Effects of hot melt extrusion processed nano-iron on growth performance, blood composition, and iron bioavailability in weanling pigs
2
조회
0
다운로드
6
인용
0
참고문헌
키워드
초록
This study was conducted to investigate the effects of hot melt extrusion (HME) nano-iron as an alternative for the common ferrous sulfate on iron (Fe) bioavailability, growth performance, nutrient digestibility, intestinal morphology, and intestinal microbiota of weanling pigs. A total of 200 piglets (Landrace × Yorkshire × Duroc) were randomly allotted to seven treatments on the basis of initial body weight (BW) and sex. Treatments were the INO100 (100 ppm Fe as FeSO4), HME-Fe levels (50, 75, and 100 ppm nano-Fe as FeSO4). ORG100 (100 ppm Fe as iron methionine). In phase 1, the HME50 pigs showed the lowest Fe content in feed and feces. Plasma Fe concentration was increased in HME100 and ORG100 pigs. In phase 2, there were significantly lower concentration of Fe in feed and feces of HME50 pigs (p < 0.01). A lower Fe concentration in the plasma and liver were observed in HME50 pigs compared with HME100 pigs. Concentration of red blood cell (RBC) was the lowest (p < 0.01) for HME50 pigs. During phase 2, the HME100, HME75, and ORG100 pigs showed a higher RBC and hemoglobin values compared with HME50 pigs. Digestibility of gross energy (GE) and crude protein (CP) were significantly higher in HME100 pigs compared with HME50 pigs. There was an increased (p < 0.01) villus height in the duodenum and jejunum of HME100 pigs compared with HME50 pigs. It is concluded that dietary Fe does not improve growth performance of weanling pigs; however, increasing the dietary iron concentration in weanling piglets increased the RBC and hemoglobin. In addition, the potential ability of HME to be used at a lower level (HME75) was observed.
Abstract
This study was conducted to investigate the effects of hot melt extrusion (HME) nano-iron as an alternative for the common ferrous sulfate on iron (Fe) bioavailability, growth performance, nutrient digestibility, intestinal morphology, and intestinal microbiota of weanling pigs. A total of 200 piglets (Landrace × Yorkshire × Duroc) were randomly allotted to seven treatments on the basis of initial body weight (BW) and sex. Treatments were the INO100 (100 ppm Fe as FeSO4), HME-Fe levels (50, 75, and 100 ppm nano-Fe as FeSO4). ORG100 (100 ppm Fe as iron methionine). In phase 1, the HME50 pigs showed the lowest Fe content in feed and feces. Plasma Fe concentration was increased in HME100 and ORG100 pigs. In phase 2, there were significantly lower concentration of Fe in feed and feces of HME50 pigs (p < 0.01). A lower Fe concentration in the plasma and liver were observed in HME50 pigs compared with HME100 pigs. Concentration of red blood cell (RBC) was the lowest (p < 0.01) for HME50 pigs. During phase 2, the HME100, HME75, and ORG100 pigs showed a higher RBC and hemoglobin values compared with HME50 pigs. Digestibility of gross energy (GE) and crude protein (CP) were significantly higher in HME100 pigs compared with HME50 pigs. There was an increased (p < 0.01) villus height in the duodenum and jejunum of HME100 pigs compared with HME50 pigs. It is concluded that dietary Fe does not improve growth performance of weanling pigs; however, increasing the dietary iron concentration in weanling piglets increased the RBC and hemoglobin. In addition, the potential ability of HME to be used at a lower level (HME75) was observed.
참고문헌 (27)
- Hansen SL, "Iron transporters are differentially regulated by dietary iron, and modifications are associated with changes in manganese metabolism in young pigs", J Nutr, 139, pp.1474~1479 (2009)
- Perri AM, "An investigation of iron deficiency and anemia in piglets and the effect of iron status at weaning on post-weaning performance", J Swine Health Prod, 24, pp.10~20 (2016)
- Feng J, "The effect of iron glycine chelate on tissue mineral levels, fecal mineral concentration, and liver antioxidant enzyme activity in weanling pigs", Anim Feed Sci Tech, 150, pp.106~113 (2009)
- Rincker MJ, "Effects of dietary iron supplementation on growth performance, hematological status, and whole-body mineral concentrations of nursery pigs", J Anim Sci, 82, pp.3189~3197 (2004)
- Yu B, "Bioavailability of iron from amino acid complex in weanling pigs", Anim Feed Sci Tech, 86, pp.39~52 (2000)
- Shinde PL, "Efficiency of inorganic and organic iron sources under iron depleted conditions in broilers", Br Poult Sci, 52, pp.578~583 (2011)
- Bunglavan SJ, "Use of nanoparticles as feed additives to improve digestion and absorption in livestock", Livestock Res Int, 2, pp.36~47 (2014)
- Desai MA, "A study of macromolecular diffusion through native porcine mucus", Experientia, 1, pp.22~26 (1992)
- Qiu K, "Inorganic nanoparticles and the microbiome", Nano Res, 11, pp.4936~4954 (2018)
- Lee SY, "Fabrication and characterizations of hot-melt extruded nanocomposites based on zinc sulfate monohydrate and soluplus", Appl Sci, 7, pp.902~ (2017)
- National Research Council, "Nutrient requirements of swine" (2012), National Academies Press
- AOAC, "Official methods of analysis" (1998), Association of Official Analytical Chemists
- Kececi T, "Effects of polyvinylpolypyrrolidone, synthetic zeolite and bentonite on serum biochemical and haematological characters of broiler chickens during aflatoxicosis", Br Poult Sci, 39, pp.452~458 (1998)
- Hosseindoust A, "A dose–response study to evaluate the effects of pH-stable β-mannanase derived from Trichoderma citrinoviride on growth performance, nutrient retention, and intestine morphology in broiler chickens", Ital J Anim Sci, pp.1~8 (2018)
- Lee SH, "Effects of dietary iron levels on growth performance, hematological status, liver mineral concentration, fecal microflora, and diarrhea incidence in weanling pigs", Biol Trace Elem Res, 126(Suppl 1), pp.57~68 (2008)
- National Research Council, "Nutrient requirements of swine" (1998), National Academies Press
- Feng J, "Effects of iron glycine chelate on growth, haematological and immunological characteristics in weanling pigs", Anim Feed Sci Tech, 134, pp.261~272 (2007)
- Lewis A, "Bioavailability of iron in two different sources for weanling pigs", Neb Swine Rep, 187, pp.22~24 (1996)
- Hosseindoust AR, "Dietary bacteriophages as an alternative for zinc oxide or organic acids to control diarrhoea and improve the performance of weanling piglets", Vet Med, 62, pp.53~61 (2017)
- Zhuo Z, "Heme and non-heme iron on growth performances, blood parameters, tissue mineral concentration, and intestinal morphology of weanling pigs", Biol Trace Elem Res, 187, pp.411~417 (2019)
- Kim JS, "Bacteriophage cocktail and multi-strain probiotics in the feed for weanling pigs : effects on intestine morphology and targeted intestinal coliforms and Clostridium", Animal, 11, pp.45~53 (2017)
- Kachuee R, "Effects of sodium selenite, L-selenomethionine, and selenium nanoparticles during late pregnancy on selenium, zinc, copper, and iron concentrations in Khalkhali Goats and their kids", Biol Trace Elem Res, pp.1~14 (2019)
- Underwood EJ, "The mineral nutrition of livestock" (1999), CABI Publishing
- 강옥득, "Effect of age on heart rate, blood lactate concentration, packed cell volume and hemoglobin to exercise in Jeju crossbreed horses", 한국축산학회지, 59(1), pp.1~6 (2017), 한국축산학회
- Zimmerman DR, "National Feed Ingredient Association literature review on iron in animal and poultry nutrition" (1980), National Feed Ingredients Association
- Miller ER, "Swine hematology from birth to maturity. II. Erythrocyte population, size and hemoglobin concentration", J Anim Sci, 20, pp.890~897 (1961)
- Dove CR, "The effect of copper addition to diets with various iron levels on the performance and hematology of weanling swine", J Anim Sci, 69, pp.2013~2019 (1991)