복합운동에 의한 체중감량 정도의 차이와 심폐체력 및 혈관신생인자 간의 연관성
Correlations of combined exercise-induced weight loss with cardiorespiratory fitness and angiogenesis factors.
1
조회
0
다운로드
4
인용
0
참고문헌
키워드
초록
본 연구의 목적은 비만 중년여성의 대상으로 12주간의 복합운동 후 체중감량 정도의 차이와 심폐체력 및 혈관신생인자 간의 연관성을 조사하는데 있다. 모든 피험자들은 12주 동안 주당 3회의 써킷 웨이트 트레이닝과 주당 5회의 트레드밀 달리기의 유산소 운동을 복합적으로 실시하였다. 12주간의 복합운동 후 피험자들의 체중감량 정도의 차이에 따라 체중감량이 많은 상위 25% 집단(n=11)과 체중감량이 적은 하위 25%(n=11)으로 집단을 구분하였다. 통계분석결과 12주 복합운동 트레이닝은 집단에 상관없이 심폐체력을 유의하게 증가시키는 것으로 나타났지만, 혈관신생인자 중에서도 혈중 VGEF 수준은 상위 25% 집단에서만 유의하게 감소한 것으로 나타났다. 결론적으로, 12주간의 복합운동 실시 후 1) 체중감량 정도의 차이와 심폐체력 간에는 상관관계가 없는 것으로 나타났다. 그리고 2) 체중감량 정도의 차이와 혈중 혈관신생인자(VEGF, PAI-1) 간에는 정적인 상관관계가 있는 것으로 나타났다.
Abstract
The purpose of current study was to investigate the correlations of combined exercise-induced weight loss with cardiorespiratory fitness (CRF) and angiogenesis factors in middle-aged women. The combined exercise program(circuit weight training and aerobic exercise) were provided at a frequency of 3 sessions and 5 sessions, respectively, per week for a duration of 12 weeks. Then, the subjects were classified into either those whose weight loss belonged to low 25 percentile (low 25% group, n=11) or those whose weight loss belonged to high 25 percentile (high 25% group, n=11) based on the amount of weight loss induced by the exercise training. Statistical analyses showed that both groups had significant improvements in CRF. On the other hand, the high 25% group had a significant reduction in serum VEGF and greater improvements in body composition parameters as compared with those of the low 25% group. In conclusion, the findings of the present study are 1) that the combined exercise-induced weight loss were not relate to CRF and 2) that the combined exercise-induced weight loss were positively relate to serum VEGF and PAI-1.
참고문헌 (28)
- 2008년도 국민건강영양조사, "보건복지부", 보건복지부, ~ (2009)
- Amaral, S. L., "Angiotensin II and VEGF are involved in angiogenesis induced by short-term exercise training", Am. J. Physiol. Heart. Circ. Physiol, 281, pp.H1163~H1169 (2001)
- American College of Sports Medicine., "ACSM’s guidelines for exercise testing and prescription. 7th edn", pp.237~240 (2006), Lippinocott Williams & Wilkins
- Astrand, P. O., "Physical performance as a function of age", JAMA, 205(11), pp.729~733 (1968)
- Barbato, A., "Relationships of PAI-1 levels to central obesity and liver steatosis in a sample of adult male population in southern Italy", Intern. Emerg. Med, 4(4), pp.315~323 (2009)
- Barlow, C. E., "Physical activity, mortality, and obesity", Int. J. Obes, 19(suppl), pp.S41~S44 (1995)
- Bloor, C. M., "Angiogenesis during exercise and training", Angiogenesis, 8(3), pp.263~271 (2005)
- Brahimi-Horn, M. C., "Oxygen, a source of life and stress", FEBS. Lett, 581(19), pp.3582~3591 (2007)
- Brixius, K., "Long-term endurance exercise decreases antiangiogenic endostatin signalling in overweight men aged 50-60 years", Br. J. Sports. Med, 42(2), pp.126~129 (2008)
- Bruce, R. A., "Multi-stage treadmill tests of maximal and submaximal exercise. In exercise testing and training of apparentlyhealthy individuals: A Handbook for Physicians", pp.32~34 (1972), American Heart Association
- Carmeliet, P., "Angiogenesis in cancer and other diseases", Nature, 407(6801), pp.249~257 (2000)
- Crowe, S., "Pigment epithelium-derived factor contributes to insulin resistance in obesity", Cell. Metab, 10(1), pp.40~47 (2009)
- Esmat, S., "Effect of exercise on paI-1 level in patients with metabolic syndrome", J. Ameri. Sci., 6(12), pp.1374~1380 (2010)
- García de la Torre, N., "Effects of weight loss after bariatric surgery for morbid obesity on vascular endothelial growth factor-A, adipocytokines, and insulin", J. Clin. Endocrinol. Metab, 93(11), pp.4276~4281 (2008)
- Gómez-Ambrosi, J., "Plasma osteopontin levels and expression in adipose tissue are increased in obesity", J. Clin. Endocrinol. Metab, 92(9), pp.3719~3727 (2007)
- Huttunen, N. P., "Physical activity and fitness in obese children", Int. J. Obes, 10(6), pp.519~525 (1986)
- Kantartzis, K., "High cardiorespiratory fitness is an independent predictor of the reduction in liver fat during a lifestyle intervention in non-alcoholic fatty liver disease", Gut, 58(9), pp.1281~1288 (2009)
- 이종도, "Cardiorespiratory fitness, body composition, and all-cause and cardiovascular disease mortality in men", AMERICAN JOURNAL OF CLINICAL NUTRITION, 69(3), pp.373~380, AMER SOC CLINICAL NUTRITION
- Liu, L., "Angiogenesis inhibitors may regulate adiposity", Nutr. Rev., 61(11), pp.384~387 (2003)
- Loebig, M., "Evidence for a relationship between VEGF and BMI independent of insulin sensitivity by glucose clamp procedure in a homogenous group healthy young men", PLoS One, 5(9), pp.e12610~ (2010)
- Nakamura, K., "Serum levels of pigment epithelium-derived factor (PEDF) are an independent determinant of insulin resistance in patients with essential hypertension", Int. J. Cardiol, 143(1), pp.96~98 (2010)
- Oberbach, A., "Combined proteomic and metabolomic profiling of serum reveals association of the complement system with obesity and identifies novel markers of body fat mass changes", J. Proteome. Res., 10(10), pp.4769~4788 (2011)
- 박현태, "THE EFFECT OF COMBINED EXERCISE TRAINING ON CAROTID ARTERY STRUCTURE AND FUNCTION, AND VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) IN OBESE OLDER WOMEN", JAPANESE JOURNAL OF PHYSICAL FITNESS AND SPORTS MEDICINE, 59(5), pp.495~503, JAPANESE SOC PHYSICAL FITNESS SPORTS MEDICINE
- Pepper, M. S., "Manipulating angiogenesis. From basic science to the bedside", Arterioscler. Thromb. Vasc. Biol, 17(4), pp.605~619 (1997)
- Rowland, T. W., "Effects of obesity on aerobic fitness in adolescent females", Am. J. Dis. Child., 145(7), pp.764~768 (1991)
- Seida, A., "Serum bFGF levels are reduced in Japanese overweight men and restored by a 6-month exercise education", Int. J. Obes. Relat. Metab. Disord, 27(11), pp.1325~1331 (2003)
- Wei, M., "Relationship between low cardiorespiratory fitness and mortality in normal-weight, overweight, and obese men", JAMA, 282, pp.1547~1553 (1999)
- Zanconato, S., "Gas exchange during exercise in obese children", Eur. J. Pediatr, 148(7), pp.614~617 (1989)