 Pt 1), pp.1104~1106 (2012)
- Liang G, "Anticancer molecules targeting fibroblast growth factor receptors", Trends Pharmacol Sci, 33, pp.531~541 (2012)
- Dinarello CA, "Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases", Nat Rev Drug Discov, 11, pp.633~652 (2012)
- Ohta K, "Autophagy impairment stimulates PS1 expression and gamma-secretase activity", Autophagy, 6, pp.345~352 (2010)
- Sahu P, "Biologic therapy : a boon for hidradenitis suppurativa-like lesions complicating naevus comedonicus in a prepubertal child", Clin Exp Dermatol, 44, pp.322~324 (2019)
- Kimball AB, "Assessing the validity, responsiveness and meaningfulness of the Hidradenitis Suppurativa Clinical Response (HiSCR) as the clinical endpoint for hidradenitis suppurativa treatment", Br J Dermatol, 171, pp.1434~1442 (2014)
- Ravaioli GM, "Congenital nevus comedonicus complicated by a hidradenitis suppurativalike lesion : report of a childhood case", Pediatr Dermatol, 35, pp.e298~e299 (2018)