본문 바로가기
KERD
논문

Effects of hot-melt extruded nanocopper on the Cu bioavailability and growth of broiler chickens

2

조회

0

다운로드

2

인용

0

참고문헌

키워드

주제분류축산학

초록

This study was aimed to investigate the Cu bioavailability, growth response, digestibility of nutrients, and blood metabolites of broiler chicks fed CuSO4 in nano or common forms. A total of 720 broiler chickens were distributed between eight treatments according to a completely randomized design. There were 8 treatments and 6 replicates in each treatment with 15 birds/replicate. The treatments were divided into common copper sulfate at the doses of 16 ppm, 40 ppm, 80 ppm, and 120 ppm (INO) and hot-melt extruded copper sulfate at the doses of 16 ppm, 40 ppm, 80 ppm, and 120 ppm (HME-Cu). The experiment was operated for 35 days in 2 phases (phase 1, d 0 to 14; and phase 2, d 15 to 35). No significant differences were shown in growth performance, feed intake, FCR, and nutrient digestibility among the treatments. The concentration of Cu in the serum was increased in the HME-Cu broilers compared with the INO broilers at phase 2. A linear increase was observed in the concentration of Cu in the liver in broilers fed INO diets, however, no significant differences were observed by the supplementation of HME-Cu levels. The linear increase was detected in the content of Cu in excreta in the INO and HME-Cu treatments by increasing the dietary Cu content. The HME-Cu treatments showed a lower Cu concentration in the excreta compared with the INO treatments. The higher bioavailability of Cu in HME form can decrease the recommended dose of Cu in broiler diets.

Abstract

This study was aimed to investigate the Cu bioavailability, growth response, digestibility of nutrients, and blood metabolites of broiler chicks fed CuSO4 in nano or common forms. A total of 720 broiler chickens were distributed between eight treatments according to a completely randomized design. There were 8 treatments and 6 replicates in each treatment with 15 birds/replicate. The treatments were divided into common copper sulfate at the doses of 16 ppm, 40 ppm, 80 ppm, and 120 ppm (INO) and hot-melt extruded copper sulfate at the doses of 16 ppm, 40 ppm, 80 ppm, and 120 ppm (HME-Cu). The experiment was operated for 35 days in 2 phases (phase 1, d 0 to 14; and phase 2, d 15 to 35). No significant differences were shown in growth performance, feed intake, FCR, and nutrient digestibility among the treatments. The concentration of Cu in the serum was increased in the HME-Cu broilers compared with the INO broilers at phase 2. A linear increase was observed in the concentration of Cu in the liver in broilers fed INO diets, however, no significant differences were observed by the supplementation of HME-Cu levels. The linear increase was detected in the content of Cu in excreta in the INO and HME-Cu treatments by increasing the dietary Cu content. The HME-Cu treatments showed a lower Cu concentration in the excreta compared with the INO treatments. The higher bioavailability of Cu in HME form can decrease the recommended dose of Cu in broiler diets.

참고문헌 (25)

  1. B. Samanta, "The Effects of Copper Supplementation on the Performance and Hematological Parameters of Broiler Chickens", Animal Bioscience, 24(7), pp.1001~1006 (2011), 아세아·태평양축산학회
  2. Abdullah Scott, "Copper nanoparticles as an alternative feed additive in poultry diet: a review", Nanotechnology Reviews, 7(1), pp.69~93 (2018), Walter de Gruyter GmbH[DOI]
  3. Baker DH, "Research note: bioavailability of copper in cupric oxide, cuprous oxide, and in a copper-lysine complex", Poult Sci, 70, pp.177~179 (1991)[DOI]
  4. G.-B. Kim, "Effects of supplemental copper-methionine chelate and copper-soy proteinate on the performance, blood parameters, liver mineral content, and intestinal microflora of broiler chickens", Journal of Applied Poultry Research, 20(1), pp.21~32 (2011), Elsevier BV[DOI]
  5. Close WH, "Biotechnology in the feed industry", pp.469~483 (1998), Nottingham University Press
  6. M. Skřivan, "Effects of dietary zinc, iron, and copper in layer feed on distribution of these elements in eggs, liver, excreta, soil, and herbage", Poultry Science, 84(10), pp.1570~1575 (2005), Elsevier BV[DOI]
  7. A. Scott, "Effect of different levels of copper nanoparticles and copper sulphate on performance, metabolism and blood biochemical profiles in broiler chicken", Journal of Animal Physiology and Animal Nutrition, 102(1), pp.e364~e373 (2018), Wiley[DOI]
  8. Byung-Eun Kim, "Mechanisms for copper acquisition, distribution and regulation", Nature Chemical Biology, 4(3), pp.176~185 (2008), Springer Science and Business Media LLC[DOI]
  9. Luo XG, "Dietary copper and fat on nutrient utilization, digestive enzyme activities, and tissue mineral levels in weanling pigs", J Anim Sci, 74, pp.1888~1896 (1996)[DOI]
  10. JunHyung Lee, "Biological evaluation of hot-melt extruded nano-selenium and the role of selenium on the expression profiles of selenium-dependent antioxidant enzymes in chickens", Biological Trace Element Research, 194(2), pp.536~544 (2020), Springer Science and Business Media LLC[DOI]
  11. Song Lee, "Fabrication and Characterizations of Hot-Melt Extruded Nanocomposites Based on Zinc Sulfate Monohydrate and Soluplus", Applied Sciences, 7(9), pp.902~ (2017), MDPI AG[DOI]
  12. 이준형, "Effects of hot melt extrusion processed nano-iron on growth performance, blood composition, and iron bioavailability in weanling pigs", 한국축산학회지, 61(4), pp.216~224 (2019), 한국축산학회[DOI]
  13. 황일환, "Advances in hot-melt extrusion technology toward pharmaceutical objectives", Journal of Pharmaceutical Investigation, 47(2), pp.123~132 (2017), 한국약제학회
  14. Association of Official Analytical Chemists International, "Official methods of analysis of AOAC International" (2007), AOAC International
  15. "Ross broiler: nutrition specifications" (2019)[URL]
  16. C. Wang, "Effects of copper-loaded chitosan nanoparticles on growth and immunity in broilers", Poultry Science, 90(10), pp.2223~2228 (2011), Elsevier BV[DOI]
  17. Liu S, "Copper in organic proteinate or inorganic sulfate form is equally bioavailable for broiler chicks fed a conventional corn–soybean meal diet", Biol Trace Elem Res, 147, pp.142~148 (2012)
  18. Natalia Mroczek-Sosnowska, "In ovoadministration of copper nanoparticles and copper sulfate positively influences chicken performance", Journal of the Science of Food and Agriculture, 96(9), pp.3058~3062 (2016), Wiley[DOI]
  19. Gangadoo S, "Nanoparticles in feed: progress and prospects in poultry research", Trends Food Sci Technol, 58, pp.115~126 (2016)[DOI]
  20. Eleonore Fröhlich, "Models for oral uptake of nanoparticles in consumer products", Toxicology, 291(1-3), pp.10~17 (2012), Elsevier BV[DOI]
  21. Sergey Miroshnikov, "Comparative assessment of effect of copper nano- and microparticles in chicken", Oriental Journal of Chemistry, 31(4), pp.2327~2336 (2015), Oriental Scientific Publishing Company[DOI]
  22. O’hagan DT, "The intestinal uptake of particles and the implications for drug and antigen delivery", J Anat, 189, pp.477~482 (1996)
  23. Naser A. Anjum, "Transport phenomena of nanoparticles in plants and animals", humans, 2016, pp.151, 233~243[DOI]
  24. A.V. Jegede, "Growth response, blood characteristics and copper accumulation in organs of broilers fed on diets supplemented with organic and inorganic dietary copper sources", British Poultry Science, 52(1), pp.133~139 (2011), Informa UK Limited[DOI]
  25. Mroczek-Sosnowska N, "Effect of nanoparticles of copper and copper sulfate administered in ovo on hematological and biochemical blood markers of broiler chickens", Ann Warsaw Univ Life Sci-SGGW. Anim Sci, 52, pp.141~149 (2013)

관련 논문AI추천

Hot-melt extruded copper sulfate affects the growth performance, meat quality, and copper bioavailability of broiler chickens채병조, 호세인, Kim Kwang Yeoul, Kim Min Ju, Kim Tae Gyun, Lee Jun Hyung아세아·태평양축산학회 · Animal Bioscience2022 · 제35권 제3호Effects of dietary copper sources and levels on growth performance, copper digestibility, fecal and serum mineral characteristics in growing pigsByeonghyeon Kim, Hyun Jung Jung, Jin Young Jeong, Min Ji Kim, Seol Hwa Park한국축산학회 · 한국축산학회지2022 · 제64권 제5호Cupric citrate supplementation improves growth performance, nutrient utilization, antioxidant capacity, and intestinal microbiota of broilersJiang Qingkui, Lu Zhentao, Wu Xuezhuang, Zhang Tietao, Zhang Yunting, Zhou Yahao아세아·태평양축산학회 · Animal Bioscience2025 · 제38권 제3호Effects of hot melt extrusion processed nano-iron on growth performance, blood composition, and iron bioavailability in weanling pigs김광열, 김민주, 송창현, 이송이, 이준형, 조현종, 채병조, 최요한, Abdolreza Hosseindoust, Joseph Moturi한국축산학회 · 한국축산학회지2019 · 제61권 제4호Availability of trace minerals in feed ingredients and supplemental sources (inorganic, organic, and nano) in broiler chickensJunhyung Lee, Minju Kim한국축산학회 · 한국축산학회지2025 · 제67권 제4호사료 내 Hot Melt Extrusion 가공된 황산아연의 첨가가 이유자돈의 사양성적, 영양소 소화율, 소장의 형태학적 변화 및 분중 아연 배출에 미치는 영향강위수, 구자성, 김광열, 김민주, 남수영, 심영호, 이송이, 조현종, 채병조, 최요한, Abdolreza Hosseindoust동물생명과학연구소 · 동물자원연구2017 · 제28권 제4호

이 간행물의 다른 논문 (20건)