Effects of Combined EXERCISE Training on Obesity Indices and VEGF and Endothelin-1 in Obese Middle-Aged Women
1
조회
0
다운로드
6
인용
0
참고문헌
키워드
초록
The purpose of this study was to examine the effects of combined exercise training for 16 weeks on obesity indices and artery intima media thickness and cardiovascular risk factors in obese middle-aged women. The subjects of this study were obese middle-aged women of 45-48 years old. They were divided into a control group(n=17) and a combined exercise group(n=14). In the combined exercise group, a combined exercise consisting of walking and resistance exercise for 16 weeks has been conducted. The results showed that there was no significant difference of change in the BMI but WHR was significantly decreased in the combined exercise group compared to the control group. VEGF levels were significantly increased after the exercise in the combined exercise group compared to before the exercise. Endothelin-1 levels were significantly decreased after the exercise in the combined exercise group compared to before the exercise.
Abstract
The purpose of this study was to examine the effects of combined exercise training for 16 weeks on obesity indices and artery intima media thickness and cardiovascular risk factors in obese middle-aged women. The subjects of this study were obese middle-aged women of 45-48 years old. They were divided into a control group(n=17) and a combined exercise group(n=14). In the combined exercise group, a combined exercise consisting of walking and resistance exercise for 16 weeks has been conducted. The results showed that there was no significant difference of change in the BMI but WHR was significantly decreased in the combined exercise group compared to the control group. VEGF levels were significantly increased after the exercise in the combined exercise group compared to before the exercise. Endothelin-1 levels were significantly decreased after the exercise in the combined exercise group compared to before the exercise.
참고문헌 (25)
- Gavin TP, "Effect of Short-term Exercise Training on Angiogenic Growth Factor Gene Responses in Rats", Journal of Applied Physiology, 90(4), pp.1219~1226 (2001)
- David CN, "Reducing Diet and", or Ex-ercise Training Decreases the Lipid and Lipoprotein Risk Factors of Moderately Obese Women, 2002, pp.21(4), 344~350
- Ministry of Health and Welfare, "2012 Sta-tistical Yearbook of Health and Welfare" (2012)
- 정수진, "유산소 운동이 흡연 성인남성의 혈중 Nitric Oxide 및 Endothelin-1 농도 및 동맥경직도에 미치는 영향", 한국생활환경학회지, 20(1), pp.72~80 (2013), 한국생활환경학회
- Belabbas H, "Contrasting Effect of Exercise and Angi-otensin II Hypertension on in Vivo and In vitro Cardiac Angiogenesis in Rats", Ameri-can Journal of Physiology, 295, pp.1512~1518 (2008)
- Camsari A, "Endothelin-1 and Nitric Oxide Concentrations and Their Response to Exercise in Patients with Slow Coronary Flow", Circulation, 67(12), pp.1022~1028 (2003)
- 김형돈, "비만 중년여성들의 복합운동 프로그램이 비만관련인자에 미치는 영향", 한국사회체육학회지, (45), pp.811~820 (2011), 한국사회체육학회
- ACSM, "ACSM’s Guidelines for Exercise Testing and Prescription" (2008), Hanmi Medical
- 허선, "영양교육피드백과 복합운동을 병행한 행동수정이 비만 여고생의 대사증후군 관련인자, 아디포사이토카인 및 식이섭취 변화에 미치는 영향", 한국체육학회지, 51(2), pp.441~451 (2012), 한국체육학회[DOI]
- Berg BR, "Di-rect Coupling between Blood Flow and Metabolism at the Capillary Level in Stri-ated Muscle", American Journal of Physiol-ogy, 272, pp.2693~2700 (1997)
- Inoue A, "The Human Preproendothelin-1 Gene, Com-plete Nucleotide Sequence and Regulation of Expression", The Journal of Biological Chemistry, 264(25), pp.14954~14959 (1989)
- Amaral SL, "Exercise Training Normalizes Wall-to-lu-men Ratio of the Gracilis Muscle Arteri-oles and Reduces Pressure in Spontane-ously Hypertensive Rats", Journal of Hyper-tens, 18, pp.1563~1572 (2000)
- Hansen AH, "Exercise Training Normalizes Skeletal Muscle Vascular Endothelial Growth Factor Levels in Patients with Es-sential Hypertension", Journal of Hyperten-sion, 28(6), pp.1176~1185 (2010)
- Maeda S, "Effects of Exercise Training of 8 Weeks and Detraining on Plasma Levels of Endothelium-derived Factors, Endothelin-1 and Nitric Oxide, in Healthy Young Humans", Life Science, 69(9), pp.1005~1016 (2001)
- Maeda S, "Aerobic Exercise Training Reduces Plasma Endo-thelin-1 Concentration in Older Woman", Journal of Applied Physiology, 95(1), pp.336~341 (2003)
- Gustafsson T, "In-creased Expression of VEGF Following Ex-ercise Training in Patients with Heart Fail-ure", European Journal of Clinical Investiga-tion, 31(4), pp.362~366 (2001)
- Hudlicka O, "Adaptation of Skeletal Muscle Microvasculature to In-creased or Decreased Blood Flow: Role of Shear Stress, Nitric Oxide and Vascular En-dothelial Growth Factor", Journal of Vasca-lar research, 46(5), pp.504~512 (2009)
- Kohzuki M, "Localizat-gion of Endothelin Receptors in Rat Kid-ney", European Journal of Pharmacology, 160(1), pp.160~193 (1989)
- Newman WP, "Autopsy Studies in United States Children and Adolescents. Relationship of Risk Factors to Atherosclerotic Lesions", Annals New York Academy of Sciences, 623(1), pp.16~25 (1991)
- Miyauchi T, "Pathophysiology of Endothelin in the Cardiovascular Sys-tem", Annual. Review of Physiology, 61(1), pp.391~415 (1999)
- Takuwa Y, "Endothelin-1 Acti-vates Phospho-lipase C and Mobilizes Ca** from Extra-and Intracellular Pools in Osteoblastic Cells", American Journal of Physiologyl, 257, pp.797~803 (1989)
- Silha JV, "Angiogenic Factors are Elevated in Overweight and Obese Individuals", Inter-national Journal of Obesity, 29(11), pp.1308~1314 (2005)
- Yanagisawa M, "Primary Structure, Synthesis, and Biological Activity of Rat Endothelin, an Endothelium-derived Vaso-constrictor Peptide", Proc Natl Acad Sci. USA, 85(18), pp.6964~6967 (1988)
- Tanabe K, "Physiological Role of Endothelin-1 in Non-working Muscle during Exercise in Healthy Subjects", Japanese. Circulation Journal, 64(1), pp.27~31 (2000)
- Neufeld G, "Vascular Endothelial Growth Factor(VEGF) and Its Receptors", The FASEB Journal, 13(1), pp.9~22 (1999)
