사료중 크릴 밀을 급여한 육계의 생산성과 SOD활성에 미치는 급성기반응의 영향
Effect of the Acute Phase Response on the Performance and Superoxide Dismutase Activity in Broiler Chicks Fed on Dietary Krill Meal
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초록
급성 기 반응중인 육계에서 사료 중 크릴 밀의 생산성과 SOD 활성에 미치는 영향을 조사하기 위하여 크릴 밀 A와 B를 이용한 실험 1과 크릴 밀 A를 이용한 확인 실험 2가 실시 되었다. 실험사료는 옥수수 대두박 위주의 기초 사료 와 기초 사료 중 대두박과 2.0%의 크릴 밀 A(수입) 또는 크릴 밀 B(수입)를 대치한 사료이다. 실험 사료를 1 일령 육계 병아리에 급여하여 Salmonella typhymurium lipopolysaccharide (LPS)를 복강 내 주입하여 급성 기 반응을 발생시킨 2 주령 육계의 생산성과 Superoxide dismu- tase(SOD) 활성에 미치는 영향을 Saline을 주입한 대조와 비교하였다. 증체량, 사료 섭취량 및 사료효율은 크릴 밀 A와 크릴 밀 B 사료를 급여한 육계사이에 차이가 있었다. 크릴 밀 사료를 급여한 육계에서 급성기 반응은 간장과 비장 무계를 높였다. 그리고 급성기 반응은 크릴 밀 사료를 급여한 육계 병아리의 간장과 적혈구 세포액의 MnSOD와 Cu/ZnSOD 활성을 높였다. PHA-p 반응에 미치는 크릴 밀 사료의 영향은 없었다. 크릴 밀 B는 면역반응 후 회복중인 육계의 생산성을 향상시켰으나 크릴 밀 A에서는 이러한 영향이 없었다.이상과 같이 크릴 밀의 종류에 따라 급성기반응시 와 회복시의 생산성은 SOD 활성의 변화로부터 산화 스트레스의 영향을 받고 있다는 것을 시사하고 있다.
Abstract
Two experiments were conducted to examine the effects of the acute phase response on the performance and superoxide dismutase(SOD) activities in liver and erythrocyte of broiler chicks fed dietary krill meals A and B in experiment 1 and krill meal A in experiment 2. The experimental diets are basal diet based on yellow corn and soybean meal and diets substituted 2.0% of krill meal A or B with soybean meal of the basal diet, respectively. Day-old birds fed on the experimental diets and the acute phase response(immunological stress) was activated in the birds on 8-day of age by alternate day injection i.p. with 3 doses the Salmonella typhymurium lipopolysaccharide(LPS) in saline. The values during the acute phase response were compared with those controls injected with saline. The performance; daily gain, feed intake, and feed efficiency were different between dietary krill meal A and B in birds during the acute phase response and in the control. The acute phase response increased relative liver and spleen weights. Recovery of birds from the immunological stress was different between krill meals. Dietary krill meals increased activities of MnSOD and Cu/ZnSOD in erythrocyte cytosols during the actute phase response. Dietary krill meals did not affect the PHA-p response. The results indicated that the dietary krill meals may accentuate oxidative stress during the acute phase response.
참고문헌 (25)
- "Metabolic and nutritional consequence of infection Advances in Nutritional Research", pp.~1 (1977)
- "Dietary energy source and density modulate the expression of immunologic stress in chicks", pp.1714~1723 (1993)
- "Evaluation of cell-mediated cutaneous basophil hypersensitivity in young chikckens by an interdigital skin test", pp.403~408 (1990)
- "The fatty acid signature of carnivouous Antartic krill Euphausia superba.", pp.23~27, University of California Santa
- "Primary and secondary wattle swelling response to phytohemagglutinin as a measure of immunocompetence in chicken", pp.105~111 (1985)
- "Changes in macrophage and lymphocyte functions in guinea-pigs after different amounts of vitamin E ingestion", 84, pp.25~29 (2000)
- "Mechanisms of oxidant stress- induced acute tissue injury", 209, pp.104~111 (1995)
- "Influence of cell sources and incubation conditions on release of interleukin-1 from chicken macrophages", pp.385~394 (1987)
- "Avian macrophages: Regulator of local and systeminc immune responses", 77, pp.983~989 (1998)
- "Decreased amino acid requirement of growing chicks due to immunologic stress", 118, pp.1158~1164 (1988)
- "Dietary copper level affects copper metabolism during lipopolysaccharide-induced immunological stress in chicks", 75(7), pp.867~872 (1996)
- "Squid liver oil modulate immunological stress in broiler chicks", 22, pp.59~69 (2001), Konkuk University
- "Dietary fish oil alters specific and inflammatory immune response in chicks", 127, pp.2039~2046 (1997)
- "The phenomenon of the acute phase response", pp.39~48 (1982)
- "Protein mesurement with the Folin phenol reagent", pp.265~275 (1954)
- "Involvement of the superoxide anion radical in the autooxidation of pyrogallol and a convenient assay for superoxide dismutase", pp.469~474 (1974)
- "An enzyme function for erythrocuprein", pp.6049~6055 (1969)
- "Nutrient Requirements of Poultry" (1994), National Academy Press
- "Changes in tissue growth concentration of copper cytochrome oxidase and superoxide dismutase subsequent to dietary or genetic copper deficiency in mice", pp.2148~2158 (1983)
- "Prevention of immunologic stress contributes to the growth-permitting ability of dietary antibiotics in chicks", pp.2383~2390 (1992)
- "Regulation of manganese superoxide dismutase by lipopolysaccharide role in the acute inflamatory response", pp.2856~1 2864 (1990)
- "Effects of Salmonella typhymurium lipopolysacchride on broiler chickens", 79, pp.33~40 (2000)
- "Effect of carotenoids on the respiratory burst of rat peritoneal macrophages", 1381, pp.77~88 (1998)
- "살모네라 LPS로 자극한 육계의 면역반응과 생산성에 미치는 사료 중 크릴 밀의 영향", 46(2), pp.173~182 (2004)
- "살모네라 LPS로 자극한 육계의 단백질과 에너지 이용성에 미치는 사료 중 크릴 밀의 영향", 45, pp.957~966 (2003)