어린이 음료가 레진계 치면열구전색제의 화학적 분해에 미치는영향
The Effect of Children’s Beverages on Degradation of Dental Resin-Based Pit and Fissure Sealant
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초록
시판 중인 어린이 음료가 레진계 치면열구전색제에 미치는 물리 화학적 영향을 알아보기 위해 판매량이 높은 3종의어린이 음료와 대조군으로 생수를 선정하였다. 제조사의 지시에 따라 레진 시편을 제작하여 시편의 초기 거칠기 값(Ra) 를 측정하였고, 각 음료의 pH를 측정한 후, 레진 시편을 각각의 음료에 침지시켜 37oC 배양기에서 72시간 보관하였다. 72시간 후 레진 시편의 표면 거칠기를 측정하였고 시편표면의 형태변화 관찰을 위해 주사전자현미경으로 관찰하였다. 레진 시편에서 용출된 단량체의 종류 및 용출량은HPLC를 이용하여 비교 분석하였다. 생수를 제외한 모든 실험음료에 구연산이 첨가되어 있었고 어린이 음료의 평균pH는 3.25±0.17로 ‘아이키커’에서 3.03±0.01로 가장 낮았고 ‘뽀로로’에서 3.47±0.02로 가장 높았다. 어린이 음료에침지 후 시간 경과에 따른 표면 거칠기가 증가하였고 레진시편의 표면에 기질의 탈락을 관찰하였다. 모든 실험음료에서 bis-GMA는 유출되지 않았으나 생수를 제외한 어린이음료에서는 TEGDMA가 유출되었다. 이상의 결과 어린이음료는 치면열구전색제의 열화와 단량체의 유리를 촉진할 수 있으며 유리된 단량체는 성장 중인 어린이에게 더 큰 영향을 미칠 수 있으므로 어린이 음료를 빈번히 음용하는 것은 주의가 필요하다.
Abstract
The consumption of beverages among children is rising. The purpose of this study was to examine the effect of kid’s drink on dental resin-based pit and fissure sealant. Pororo, I-kicker, Sunkist kids were included in the experimental groups, and Samdasu was included in the control group. A conventional dental sealant material (ClinproTMSealantⓇ) was selected for this study. Resin specimens (8 mm in diameter and 1 mm in thickness) were prepared according to manufacturers’ instructions and the initial roughness (Ra) was then measured. The pH of all the four groups was measured using a pH meter. The specimens were individually immersed in 5 ml of the experimental solutions and stored at 37oC for 72 hours. Following this, the surface roughness of the resin specimens was measured by Surftest. The concentration of residual monomer released was determined by high performance liquid chromatography (HPLC). The surface morphology of the resin specimen was evaluated before and after storage by scanning electron microscopy (SEM). Data were statistically analyzed using Kruskal-Wallis and Duncan’s test. The results showed that all the children’s beverages examined in this study contained citric acid. The pH of I-kicker was the lowest (3.03±0.01), followed by that of Sunkist kids (3.26±0.02) and Pororo (3.47±0.02). We observed an increase in the surface roughness of resin specimens after 72 h of immersion in all the beverages tested (p＜0.05). There was matrix degradation after immersion, visualized on SEM image, in all the beverage groups. Bisphenol-A-glycidyl methacrylate was not detected after 72 hours, but triethylene glycol dimethacrylate levels were increased in all the beverages tested during the 72 hours by HPLC. These results suggest that intake of beverages containing acid can cause degradation of the resin-based pit and fissure sealants in children.
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