Rehmanniae Radix, an Effective Treatment for Patients with Various Inflammatory and Metabolic Diseases: Results from a Review of Korean Publications
2
조회
0
다운로드
5
인용
0
참고문헌
키워드
초록
Objectives: This study was a review of the literature published on the efficacy of Rehmanniae Radix to obtain information to provide both a foundation for its clinical use and directions for future studies. Methods: This study selected 30 publications registered to databases or published in Korea by March 13, 2017, by searching electronic journal databases, i.e., NDSL, OASIS, RISS, and KISS, in order to review the efficacy of Rehmanniae Radix. The search was conducted using the keywords ‘生地黃’, ‘鮮地黃’, ‘Rehmannia Glutinosa’, and ‘Rehmanniae Radix’, and the search results were compiled and analyzed. Results: The selected publications included antioxidant effects (12 publications), data involving blood glucose reduction (4 publications), effects on the autonomic nervous system (3 publications), and effects on the human body (11 publications). Conclusion: The results of this literature review indicate that Rehmanniae Radix is effective in treating patients with various inflammatory and metabolic diseases, such as high blood pressure and diabetes. Based on these results, we believe that Rehmanniae Radix can be used effectively to treat patients with such diseases.
Abstract
Objectives: This study was a review of the literature published on the efficacy of Rehmanniae Radix to obtain information to provide both a foundation for its clinical use and directions for future studies. Methods: This study selected 30 publications registered to databases or published in Korea by March 13, 2017, by searching electronic journal databases, i.e., NDSL, OASIS, RISS, and KISS, in order to review the efficacy of Rehmanniae Radix. The search was conducted using the keywords ‘生地黃’, ‘鮮地黃’, ‘Rehmannia Glutinosa’, and ‘Rehmanniae Radix’, and the search results were compiled and analyzed. Results: The selected publications included antioxidant effects (12 publications), data involving blood glucose reduction (4 publications), effects on the autonomic nervous system (3 publications), and effects on the human body (11 publications). Conclusion: The results of this literature review indicate that Rehmanniae Radix is effective in treating patients with various inflammatory and metabolic diseases, such as high blood pressure and diabetes. Based on these results, we believe that Rehmanniae Radix can be used effectively to treat patients with such diseases.
참고문헌 (38)
- Yook CS, "Herbal medicineⅡ", pp.141~ (1992), Gwangmyunguihagsa Publishers
- Shin MK, "Clinical herb", pp.218~ (1986), Namsandang Publishers
- Lee SI, "Clinical application of Korean medicine", pp.199~201 (1986), Sungbosa Publishers
- Shin JY, "Bangyag-Habpyeon commentary", pp.152~ (2008), Sungbosa Publishers
- 서형식, "靑黛와 生地黃의 항염 및 항산화 효과에 대한 실험적 연구", 한방안이비인후피부과학회지, 21(3), pp.104~110 (2008), 대한한방안이비인후피부과학회
- 채병숙, "Regulatory Effect of Fresh Rehmanniae Radix Extract on the in Vitro Productionof Proinflammatory Cytokines in Pristane-Induced Lupus Mice", Natural Product Sciences, 13(4), pp.322~327 (2007), 한국생약학회
- 강경화, "Inhibitory Effect of Rehmannia Glutinosa Pharmacopuncture Solution on β-hexosaminidase Release and Cytokine Production via FcεRI signaling in RBL-2H3 Cells", Journal of Pharmacopuncture, 14(2), pp.15~24 (2011), 대한약침학회
- Shin KS, "The effect of rhemanniae radix extract on allergic contact dermatitis on mice induced by DNCB", Korean J Orientaln Medical Prescription, 8(1), pp.257~279 (2000)
- 조영제, "숙지황(Rehmannia glutinosa) 추출물의 생리활성", 생명과학회지, 22(7), pp.943~949 (2012), 한국생명과학회[DOI]
- Yong-Hee Lee, "Anti-Apoptotic Effects of Catalpol on Preimplantaion Porcine Embryos", 한국수정란이식학회지, 30(1), pp.23~31 (2015), 한국수정란이식학회
- Chang Hyun Jin, "Anti-inflammatory Activities of Ethylacetate Extract of Rehmannia glutinosa in LPS-induced RAW 264.7 Cells", Food Science and Biotechnology, 18(4), pp.923~927 (2009), 한국식품과학회
- 문유란, "Antioxidant Enzyme Responses against Abiotic and Biotic Stresses in Rehmannia glutinosa L. and Gycine max L.", 한국약용작물학회지, 12(5), pp.360~365 (2004), 한국약용작물학회
- Lim JD, "Biological activities of resveratrol-3-O-ß-D-giucoside in transgenic Rehmanniae Radix", J Plant Biotechnol, 5(1), pp.129~ (2005)
- 강경화, "Rehmannia Glutinosa Pharmacopuncture Solution Regulates Functional Activation, FcεRI Expression, and Signaling Events in Mast Cells", Journal of Pharmacopuncture, 15(4), pp.32~41 (2012), 대한약침학회[DOI]
- 채병숙, "사이토카인 생산에 미치는 생지황메탄올추출물의 효과", 약 학 회 지, 50(3), pp.184~190 (2006), 대한약학회
- 김성범, "生地黃이 혈관신생, 세포생존 및 염증관련 단백질발현에 미치는 영향", 한방안이비인후피부과학회지, 19(3), pp.22~33 (2006), 대한한방안이비인후피부과학회
- 김혜정, "Antidiabetic, Antioxidative and Renoprotective Effects of Rehmanniae Radix preparata Extract in Streptozotocin-induced Diabetic Rats", 대한의생명과학회지, 14(1), pp.19~26 (2008), 대한의생명과학회
- 김정상, "생지황(Rehmanniae Radix)과 배의 Phenolic Compound가 Streptozotocin으로 유발된 고혈당 생쥐에 미치는 영향", 한국식품영양과학회지, 33(1), pp.66~71 (2004), 한국식품영양과학회
- 김정상, "생지황(Rhemanniae Radix)이 Streptozotocin으로 유발된 고혈당 생쥐에 미치는 영향", 한국식품영양과학회지, 33(7), pp.1133~1138 (2004), 한국식품영양과학회
- Jeong HJ, "The effects of rehmanniae radices extracts on streptozotocin-induced hyperglycemia in rats", J Research Institute of Pharmacy, 4(1), pp.22~31 (1990)
- Yook Taehan, "Comparing the Effects of Distilled Rehmannia glutinosa, Wild Ginseng and Astragali Radix Pharmacopuncture With Heart Rate Variability (HRV): A Randomized, Sham-controlled and Double-blind Clinical Trial", Journal of Acupuncture & Meridian Studies, 2(3), pp.239~247 (2009), 사단법인약침학회
- 신진철, "생지황 약침이 정상인의 심박변이도(HRV)에 미치는 영향", Journal of Pharmacopuncture, 11(1), pp.83~97 (2008), 대한약침학회
- Lee HY, "The effects of distilled Astragali Radix herbal acupuncture, wild ginseng herbal acupuncture and Rehmannia Glutinosa herbal acupuncture on vital sign; a randomized, placebo-controlled, double-blind clinical trial", The Acupuncture, 24(5), pp.207~217 (2007)
- 이봄비, "Rehmannia glutinosa Ameliorates Scopolamine-Induced Learning and Memory Impairment in Rats", Journal of Microbiology and Biotechnology, 21(8), pp.874~883 (2011), 한국미생물·생명공학회
- 박재범, "生地黃이 강제수영부하시험에서 HPA Axis System과 Catecholaminergic System에 미치는 영향", 대한한의학 방제학회지, 18(1), pp.133~144 (2010), 대한한의학방제학회
- 허종원, "生地黃 증류 추출 약침액과 초임계 유체 추출물의 성분 硏究", Journal of Acupuncture Research, 28(2), pp.89~95 (2011), 대한침구의학회
- Shin MS, "The effects of Rehmanniae Radix on the propulsive peristalsis of the rat’s gastrointestine", Kor J Herbol, 16(1), pp.189~199 (2001)
- 김주연, "生地黃이 子宮頸部癌細胞(HeLa cell)에 미치는 影響", 대한한방부인과학회지, 19(1), pp.69~80 (2006), 대한한방부인과학회
- Park JB, "Effects of Rehmannia glutinosa aqua - acupuncture at the meridian ponits BL23 on the renal function in two-kidney one clip goldblatt hypertensive rats", The Acupuncture, 11(1), pp.225~239 (1994)
- 이금홍, "補血 藥材인 당귀, 지황, 백작약, 하수오의 면역 촉진 효과 비교 분석", 동의생리병리학회지, 20(6), pp.1507~1515 (2006), 한의병리학회
- Kwon YD, "Effects of Rhizoma rehmanniae adminstration on the innate and adap tive responses in the mouse", JORM, 8(1), pp.233~254 (1998)
- 김종욱, "감마선 照射 生地黃의 Catapol 성분에 대한 안전성 및 유전독성학적 연구", 생약학회지, 36(2), pp.75~80 (2005), 한국생약학회
- Ki YS, "Effects of Rehmanniae Radix on the rat liver damaged with CCl4", Kor J Herbol, 15(1), pp.45~51 (2000)
- Kwon NW, "An experimental study on the effect of Rehmannise Radix and cirsii herba extract administration to the serum prothrombin time in mouse", J East-West Medical Research Ins, 5(1), pp.259~268 (1982)
- 고성권, "고려인삼의 재배 역사와 본초학적 고증을 통한 인삼 기미 고찰", 대한본초학회지, 24(3), pp.169~172 (2009), 대한본초학회
- 남기열, "고려인삼의 주요 효능과 그 임상적 응용", Journal of Ginseng Research, 26(3), pp.111~131 (2002), 고려인삼학회
- 윤유식, "연근별 황기의 항산화 및 항당뇨 활성 평가 고찰", 생약학회지, 40(1), pp.1~5 (2009), 한국생약학회
- 신현상, "백하오이중탕의 基源, 變遷, 構成에 대한 考察", 사상체질의학회지, 23(2), pp.164~173 (2011), 사상체질의학회
