Hot-melt extruded copper sulfate affects the growth performance, meat quality, and copper bioavailability of broiler chickens
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Objective: This study was conducted to evaluate the effects of the supplementation of diets of broiler chickens with hot-melt extruded CuSO4 (HME-Cu) on their growth performance, nutrient digestibility, gut microbiota, small intestinal morphology, meat quality, and copper (Cu) bioavailability. Methods: A total of 225 broilers (Ross 308), one-day old and initial weight 39.14 g, were weighed and distributed between 15 cages (15 birds per cage) in a completely randomized experimental design with 3 treatments (diets) and 5 replicates per treatment. Cages were allotted to three treatments including control (without supplemental Cu), IN-Cu (16 mg/kg of CuSO4), and HME-Cu (16 mg/kg of HME processed CuSO4). Results: The HME-Cu treatment tended to increase the overall body weight gain (p<0.10). The apparent digestibility of Cu was increased by supplementation of HME-Cu at phase 2 (p<0.05). The Escherichia coli count in cecum tended to decrease with the supplementation with Cu (p<0.10). In addition, the HME-Cu treatment had a higher pH of breast meat than the control and IN-Cu treatments (p<0.05). Significant increases in the cooking loss, water-holding capacity, and lightness in the breast were observed in the HME-Cu treatment compared to the control (p<0.05). The Cu content of excreta increased with the Cu supplementation (p<0.05). The concentration of excreta Cu in broilers was decreased in the HME-Cu compared to the IN-Cu in phase 2 (p<0.05). The Cu concentration in the liver was increased with the HME-Cu supplementation, compared with the control diets (p<0.05). Conclusion: This study showed that HME-Cu supplementation at the requirement level (16 mg/kg diets) in broiler diets did not affect the growth performance and the physiological function of Cu in broilers. However, supplementation of Cu in HME form improved the meat quality and the bioavailability of Cu.
Abstract
Objective: This study was conducted to evaluate the effects of the supplementation of diets of broiler chickens with hot-melt extruded CuSO4 (HME-Cu) on their growth performance, nutrient digestibility, gut microbiota, small intestinal morphology, meat quality, and copper (Cu) bioavailability. Methods: A total of 225 broilers (Ross 308), one-day old and initial weight 39.14 g, were weighed and distributed between 15 cages (15 birds per cage) in a completely randomized experimental design with 3 treatments (diets) and 5 replicates per treatment. Cages were allotted to three treatments including control (without supplemental Cu), IN-Cu (16 mg/kg of CuSO4), and HME-Cu (16 mg/kg of HME processed CuSO4). Results: The HME-Cu treatment tended to increase the overall body weight gain (p<0.10). The apparent digestibility of Cu was increased by supplementation of HME-Cu at phase 2 (p<0.05). The Escherichia coli count in cecum tended to decrease with the supplementation with Cu (p<0.10). In addition, the HME-Cu treatment had a higher pH of breast meat than the control and IN-Cu treatments (p<0.05). Significant increases in the cooking loss, water-holding capacity, and lightness in the breast were observed in the HME-Cu treatment compared to the control (p<0.05). The Cu content of excreta increased with the Cu supplementation (p<0.05). The concentration of excreta Cu in broilers was decreased in the HME-Cu compared to the IN-Cu in phase 2 (p<0.05). The Cu concentration in the liver was increased with the HME-Cu supplementation, compared with the control diets (p<0.05). Conclusion: This study showed that HME-Cu supplementation at the requirement level (16 mg/kg diets) in broiler diets did not affect the growth performance and the physiological function of Cu in broilers. However, supplementation of Cu in HME form improved the meat quality and the bioavailability of Cu.
참고문헌 (52)
- Liao J, "Effects of copper on oxidative stress and autophagy in hypothalamus of broilers", Ecotoxicol Environ Saf, 185, pp.109710~ (2019)[DOI]
- Sharif M, "Copper nanoparticles as growth promoter, antioxidant and anti-bacterial agents in poultry nutrition : prospects and future implications", Biol Trace Elem Res, 199, pp.3825~3836 (2021)[DOI]
- Santos TS, "High levels of copper and zinc supplementation in broiler diets on growth performance, carcase traits and apparent ileal mineral absorption", Br Poult Sci, 62, pp.579~588 (2021)[DOI]
- Otowski K, "Growth rate, metabolic parameters and carcass quality in turkeys fed diets with different inclusion levels and sources of supplemental copper", J Anim Feed Sci, 28, pp.272~281 (2019)[DOI]
- Committee on Nutrient Requirements of Poultry, "Nutrient requirements of poultry" (1994), National Academy Press
- Aviagen, "Ross 308 Broiler : Nutrition Specifications" (2014), Aviagen Ltd
- Scott A, "Effect of different levels of copper nanoparticles and copper sulphate on performance, metabolism and blood biochemical profiles in broiler chicken", J Anim Physiol Anim Nutr, 102, pp.e364~e373 (2018)[DOI]
- Wu QJ, "Glutamine alleviates heat stress-induced impairment of intestinal morphology, intestinal inflammatory response, and barrier integrity in broilers", Poult Sci, 97, pp.2675~2683 (2018)[DOI]
- El-Kazaz SE, "Evaluation of copper nanoparticles and copper sulfate effect on immune status, behavior, and productive performance of broilers", J Adv Vet Anim Res, 7, pp.16~25 (2020)[DOI]
- Wu X, "Effects of copper sources and levels on lipid profiles, immune parameters, antioxidant defenses, and trace element residues in broilers", Biol Trace Elem Res, 194, pp.251~258 (2020)[DOI]
- Cano AP, "Copper sulfate-embedded and copper oxide-embedded filter paper and their antimicrobial properties", Mater Chem Phys, 207, pp.147~153 (2018)[DOI]
- Nguyen HTT, "Copper hydroxychloride is more efficacious than copper sulfate in improving broiler chicken's growth performance, both at nutritional and growth-promoting levels", Poult Sci, 99, pp.6964~6973 (2020)[DOI]
- Ghasemi HA, "Effect of advanced chelate technology based trace minerals on growth performance, mineral digestibility, tibia characteristics, and antioxidant status in broiler chickens", Nutr Metab, 17, pp.94~ (2020)[DOI]
- Gangadoo S, "Nanoparticles in feed : Progress and prospects in poultry research", Trends Food Sci Technol, 58, pp.115~126 (2016)[DOI]
- Ognik K, "The effect of administration of copper nanoparticles to chickens in their drinking water on the immune and antioxidant status of the blood", Anim Sci J, 89, pp.579~588 (2018)[DOI]
- Ognik K, "The effect of administration of copper nanoparticles in drinking water on redox reactions in the liver and breast muscle of broiler chickens", Ann Anim Sci, 19, pp.663~677 (2019)[DOI]
- El-Kassas S, "Dietary supplementation with copper oxide nanoparticles ameliorates chronic heat stress in broiler chickens", Anim Prod Sci, 60, pp.254~268 (2019)[DOI]
- Zhu Y, "A comparison of the effects of copper nanoparticles and copper sulfate on Phaeodactylum tricornutum physiology and transcription", Environ Toxicol Pharmacol, 56, pp.43~49 (2017)[DOI]
- Tiwari RV, "Contribution of hot-melt extrusion technology to advance drug delivery in the 21st century", Expert Opin Drug Deliv, 13, pp.451~464 (2016)[DOI]
- Vo AQ, "A novel floating controlled release drug delivery system prepared by hot-melt extrusion", Eur J Pharm Biopharm, 98, pp.108~121 (2016)[DOI]
- Lee SY, "Fabrication and characterizations of hot-melt extruded nanocomposites based on zinc sulfate monohydrate and soluplus", Appl Sci, 7, pp.902~ (2017)[DOI]
- Koo JS, "Preparation of cupric sulfatebased self-emulsifiable nanocomposites and their application to the photothermal therapy of colon adenocarcinoma", Biochem Biophys Res Commun, 503, pp.2471~2477 (2018)[DOI]
- 김민주, "사료 내 Hot Melt Extrusion 가공된 황산아연의 첨가가 이유자돈의 사양성적, 영양소 소화율, 소장의 형태학적 변화 및 분중 아연 배출에 미치는 영향", 동물자원연구, 28(4), pp.169~179 (2017), 동물생명과학연구소[DOI]
- 이준형, "Effects of hot melt extrusion processed nano-iron on growth performance, blood composition, and iron bioavailability in weanling pigs", 한국축산학회지, 61(4), pp.216~224 (2019), 한국축산학회[DOI]
- Lee JH, "Biological evaluation of hot-melt extruded nano-selenium and the role of selenium on the expression profiles of selenium-dependent antioxidant enzymes in chickens", Biol Trace Elem Res, 194, pp.536~544 (2020)[DOI]
- Lee JH, "Supplemental hot melt extruded nano-selenium increases expression profiles of antioxidant enzymes in the livers and spleens of weanling pigs", Anim Feed Sci Technol, 262, pp.114381~ (2020)[DOI]
- Kumar A, "Nano-sized zinc in broiler chickens : effects on growth performance, zinc concentration in organs, and intestinal morphology", J Poult Sci, 58, pp.21~29 (2021)[DOI]
- 오승민, "Hot melt extruded-based nano zinc as an alternative to the pharmacological dose of ZnO in weanling piglets", Animal Bioscience, 33(6), pp.992~1001 (2020), 아세아·태평양축산학회[DOI]
- Tang HC, "Mitsuokella jalaludinii supplementation improved nutrient utilization of broilers fed low-available phosphorus diet", Braz J Poult Sci, 23, pp.1~8 (2021)[DOI]
- Sifa D, "Dietary glutamine improves meat quality, skeletal muscle antioxidant capacity and glutamine metabolism in broilers under acute heat stress", J Appl Anim Res, 46, pp.1412~1417 (2018)[DOI]
- AOAC, "Official methods of analysis" (2007), Association of Official Analytical Chemists International
- Fenton TW, "An improved procedure for the determination of chromic oxide in feed and feces", Can J Anim Sci, 59, pp.631~634 (1979)[DOI]
- Kim MJ, "Effects of hot-melt extruded nano-copper as an alternative for the pharmacological dose of copper sulfate in weanling pigs", Biol Trace Elem Res, 199, pp.2929~2935 (2021)[DOI]
- Yoo JH, "Growth performance, intestinal morphology, and meat quality in relation to alpha-lipoic acid associated with vitamin C and E in broiler chickens under tropical conditions", Rev Bras Zootec, 45, pp.113~120 (2016)[DOI]
- Lee TT, "Effect of Pleurotus eryngii stalk residue on the oxidative status and meat quality of broiler chickens", J Agric Food Chem, 60, pp.11157~11163 (2012)[DOI]
- STAT User’s guide : version 9, "SAS", pp.2002, SAS Institute Inc
- Scott A, "Copper nanoparticles as an alternative feed additive in poultry diet : a review", Nanotechnol Rev, 7, pp.69~93 (2018)[DOI]
- Forouzandeh A, "Effects of dicopper oxide and copper sulfate on growth performance and gut microbiota in broilers", Poult Sci, 100, pp.101224~ (2021)[DOI]
- Wang C, "Effects of copperloaded chitosan nanoparticles on growth and immunity in broilers", Poult Sci, 90, pp.2223~2228 (2011)[DOI]
- JunHyung Lee, "Effects of hot-melt extruded nanocopper on the Cu bioavailability and growth of broiler chickens", 한국축산학회지, 63(2), pp.295~304 (2021), 한국축산학회[DOI]
- Gonzales-Eguia A, "Effects of nanocopper on copper availability and nutrients digestibility, growth performance and serum traits of piglets", Livest Sci, 126, pp.122~129 (2009)[DOI]
- Linder MC, "Copper homeostasis in mammals, with emphasis on secretion and excretion. a review", Int J Mol Sci, 21, pp.4932~ (2020)[DOI]
- "J Anhui Agric Sci", 2007, 6122~
- Vincent M, "Contact killing and antimicrobial properties of copper", J Appl Microbiol, 124, pp.1032~1046 (2018)[DOI]
- Pang Y, "The influence of copper concentration and source on ileal microbiota", Poult Sci, 88, pp.586~592 (2009)[DOI]
- Xia MS, "Effects of copper-bearing montmorillonite on growth performance, digestive enzyme activities, and intestinal microflora and morphology of male broilers", Poult Sci, 83, pp.1868~1875 (2004)[DOI]
- Attia YA, "Effect of inorganic or organic copper additions on reproductive performance, lipid metabolism and morphology of organs of dual-purpose breeding hens", Arch Geflügelk, 75, pp.169~178 (2011)
- Canoğulları S, "Differences in performance, carcass characteristics and meat quality between fast-and slow-growing broiler genotypes", Prog Nutr, 21, pp.558~565 (2019)[DOI]
- Beauclercq S, "Serum and muscle metabolomics for the prediction of ultimate pH, a key factor for chicken-meat quality", J Proteome Res, 15, pp.1168~1178 (2016)[DOI]
- Winiarska-Mieczan A, "The effects of copperglycine complexes on chemical composition and sensory attributes of raw, cooked and grilled chicken meat", J Food Sci Technol, 52, pp.4226~4235 (2015)[DOI]
- Mroczek-Sosnowska N, "In ovo administration of copper nanoparticles and copper sulfate positively influences chicken performance", J Sci Food Agric, 96, pp.3058~3062 (2016)[DOI]
- Wen A, "Copper bioavailability, mineral utilization, and lipid metabolism in broilers", Czech J Anim Sci, 64, pp.483~490 (2019)[DOI]