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In vitro screening of elastase, collagenase, hyaluronidase, and tyrosinase inhibitory and antioxidant activities of 22 halophyte plant extracts for novel cosmeceuticals

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주제분류수산학

초록

Background: Halophyte plant (HPs), a salt-resistant flora, has been reported to provide several health benefits, but the knowledge of its cosmeceutical potential is still ambiguous. Here, 70% ethanol extracts of 22 HPs collected from along the coast of South Korea were investigated for their potentials of antioxidant, anti-aging, and whitening properties for use as materials in novel cosmeceuticals. Methods: Antioxidant activities were determined by DPPH (1,1-diphenyl-2-pricrylhydrazyl) free radical and hydrogen peroxide scavenging assays, and skin aging-related enzyme activities (anti-elastase, anti-collagenase, antihyaluronidase, and anti-tyrosinase) were evaluated by using the spectrophotometric method. Results: Among the 22 HPs, we found that Ischaemum antephoroides f. coreana and Atriplex gmelinii extracts presented the strongest scavenging effects against DPPH free radical and hydrogen peroxide, respectively. Our finding additionally suggested that Salicornia europaea extract might provide a major source of anti-elastase and anti-hyaluronidase; meanwhile, Rosa rugosa extract showed the highest anti-collagenase effect. Furthermore, the highest tyrosinase inhibitory activity was possessed by Spartina anglica extract. Conclusion: These findings may suggest that halophyte plants showing biological activities may be potent inhibitors of tyrosinase, elastase, collagenase, and hyaluronidase and could be useful for application in cosmeceuticals.

Abstract

Background: Halophyte plant (HPs), a salt-resistant flora, has been reported to provide several health benefits, but the knowledge of its cosmeceutical potential is still ambiguous. Here, 70% ethanol extracts of 22 HPs collected from along the coast of South Korea were investigated for their potentials of antioxidant, anti-aging, and whitening properties for use as materials in novel cosmeceuticals. Methods: Antioxidant activities were determined by DPPH (1,1-diphenyl-2-pricrylhydrazyl) free radical and hydrogen peroxide scavenging assays, and skin aging-related enzyme activities (anti-elastase, anti-collagenase, antihyaluronidase, and anti-tyrosinase) were evaluated by using the spectrophotometric method. Results: Among the 22 HPs, we found that Ischaemum antephoroides f. coreana and Atriplex gmelinii extracts presented the strongest scavenging effects against DPPH free radical and hydrogen peroxide, respectively. Our finding additionally suggested that Salicornia europaea extract might provide a major source of anti-elastase and anti-hyaluronidase; meanwhile, Rosa rugosa extract showed the highest anti-collagenase effect. Furthermore, the highest tyrosinase inhibitory activity was possessed by Spartina anglica extract. Conclusion: These findings may suggest that halophyte plants showing biological activities may be potent inhibitors of tyrosinase, elastase, collagenase, and hyaluronidase and could be useful for application in cosmeceuticals.

참고문헌 (52)

  1. Aghaleh M, "Effect of salt stress on physiological and antioxidative responses in two species of Salicornia (S. persica and S. europaea)", Acta Physiol Plant, 33, pp.1261~1270 (2010)
  2. K. K. Asanka Sanjeewa, "Soft corals collected from Jeju Island inhibits the α-MSH-induced melanogenesis in B16F10 cells through activation of ERK", Fisheries and Aquatic Sciences, 21(3), pp.1~8 (2018), 한국수산과학회
  3. Bauman L, "CosmoDerm", CosmoPlast(human bioengineered collagen)for the aging face, 2004, pp.20, 125~128
  4. Carvalho IS, "Phenolic composition and antioxidant capacity of six artemisia species", Ind Crops Prod, 33(2), pp.382~388 (2011)
  5. Chanda SV, "Antioxidant and metal chelating activities of Lagenaria siceraria(Molina)Standl peel, pulp and aerial parts in relation to their total phenol and flavonoid content", Phcog J, 7(1), pp.64~73 (2015)
  6. Chatatikun M, "Thai plants with high antioxidant levels, free radical scavenging activity, anti-tyrosinase and anti-collagenase activity", BMC Complement Altern Med, 17, pp.487~ (2017)
  7. Chatatikun M, "Anti melanogenic effect of Croton roxburghii and Croton sublyratus leaves in α-MSH stimulated B16F10 cells", J of Tradit Complement Med, 9(1), pp.66~72 (2019)
  8. 최은경, "Extraction conditions of white rose petals for the inhibition of enzymes related to skin aging", Laboratory Animal Research, 31(3), pp.148~152 (2015), 한국실험동물학회
  9. Ding YL, "Hyaluronidase inhibitory and antioxidant activities of enzymatic hydrolysate from Jeju Island red sea cucumber(Stichopus japonicus)for novel anti-aging cosmeceuticals", J Marine Bioscience Biotechnology, 10(2), pp.62~72 (2018)
  10. Dudonné S, "Phenolic composition and antioxidant properties of poplar bud(Populus nigra)extract : individual antioxidant contribution of phenolics and transcriptional effect on skin aging", J Agric Food Chem, 59(9), pp.4527~4536 (2011)
  11. Fulop T, "The role of elastin peptides in modulating the immune response in aging and age-related diseases", Pathol Biol, 60(1), pp.28~33 (2012)
  12. Heo SJ, "Antioxidant activities of enzymatic extracts from brown seaweeds", Bioresour Technol, 96(14), pp.1613~1623 (2005)
  13. Horng CT, "Inhibitory effect of burdock leaves on elastase and tyrosinase activity", Exp Ther Med, 14(4), pp.3247~3252 (2017)
  14. Jdey A, "Antiaging activities of extracts from Tunisian medicinal halophytes and their aromatic constituents", EXCLI J, 16, pp.755~769 (2017)
  15. Jegasothy SM, "Efficacy of a new topical nanohyaluronic acid in humans", J Clin Aesthet Dermatol, 7(3), pp.27~29 (2014)
  16. Kang M, "Anti-melanogenic effects of resorcinol are mediated by suppression of cAMP signaling and activation of p38 MAPK signaling", Biosci Biotechnol Biochem, 82(7), pp.1188~1196 (2018)
  17. Kendall AC, "Bioactive lipid mediators in skin inflammation and immunity", Prog Lipid Res, 52(1), pp.141~164 (2013)
  18. 김지우, "해당화(Rosa rugosa Thunb.) 부위별 열수추출물의 항산화 활성 분석", 목재공학, 46(1), pp.38~47 (2018), 한국목재공학회
  19. Kim M, "In vitro screening of subtropical plants cultivated in Jeju Island for cosmetic ingredients", Orient J Chem, 32, pp.807~815 (2016)
  20. 김미자, "Radical Scavenging Activity and Anti-obesity Effects in 3T3-L1 Preadipocyte Differentiation of Ssuk (Artemisia princeps Pamp.) Extract", Food Science and Biotechnology, 19(2), pp.535~540 (2010), 한국식품과학회
  21. Ko EY, "Evaluation on antioxidant properties of sixteen plant species from Jeju Island in Korea", EXCLI J, 14, pp.133~145 (2015)
  22. Küpeli E, "Comparative evaluation of the antiinflammatory and antinociceptive activity of Turkish Eryngium species", J Ethnopharmacol, 107(1), pp.32~37 (2006)
  23. Leach JB, "Photocrosslinked hyaluronic acid hydrogels : natural, biodegradable tissue engineering scaffolds", Biotechnol Bioeng, 82(5), pp.578~589 (2003)
  24. Hee Ju Lee, "Online High Performance Liquid Chromatography (HPLC)-ABTS+ Based Assay and HPLC-Electrospray Ionization Mass Spectrometry Analysis of Antioxidant Phenolic Compounds in Salsola komarovii", Applied Biological Chemistry, 55(2), pp.317~321 (2012), 한국응용생명화학회[DOI]
  25. Lee JH, "Isoflavone characterization and antioxidant activity of Ohio soybeans", J Agric Food Chem, 52(9), pp.2647~2651 (2004)
  26. 이정민, "Antioxidant and Anti-inflammatory Activity of Six Halophytes in Korea", Natural Product Sciences, 24(1), pp.40~46 (2018), 한국생약학회
  27. 이정민, "Comparison of Biological Activities of Korean Halophytes", Natural Product Sciences, 24(4), pp.247~252 (2018), 한국생약학회
  28. Liyanaarachchi GD, "Tyrosinase, elastase, hyaluronidase, inhibitory and antioxidant activity of Sri Lankan medicinal plants for novel cosmeceuticals", Ind Crops Prod, 111, pp.597~605 (2018)
  29. Meot-Duros L, "Radical scavenging, antioxidant and antimicrobial activities of halophytic species", J Ethnopharmacol, 116(2), pp.258~262 (2008)
  30. Moon JY, "Screening of elastase and tyrosinase inhibitory activity from Jeju Island plants", EurAsia J BioSci, 4, pp.41~53 (2010)
  31. Müller HE, "Detection of hydrogen peroxide produced by microorganisms on an ABTS peroxidase medium", Zentralbl Bakteriol Mikrobiol Hyg A, 259(2), pp.151~154 (1985)
  32. Nanjo F, "Scavenging effects of tea catechins and their derivatives on 1, 1-diphenyl-2-picrylhydrazyl radical", Free Radic Biol Med, 21(6), pp.895~902 (1996)
  33. Ndlovu G, "In vitro determination of the anti-aging potential of four southern African medicinal plants", BMC Complement Altern Med, 13, pp.304~ (2013)
  34. Ng TB, "A gallic acid derivative and polysaccharides with antioxidative activity from rose(Rosa rugosa)flowers", J Pharm Pharmacol, 56(4), pp.20~ (2004)
  35. No JK, "Inhibition of tyrosinase by green tea components", Life Sci, 65(21), pp.PL241~PL246 (1999)
  36. Olech M, "Hyaluronidase, acetylcholinesterase inhibiting potential, antioxidant activity, and LC-ESI-MS", MS analysis of polyphenolics of rose (Rosa rugosa Thunb.) teas and tinctures, 2017, pp.20(S1), S16~S25
  37. Paliwal S, "Skin extracellular matrix stimulation following injection of a hyaluronic acid-based dermal filler in a rat model", Plast Reconstr Surg, 134(6), pp.1224~1233 (2014)
  38. Palmer DM, "Oxidative damage, skin aging, antioxidants and a novel antioxidant rating system", J Drugs Dermatol, 9(1), pp.11~15 (2010)
  39. Peres PS, "Photoaging and chronological aging profile : understanding oxidation of the skin", J Photochem Photobiol B, 103(2), pp.93~97 (2011)
  40. Popoola OK, "Inhibition of oxidative stress and skin aging-related enzymes by prenylated chalcones and other flavonoids from Helichrysum teretifolium", Molecules, 20(4), pp.7143~7155 (2015)
  41. Qin P, "Spartina green food ecological engineering", Ecol Eng, 11, pp.147~156 (1998)
  42. Sahasrabudhe A, "Anti-hyaluronidase, anti-elastase activity of Garcinia indica", Int J Botany, 6, pp.299~303 (2010)
  43. Siedle B, "Sesquiterpene lactones as inhibitors of human neutrophil elastase", Bioorg Med Chem, 10(9), pp.2855~2861 (2002)
  44. Thring TS, "Anti-collagenase, anti-elastase and antioxidant activities of extracts from 21 plants", BMC Complement Altern Med, 9, pp.27~ (2009)
  45. Tu PTB, "Anti-oxidant, anti-aging, and anti-melanogenic properties of the essential oils from two varieties of Alpinia zerumbet", Molecules, 20, pp.16723~16740 (2015)
  46. Varani J, "Molecular mechanisms of intrinsic skin aging and retinoid-induced repair and reversal", J Investig Dermatol Symp Proc, 3(1), pp.57~60 (1998)
  47. Wang L, "Protective effect of sulfated polysaccharides from Celluclast-assisted extract of Hizikia fusiforme against ultraviolet B-induced skin damage by regulating NF-κB, AP-1, and MAPKs signaling pathways in vitro in human dermal fibroblasts", Mar Drugs, 16(7), pp.239~ (2018)
  48. Wittenauer J, "Inhibitory effects of polyphenols from grape pomace extract on collagenase and elastase activity", Fitoterapia, 101, pp.179~187 (2015)
  49. Won KJ, "Desalted Salicornia europaea extract attenuated vascular neointima formation by inhibiting the MAPK pathway-mediated migration and proliferation in vascular smooth muscle cells", Biomed Pharmacother, 94, pp.430~438 (2017)
  50. Yang EJ, "In vitro screening of Korean halophytes for cosmeceutical ingredients", Int J Chemtech Res, 9(8), pp.541~547 (2016)
  51. Youwei Z, "Changes in antioxidant activity in Rosa rugosa flowers at different stages of development", N Z J Crop Hortic Sci, 35(4), pp.397~401 (2007)
  52. Zheng J, "Total phenolics and antioxidants profiles of commonly consumed edible flowers in China", Int J Food Prop, 21(1), pp.1524~1540 (2018)

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